Adhesive Materials with Bioprotective/Biopromoting Functions
详细信息    查看全文
  • 作者:Sai Ma ; Lina Niu ; Fang Li ; Ming Fang ; Ling Zhang…
  • 关键词:Dental adhesives ; Bioprotective ; Biopromoting ; Antibacterial ; MMPs ; Collagen cross ; linking ; Remineralization ; Pulp regeneration
  • 刊名:Current Oral Health Reports
  • 出版年:2014
  • 出版时间:December 2014
  • 年:2014
  • 卷:1
  • 期:4
  • 页码:213-221
  • 全文大小:344KB
  • 参考文献:Papers of particular interest, published recently, have been highlighted as: 鈥?Of importance 鈥⑩€?Of major importance1.Bagramian RA, Garcia-Godoy F, Volpe AR. The global increase in dental caries. A pending public health crisis. Am J Dent. 2009;22:3鈥?.PubMed
    2.Sakaguchi RL. Review of the current status and challenges for dental posterior restorative composites: clinical, chemistry, and physical behavior considerations. Dent Mater. 2005;21:3鈥?.PubMed CrossRef
    3.Demarco FF, Correa MB, Cenci MS, Moraes RR, Opdam NJ. Longevity of posterior composite restorations: not only a matter of materials. Dent Mater. 2012;28:87鈥?01.PubMed CrossRef
    4.Ferracane JL. Resin composite: state of the art. Dent Mater. 2011;27:29鈥?8.PubMed CrossRef
    5.Imazato S. Antibacterial properties of resin compositesand dentin bonding systems. Dent Mater. 2003;19:449鈥?7.PubMed CrossRef
    6.Takahashi Y, Imazato S, Kaneshiro AV, Ebisu S, Frencken JE, Tay FR. Antibacterial effects and physical properties of glass-ionomer cements containing chlorhexidine for the ART approach. Dent Mater. 2006;22:647鈥?2.PubMed CrossRef
    7.Orug BO, Baysallar M, Cetiner D, Kucukkaraaslan A, Dogan B, Doganci L, et al. Increased antibacterial activity of zinc polycarboxylate cement by the addition of chlorhexidinegluconate in fixed prosthodontics. Int J Prosthodont. 2005;18:377鈥?2.PubMed
    8.鈥?/div>Stanislawczuk R, Reis A, Malaquias P, Pereira F, Farago PV, Meier MM, et al. Mechanical properties and modeling of drug release from chlorhexidine-containing etch-and-rinse adhesives. Dent Mater. 2014;30:392鈥?. This paper evaluated the effects of chlorhexidine addition into simplified聽etch-and-rinse adhesives聽on the ultimate tensile strength, water sorption, solubility, and the rate of chlorhexidine聽release聽over time. The authors demonstrate that the incorporation of chlorhexidine to commercial adhesive is a feasible method to provide a controlled聽release聽of CHX over time without jeopardizing the mechanical properties of the聽adhesives. PubMed CrossRef
    9.Stanislawczuk R, Pereira F, Mu帽oz MA, Luque I, Farago PV, Reis A, et al. Effects of chlorhexidine-containing adhesives on the durability of resin-dentine interfaces. J Dent. 2014;42:39鈥?7.PubMed CrossRef
    10.De Munck J, Van den Steen PE, Mine A, Van Landuyt KL, Poitevin A, Opdenakker G, et al. Inhibition of enzymatic degradation of adhesive-dentin interfaces. J Dent Res. 2009;88:1101鈥?.PubMed CrossRef
    11.Zhou J, Tan J, Yang X, Xu X, Li D, Chen L. MMP-inhibitory effect of chlorhexidine applied in a self-etching adhesive. J Adhes Dent. 2011;13:111鈥?.PubMed
    12.De Munck J, Mine A, Van den Steen PE, Van Landuyt KL, Poitevin A, Opdenakker G, et al. Enzymatic degradation of adhesive-dentin interfaces produced by mild self-etch adhesives. Eur J Oral Sci. 2010;118:494鈥?01.PubMed CrossRef
    13.Hiraishi N, Yiu CK, King NM, Tay FR. Effect of chlorhexidine incorporation into a self-etching primer on dentine bond strength of a luting cement. J Dent. 2010;38:496鈥?02.PubMed CrossRef
