Sorption conditioning of eluate of 68Ge/68Ga generator for medical purposes

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• 作者：V. G. Andronov ; A. B. Bruskin ; A. S. Sevast’yanova ; G. E. Kodina ; A. V. Ochkin and G. V. Myasoedova
• 关键词：PACS numbers 87.58Ji
• 刊名：Radiochemistry
• 出版年：2008
• 出版时间：October, 2008
• 年：2008
• 卷：50
• 期：5
• 页码：535-540
• 全文大小：243.7 KB
• 刊物类别：Chemistry and Materials Science
• 刊物主题：Chemistry
  Nuclear Chemistry
  Chemistry
  Russian Library of Science
  
• 出版者：MAIK Nauka/Interperiodica distributed exclusively by Springer Science+Business Media LLC.
• ISSN：1608-3288

文摘

The possibility of using fibrous filled sorbents for efficient purification and conditioning of the eluate of a 68Ge/68Ga generator was demonstrated. The eluate thus prepared was used to label octreo-tide with 68Ga with the aim to obtain a radiopharmaceutical for imaging neuroendocrine and other tumors by positron emission tomography. A pilot installation for prompt and reliable conditioning of the eluate of a 68Ge/68Ga generator was designed and fabricated. The resulting eluate was used to label the modified peptide on the nanomolar level in a high yield.