Deep penetrating nevus: a case report and brief literature review

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• 作者：Victor S Flauta (1)
  Daniel C Lingamfelter (1)
  Linh M Dang (2)
  Kamani M Lankachandra (1)
  
• 刊名：Diagnostic Pathology
• 出版年：2006
• 出版时间：December 2006
• 年：2006
• 卷：1
• 期：1
• 全文大小：1095KB
• 参考文献：1. Hassan AS, Schulte KW, Ruzicka T, Megahed M: Linear arrangement of multiple deep penetrating nevi. / Arch Dematol 2003, 139:1608鈥?610. CrossRef
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  3. Barnhill RL, Milm MC, Margo CM: Plexiform spindle cell nevus: a distinctive variant of plexiform melanocytic naevus. / Histopathology 1991, 18:243鈥?47. CrossRef
  4. Mehragan DA, Mehragan AH: Deep penetrating nevus. / Arch Dermatol 1993, 129:328鈥?31. CrossRef
  5. Cooper PH: Deep penetrating (plexiform spindle cell) nevus. A frequent participant in combined nevus. / J Cutan Pathol 1992, 19:172鈥?80. CrossRef
  6. Robson A, Morley-Quante M, Hempel H, McKee PH, Calonje E: Deep penetrating naevus: clinicopathological study of 31 cases with further delineation of histological features allowing distinction from other pigmented benign melanocytic lesions and melanoma. / Histopathology 2003, 43:529鈥?37. CrossRef
  7. Ball NJ, Golitz LE: Melanocytic nevi with focal atypical epithelioid cell components: a review of seventy-three cases. / J Am Acad Dermatol 1994,30(5 Pt 1):724鈥?. CrossRef
  
• 作者单位：Victor S Flauta (1)
  Daniel C Lingamfelter (1)
  Linh M Dang (2)
  Kamani M Lankachandra (1)
  
  1. Department of Pathology, University of Missouri-Kansas City School of Medicine and Truman Medical Centers, Kansas City, Missouri, USA
  2. Department of Pathology, Baylor College of Medicine, Houston, Texas, USA
  

文摘

Background - Deep penetrating nevus (DPN) is a distinct variant of melanocytic nevus and remains a histopathologic challenge to pathologists because of its resemblance to blue nevus, malignant melanoma, pigmented Spitz nevus, and congenital melanocytic nevus. It often goes unrecognized due to its relative rarity. Case presentation - Here we report a case of DPN of the left anterior leg in a 51-year old female. A brief review of the literature shows that these lesions have a distinct growth pattern and cellular morphology that can differentiate these lesions from other entities including malignant melanoma. Conclusion - It is important to recognize these features because DPN carries a better prognosis than malignant melanoma.