    14.Huang L, Xiao YH, Xing XD, Li F, Ma S, Qi LL, et al. Antibacterial activity and cytotoxicity of two novel cross-linking antibacterial monomers on oral pathogens. Arch Oral Biol. 2011;56:367鈥?3.PubMed CrossRef
    15.鈥?/div>Cheng YJ, Zeiger DN, Howarter JA, Zhang X, Lin NJ, Antonucci JM, et al. In situ formation of silver nanoparticles in photo crosslinking polymers. J Biomed Mater Res B. 2011;97:124鈥?1. This paper described the preparation of methacrylate polymers containing silver nanoparticles by coupling photo-initiated free radical polymerization of dimethacrylates with in situ silver ion reduction. They demonstrate that, with this technique, nanocomposites with substantial antibacterial effect and acceptable mechanical properties can be synthesized. CrossRef
    16.Cheng L, Zhang K, Melo MA, Weir MD, Zhou X, Xu HH. Anti-biofilm dentinprimer with quaternary ammonium and silver nanoparticles. J Dent Res. 2012;91:598鈥?04.PubMed CrossRef PubMed Central
    17.Zhang K, Melo MA, Cheng L, Weir MD, Bai Y, Xu HH. Effect of quaternaryammonium and silver nanoparticle-containing adhesives on dentin bond strength anddental plaque microcosm biofilms. Dent Mater. 2012;28:842鈥?2.PubMed CrossRef PubMed Central
    18.Cheng L, Zhang K, Weir MD, Liu H, Zhou X, Xu HH. Effects of antibacterial primers with quaternary ammonium and nano-silver on Streptococcus mutans impregnated in human dentin blocks. Dent Mater. 2013;29:462鈥?2.PubMed CrossRef PubMed Central
    19.Zhang K, Cheng L, Imazato S, Antonucci JM, Lin NJ, Lin-Gibson S, et al. Effects of dual antibacterial agents MDPB and nano-silver in primer on microcosm biofilm, cytotoxicity and dentine bond properties. J Dent. 2013;41:464鈥?4.PubMed CrossRef PubMed Central
    20.Li F, Weir MD, Fouad AF, Xu HH. Effect of聽salivary pellicle聽on antibacterial activity of novel antibacterial聽dental聽adhesives using adental聽plaque microcosm biofilm model. Dent Mater. 2014;30:182鈥?1.PubMed CrossRef PubMed Central
    21.Li F, Weir MD, Chen J, Xu HH. Comparison of quaternary ammonium-containing with nano-silver-containing adhesive in antibacterial properties and cytotoxicity. Dent Mater. 2013;29:450鈥?1.PubMed CrossRef PubMed Central
    22.Imazato S, Torii M, Tsuchitani Y, McCabe JF, Russell RRB. Incorporation of bacterial inhibitor into resin composite. J Dent Res. 1994;73:1437鈥?3.PubMed
    23.鈥⑩€?/div>Imazato S, Ma S, Chen JH, Xu HH. Therapeutic polymers for dental adhesives: loading resins with bio-active components. Dent Mater. 2014;30:97鈥?04. This review summarized the latest achievements in the development of therapeutic dental adhesives. Adhesives with antibacterial activities or remineralization effects were thoroughly discussed in this paper. PubMed CrossRef
    24.Ma S, Izutani N, Imazato S, Chen JH, Kiba W, Yoshikawa R, et al. Assessment of bactericidal effects of quaternary ammonium-based antibacterial monomers in combination with colloidal platinum nanoparticles. Dent Mater J. 2012;31:150鈥?.PubMed CrossRef
    25.Huang L, Sun X, Xiao YH, Dong Y, Tong ZC, Xing XD, et al. Antibacterial effect of a resin incorporating a novel polymerizable quaternary ammonium salt MAE-DB against Streptococcus mutans. J Biomed Mater Res B Appl Biomater. 2012;100:1353鈥?.PubMed CrossRef
    26.Antonucci JM, Zeiger DN, Tang K, Lin-Gibson S, Fowler BO, Lin NJ. Synthesis and characterization of dimethacrylates containing quaternary ammonium functionalities for dental applications. Dent Mater. 2012;28:219鈥?8.PubMed CrossRef PubMed Central
