Local defects in the nanostructure of the membrane of erythrocytes upon ionizing radiation of blood

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• 作者：E. K. Kozlova ; V. A. Sergunova ; E. A. Krasavin…
• 刊名：Physics of Particles and Nuclei Letters
• 出版年：2016
• 出版时间：January 2016
• 年：2016
• 卷：13
• 期：1
• 页码：140-148
• 全文大小：2,503 KB
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• 作者单位：E. K. Kozlova (1) (2)
  V. A. Sergunova (1)
  E. A. Krasavin (3)
  A. V. Boreyko (3)
  A. V. Zavialova (1)
  A. P. Kozlov (2)
  A. M. Chernysh (1) (2)
  
  1. Negovsky Scientific Research Institute of General Reanimatology, Moscow, Russia
  2. Sechenov First Moscow State Medical University, Moscow, Russia
  3. Joint Institute for Nuclear Research, Dubna, Russia
  
• 刊物类别：Physics and Astronomy
• 刊物主题：Physics
  Elementary Particles and Nuclei
  Russian Library of Science
  
• 出版者：MAIK Nauka/Interperiodica distributed exclusively by Springer Science+Business Media LLC.
• ISSN：1531-8567

文摘

The purpose of the study is to investigate local topological defects in the erythrocyte membranes resulting from the ultraviolet (UV) radiation of blood in vitro. Biological effects in the erythrocytes after exposure to UV radiation at a wavelength of 254 nm are equivalent to those after γ radiation. It has been shown that oxidative processes developing in a suspension upon UV radiation result in the disruption of the nanostructure of the membranes of erythrocytes. In the experiments, typical topological defects in the membrane nanostructure were observed. The parameters of the defects differed from the characteristics of the nanostructure of the control cell membrane without irradiation. The characteristic dimensions of the topological defects are commensurate with the size of the spectrin matrix. As a result of the exposure to the UV radiation, polymorphism of the erythrocytes was observed. Original Russian Text © E.K. Kozlova, V.A. Sergunova, E.A. Krasavin, A.V. Boreyko, A.V. Zavialova, A.P. Kozlov, A.M. Chernysh, 2016, published in Pis’ma v Zhurnal Fizika Elementarnykh Chastits i Atomnogo Yadra, 2016.