Russell’s viper envenomation-associated acute kidney injury in children in Southern India

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• 作者：Sriram Krishnamurthy ; Kuralvanan Gunasekaran ; Subramanian Mahadevan…
• 关键词：Bleeding ; Complications ; Management ; Outcome ; Snakebite
• 刊名：Indian Pediatrics
• 出版年：2015
• 出版时间：July 2015
• 年：2015
• 卷：52
• 期：7
• 页码：583-586
• 全文大小：433 KB
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• 作者单位：Sriram Krishnamurthy (1)
  Kuralvanan Gunasekaran (1)
  Subramanian Mahadevan (1)
  Zachariah Bobby (2)
  Ajith Prabhu Kumar (3)
  
  1. From Departments of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India
  2. From Departments of Biochemistry, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India
  3. From Departments of Community Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India
  
• 刊物主题：Pediatrics; Pediatric Surgery; Maternal and Child Health;
• 出版者：Springer India
• ISSN：0974-7559

文摘

Objectives To determine the frequency and risk factors of acute kidney injury in children with Russell’s viper envenomation using Acute Kidney Injury Network definition and classification system. Methods A prospective observational study recruiting 61 subjects managed as per the National Snakebite Protocol. Results 45.9% of envenomed children had acute kidney injury. The median (IQR) of the maximum serum creatinine level during hospitalization was 2 (1.3-.8) mg/dL. The distribution of stages 1, 2 and 3 of acute kidney injury was 32.1%, 17.9% and 50% respectively. Dialysis was required in 35.7% of the children with acute kidney injury. Conclusions Acute kidney injury is common with Russell’s viper envenomation. Native treatments and bleeding manifestations were associated with acute kidney injury in our patient population.