    27.Imazato S, Kuramoto A, Takahashi Y, Ebisu S, Peters MC. In vitro antibacterial effects of the dentin primer of Clearfil Protect Bond. Dent Mater. 2006;22:527鈥?2.PubMed CrossRef
    28.Schmalz G, Erg眉c眉 Z, Hiller KA. Effect of dentin on the antibacterial activity of dentin bonding agents. J Endod. 2004;30:352鈥?.PubMed CrossRef
    29.Imazato S, Walls AWG, Kuramoto A, Ebisu S. Penetration of an antibacterial dentine-bonding system into demineralized human root dentine in vitro. Eur J Oral Sci. 2002;110:168鈥?4.PubMed CrossRef
    30.Imazato S, Kaneko T, Takahashi Y, Noiri Y, Ebisu S. In vivo antibacterial effects of dentin primer incorporating MDPB. Oper Dent. 2004;29:369鈥?5.PubMed
    31.Imazato S, Kinomoto Y, Tarumi H, Ebisu S, Tay FR. Antibacterial activity and bonding characteristics of an adhesive resin containing antibacterial monomer MDPB. Dent Mater. 2003;19:313鈥?.PubMed CrossRef
    32.Li F, Chai ZG, Sun MN, Wang F, Ma S, Zhang L, et al. Anti-biofilm effect of dental adhesive with cationic monomer. J Dent Res. 2009;88:372鈥?.PubMed CrossRef
    33.Li F, Chen J, Chai Z, Zhang L, Xiao Y, Fang M, et al. Effects of a dental adhesive incorporating antibacterial monomer on the growth, adherence and membrane integrity of Streptococcus mutans. J Dent. 2009;37:289鈥?6.PubMed CrossRef
    34.Brambilla E, Ionescu A, Fadini L, Mazzoni A, Imazato S, Pashley D, et al. Influence of MDPB-containing primer on Streptococcus mutans biofilm formation in simulated class I restorations. J Adhes Dent. 2013;5:431鈥?.
    35.Xiao YH, Ma S, Chen JH, Chai ZG, Li F, Wang YJ. Antibacterial activity and bonding ability of an adhesive incorporating anantibacterial monomer DMAE-CB. Biomed Mater Res B Appl Biomater. 2009;90:813鈥?.CrossRef
    36.Imazato S, Ebi N, Takahashi Y, Kaneko T, Ebisu S, Russell RR. Antibacterial activity of bactericide-immobilized filler forresin-based restoratives. Biomaterials. 2003;24:3605鈥?.PubMed CrossRef
    37.Muller R, Eidt A, Hiller KA, Katzur V, Subat M, Schweikl H, et al. Influences of protein films on antibacterial orbacteria-repellent surface coatings in a model system usingsilicon wafers. Biomaterials. 2009;30:4921鈥?.PubMed CrossRef
    38.Cheng L, Weir MD, Zhang K, Arola DD, Zhou X, Xu HH. Dental primer and adhesive containing a new antibacterial quaternary ammonium monomer dimethylaminododecyl methacrylate. J Dent. 2013;41:345鈥?5.PubMed CrossRef PubMed Central
    39.Zhang K, Li F, Imazato S, Cheng L, Liu H, Arola DD, et al. Dual antibacterial agents of nano-silver and 12-methacryloyloxydodecylpyridinium bromide in dental adhesive to inhibit caries. J Biomed Mater Res B Appl Biomater. 2013;101:929鈥?8.PubMed CrossRef
    40.Breschi L, Mazzoni A, Ruggeri A, Cadenaro M, Di Lenarda R, De Stefano DE. Dental adhesion review: aging and stability of the bonded interface. Dent Mater. 2008;24:90鈥?01.PubMed CrossRef
    41.Hebling J, Pashley DH, Tj盲derhane L, Tay FR. Chlorhexidine arrests subclinical degradation of dentin hybrid layers invivo. J Dent Res. 2005;84:741鈥?.PubMed CrossRef
    42.Carrilho MR, Geraldeli S, Tay F, de Goes MF, Carvalho RM, Tj盲derhane L, et al. In vivo preservation of the hybrid layerbychlorhexidine. J Dent Res. 2007;86:529鈥?3.PubMed CrossRef
    43.Carrilho MR, Carvalho RM, Sousa EN, Nicolau J, Breschi L, Mazzoni A, et al. Substantivity of chlorhexidine to humandentin. Dent Mater. 2010;26:779鈥?5.PubMed CrossRef PubMed Central
