Decreased Levels of Circulating Cancer-Associated Protein Biomarkers Following Bariatric Surgery

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• 作者：John Edward Farey ; Oliver M. Fisher ; Angelique J. Levert-Mignon…
• 关键词：Bariatric surgery ; Neoplasms ; Biological markers ; Gastrectomy ; Neoplasms/prevention and control ; Laparoscopy
• 刊名：Obesity Surgery
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：27
• 期：3
• 页码：578-585
• 全文大小：326KB
• 刊物主题：Surgery;
• 出版者：Springer US
• ISSN：1708-0428
• 卷排序：27

文摘

BackgroundEpidemiological studies have identified obesity as a major risk factor for cancer in humans, and trials have demonstrated a significant reduction in the incidence of cancer after bariatric surgery. The rapidity of weight loss after bariatric surgery provides an opportunity to identify the molecular changes associated with effective obesity treatment. Indirectly, this may provide some insights into the mechanisms that drive the association between obesity and cancer. We sought to measure circulating cancer-associated proteins before and after laparoscopic sleeve gastrectomy (LSG).