Lupus erythematodes
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  • 作者:Ao Univ.-Prof. Dr. E. Aberer (1)
  • 关键词:Lupus erythematodes ; Unspezifische Symptome ; Antiphospholipidsyndrom ; Urtikariavaskulitis ; Komplementmangel ; Koexistenzen ; LE ; Imitatoren ; Lupus erythematosus ; Nonspecific symptoms ; Antiphospholipid syndrome ; Urticaria vasculitis ; Complement deficiency ; Coexistences ; LE imitators
  • 刊名:Der Hautarzt
  • 出版年:2010
  • 出版时间:August 2010
  • 年:2010
  • 卷:61
  • 期:8
  • 页码:676-682
  • 全文大小:460KB
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  • 作者单位:Ao Univ.-Prof. Dr. E. Aberer (1)

    1. Univ.-Klinik für Dermatologie, Medizinische Universit?t Graz, Auenbrugger Platz 8, 8036, Graz, ?sterreich
  • ISSN:1432-1173
文摘
The typical clinical forms of cutaneous lupus erythematosus (LE) are the butterfly rash, acute, subacute and chronic cutaneous lupus, intermediate lupus (lupus tumidus), chilblain- and bullous lupus, lupus profundus, and ulcerating lesions on the mucous membrane. Besides the typical lupus forms, nonspecific skin lesions are also observed such as dermal mucinosis, acneiform skin lesions, different variants of livedo, necrotizing vasculitis with ulcers, purpura, urticaria vasculitis, neutrophilic dermatosis, hyperpigmentation, hair and nail changes as well as overlap syndromes with erythema multiforme, scleroderma, Sj?gren syndrome, Raynaud phenomenon, lichen planus, bullous pemphigoid und psoriasis. There are lupus imitators which create differential diagnostic challenges, such as infections with atypical mycobacteria or subcutaneous T-cell lymphoma both of which are similar to lupus profundus. All these skin lesions can present as maximal pathological findings seen in lupus or be caused by a variety of pathological laboratory findings such as the anti-phospholipid antibodies or a deficiency of complement factors. In the latter situation severe lupus often with complications can be expected.

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