    44.Zhou J, Tan J, Chen L, Li D, Tan Y. The incorporation of chlorhexidine in a two-step self-etching adhesive preserves dentin bond in vitro. J Dent. 2009;37:807鈥?2.PubMed CrossRef
    45.鈥?/div>Tezvergil-Mutluay A, Agee KA, Uchiyama T, Imazato S, Mutluay MM, Cadenaro M, et al. The inhibitory effects of quaternary ammonium methacrylates on soluble and matrix-bound MMPs. J Dent Res. 2011;90:535鈥?0. This research investigated the influences of quaternary ammonium methacrylates on MMPs and proved that these monomers have comparable MMP inhibitory activity to chlorhexidine. PubMed CrossRef PubMed Central
    46.Liu N, Li F, Chen YJ, Zhang L, Lu S, Kang JJ, et al. The inhibitory effect of a polymerisable cationic monomer on functional matrix metalloproteinases. J Dent. 2013;41:1101鈥?.PubMed CrossRef
    47.Donmez N, Belli S, Pashley DH, Tay FR. Ultrastructural correlates of in vivo/invitro bond degradation in self-etch adhesives. J Dent Res. 2005;84:355鈥?9.PubMed CrossRef
    48.鈥⑩€?/div>Bedran-Russo AK, Pauli GF, Chen SN, McAlpine J, Castellan CS, Phansalkar RS, et al. Dentin聽biomodification:鈥塻trategies, renewable resources and clinical applications. Dent Mater. 2014;30:62鈥?6. This review provides an overview of key聽dentin matrix components, targeting effects of聽biomodification聽strategies, the chemistry of聽renewable聽natural sources, and current research on their potential聽clinical聽applications. PubMed CrossRef
    49.Han B, Jaurequi J, Tang BW, Nimni ME. Proanthocyanidin: anatural crosslinking reagent for stabilizing collagenmatrices. J Biomed Mater Res A. 2003;65:118鈥?4.PubMed CrossRef
    50.Fang M, Liu R, Xiao Y, Li F, Wang D, Hou R, et al. Biomodification to dentin by a natural crosslinker improved the resin-dentin bonds. J Dent. 2012;40:458鈥?6.PubMed CrossRef
    51.Liu R, Fang M, Xiao Y, Li F, Yu L, Zhao S, et al. The effect of transient proanthocyanidins preconditioning on the cross-linking and mechanical properties of demineralized dentin. J Mater Sci Mater Med. 2011;22:2403鈥?1.PubMed CrossRef
    52.Green B, Yao X, Ganguly A, Xu C, Dusevich V, Walker MP, et al. Grape seed proanthocyanidins increase collagen biodegradation resistance in the dentin/adhesive interface when included in an adhesive. J Dent. 2010;38:908鈥?5.PubMed CrossRef PubMed Central
    53.Liu Y, Wang Y. Effect of proanthocyanidins and photo-initiators on photo-polymerization of a dental adhesive. J Dent. 2013;41:71鈥?.PubMed CrossRef PubMed Central
    54.Hechler B, Yao X, Wang Y. Proanthocyanidins alteradhesive/dentin bonding strengths when included in a bonding system. Am J Dent. 2012;25:276鈥?0.PubMed PubMed Central
    55.Epasinghe DJ, Yiu CKY, Burrow MF, Tay FR, King NM. Effectof proanthocyanidin incorporation into dental adhesiveresin on resin-dentine bond strength. J Dent. 2012;40:173鈥?0.PubMed CrossRef
    56.Liu Y, Tj盲derhane L, Breschi L, Mazzoni A, Li N, Mao J, et al. Limitations in bonding to dentin and experimental strategies to prevent bond degradation. J Dent Res. 2011;90:953鈥?8.PubMed CrossRef PubMed Central
    57.Shen C, Zhang NZ, Anusavice KJ. Fluoride and chlorhexidine release from filled resins. J Dent Res. 2010;89:1002鈥?.PubMed CrossRef PubMed Central
    58.Mukai Y, Tomiyama K, Shiiya T, Kamijo K, Fujino F, Teranaka T. Formation of inhibition layers with a newly developedfluoride-releasing all-in-one adhesive. Dent Mater J. 2005;24:172鈥?.PubMed CrossRef
    59.Torii Y, Itota T, Okamoto M, Nakabo S, Nagamine M, Inoue K. Inhibition of artificial secondary caries in root byfluoride-releasing restorative materials. Oper Dent. 2001;26:36鈥?3.PubMed
