Inhibitory effects of serum from sepsis patients on epithelial cell migration in vitro: a case control study
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- 作者：Henna Jaurila ; Vesa Koivukangas ; Marjo Koskela…
- 关键词：Sepsis ; Human serum ; Migration ; EGF ; TNF ; α ; Exosome ; HaCaT ; In vitro
- 刊名：Journal of Translational Medicine
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：15
- 期：1
- 全文大小：1889KB
- 刊物主题：Biomedicine, general; Medicine/Public Health, general;
- 出版者：BioMed Central
- ISSN：1479-5876
- 卷排序：15
文摘
BackgroundSepsis delays wound re-epithelialization. In this study we explored the effect of human sepsis sera as well as the effects of cytokines, growth factors and exosomes of sepsis sera treated normal fibroblasts (NF) on keratinocyte migration and proliferation in vitro.