    60.Preston AJ, Mair LH, Agalamanyi EA, Higham SM. Fluoride release from aesthetic dental materials. J Oral Rehabil. 1999;26:123鈥?.PubMed CrossRef
    61.Itota T, Torii Y, Nakabo S, Tashiro Y, Konishi N, Nagamine M, et al. Effect of fluoride-releasing adhesive system on decalcified dentin. J Oral Rehabil. 2003;30:178鈥?3.PubMed CrossRef
    62.Shinohara MS, De Goes MF, Schneider LF, Ferracane JL, Pereira PN, Di Hip贸lito V, et al. Fluoride-containing adhesive: durability on dentin bonding. Dent Mater. 2009;25:1383鈥?1.PubMed CrossRef
    63.El-Deeb HA, Al Sherbiney HH, Mobarak EH. Bond durability of adhesives containing modified-monomer with/without-fluoride after aging in artificial saliva and under intrapulpal pressure simulation. Oper Dent. 2013;38:48鈥?6.PubMed CrossRef
    64.Klont B, ten Cate JM. Remineralization of bovine incisor root lesions in vitro: the role of the collagenous matrix. Caries Res. 1991;25:39鈥?5.PubMed CrossRef
    65.Kim YK, Yiu CK, Kim JR, Gu L, Kim SK, Weller RN, et al. Failure of a glass ionomer to remineralize apatite-depleted dentin. J Dent Res. 2010;89:230鈥?.PubMed CrossRef PubMed Central
    66.Liu Y, Mai S, Li N, Yiu CK, Mao J, Pashley DH, et al. Differences between top-down and bottom-up approaches in mineralizing thick, partially demineralized collagen scaffolds. Acta Biomater. 2011;7:1742鈥?1.PubMed CrossRef PubMed Central
    67.Tay FR, Pashley DH. Guided tissuere mineralisation of partially demineralised human dentine. Biomaterials. 2008;29:1127鈥?7.PubMed CrossRef
    68.Tay FR, Pashley DH. Biomimetic remineralization of resin-bonded acid-etched dentin. J Dent Res. 2009;88:719鈥?4.PubMed CrossRef PubMed Central
    69.Kim J, Arola DD, Gu L, Kim YK, Mai S, Liu Y, et al. Functional biomimetic analogs help remineralize apatite-depleted demineralized resin-infiltrated dentin via a bottom-up approach. Acta Biomater. 2010;6:2740鈥?0.PubMed CrossRef PubMed Central
    70.Niederberger M, C枚lfen H. Oriented attachment and mesocrystals: non-classical crystallization mechanisms based on nanoparticle assembly. Phys Chem Chem Phys. 2006;8:3271鈥?7.PubMed CrossRef
    71.Balooch M, Habelitz S, Kinney JH, Marshall SJ, Marshall GW. Mechanical properties of mineralized collagen fibrils as influenced by demineralization. J Struct Biol. 2008;162:404鈥?0.PubMed CrossRef PubMed Central
    72.Bertassoni LE, Habelitz S, Kinney JH, Marshall SJ, Marshall Jr GW. Biomechanical perspective on the remineralization of dentin. Caries Res. 2009;43:70鈥?.PubMed CrossRef PubMed Central
    73.Bertassoni LE, Habelitz S, Marshall SJ, Marshall JW. Mechanical recovery of dentin following remineralization in vitro-an indentation study. J Biomech. 2011;44:176鈥?1.PubMed CrossRef PubMed Central
    74.Mai S, Kim YK, Toledano M, Breschi L, Ling JQ, Pashley DH, et al. Phosphoric acid esters cannot replace polyvinylphosphonic acid as phosphoprotein analogs in biomimetic remineralization of resin-bonded dentin. Dent Mater. 2009;25:1230鈥?.PubMed CrossRef PubMed Central
    75.Mai S, Kim YK, Kim J, Yiu CK, Ling J, Pashley DH, et al. In vitro remineralization of severely compromised bonded dentin. J Dent Res. 2010;89:405鈥?0.PubMed CrossRef PubMed Central
    76.Kim J, Vaughn RM, Gu L, Rockman RA, Arola DD, Schafer TE, et al. Imperfect hybrid layers created by an aggressive one-step self-etch adhesive in primary dentin are amendable to biomimetic remineralization in vitro. J Biomed Mater Res A. 2010;93:1225鈥?4.PubMed PubMed Central
    77.Kim J, Mai S, Carrilho MR, Yiu CK, Pashley DH, Tay FR. An all-in-one adhesive does not etch beyond hybrid layers. J Dent Res. 2010;89:482鈥?.PubMed CrossRef PubMed Central
    78.Liu Y, Li N, Qi Y, Niu LN, Elshafiy S, Mao J, et al. The use of sodium trimetaphosphate as a biomimetic analog of matrix phosphoproteins for remineralization of artificial caries-like dentin. Dent Mater. 2011;27:465鈥?7.PubMed CrossRef PubMed Central
    79.Qi YP, Li N, Niu LN, Primus CM, Ling JQ, Pashley DH, et al. Remineralization of artificial dentinal caries lesions by biomimetically modified mineral trioxide aggregate. Acta Biomater. 2012;8:836鈥?2.PubMed CrossRef PubMed Central
    80.Kim YK, Mai S, Mazzoni A, Liu Y, Tezvergil-Mutluay A, Takahashi K, et al. Biomimetic remineralization as a progressive dehydration mechanism of collagen matrices-implications in the aging of resin-dentin bonds. Acta Biomater. 2010;6:3729鈥?9.PubMed CrossRef PubMed Central
    81.Ryou H, Niu LN, Dai L, Pucci CR, Arola DD, Pashley DH, et al. Effect of biomimetic remineralization on the dynamic nanomechanical properties of dentin hybrid layers. J Dent Res. 2011;90:1122鈥?.PubMed CrossRef PubMed Central
    82.鈥⑩€?/div>Niu LN, Zhang W, Pashley DH, Breschi L, Mao J, Chen JH, et al. Biomimetic remineralization of dentin. Dent Mater. 2014;30:77鈥?6. This paper reviewed the changing concepts in calcium phosphate mineralization of fibrillar collagen, and summarized the latest findings on the聽remineralization聽of resin-dentin聽bonds and artificial caries-like lesions. The problems and progress associated with the translation of a scientifically sound concept into a clinically applicable approach were also discussed. PubMed CrossRef
    83.Skrtic D, Antonucci JM, Eanes ED, Eichmiller FC, Schumacher GE. Physiological evaluation of bioactive polymeric composites based on hybrid amorphous calcium phosphates. J Biomed Mater Res B Appl Biomater. 2000;53B:381鈥?1.CrossRef
    84.Dickens SH, Flaim GM, Takagi S. Mechanical properties and biochemical activity of remineralizing resin-based Ca-PO4 cements. Dent Mater. 2003;19:558鈥?6.PubMed CrossRef
    85.Xu HHK, Sun L, Weir MD, Antonucci JM, Takagi S, Chow LC, et al. Nano dicalcium phosphate anhydrous-whisker composites with high strength and Ca and PO4 release. J Dent Res. 2006;85:722鈥?.PubMed CrossRef PubMed Central
    86.Xu HHK, Weir MD, Sun L, Takagi S, Chow LC. Effect of calcium phosphate nanoparticles on Ca-PO4 composites. J Dent Res. 2007;86:378鈥?3.PubMed CrossRef PubMed Central
    87.Br盲nnstr枚m M, Nyborg H, Str枚mberg T. Experiments with pulp capping. Oral Surg Oral Med Oral Pathol. 1979;48:347鈥?2.PubMed CrossRef
    88.Stanley HR. Criteria for standardizing and increasing credibility of direct pulp capping studies. Am J Dent. 1998;11:17鈥?4.
    89.Cox CF, Suzuki S. Re-evaluating pulp protection: calcium hydroxide liners vs. cohesive hybridization. J Am Dent Assoc. 1994;125:823鈥?1.PubMed
    90.Taira Y, Shinkai K, Suzuki M, Kato C, Katoh Y. Direct聽pulp聽capping effect with experimentally developed adhesive resin systems containing reparative dentin-promoting agents on rat聽pulp: mixed amounts of additives and their effect on wound healing. Odontology. 2011;99:135鈥?7.PubMed CrossRef
    91.Lu Y, Liu T, Li X, Li H, Pi G. Histologic evaluation of direct pulp capping with a self-etching adhesive and calcium hydroxidein beagles. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;102:78鈥?4.CrossRef
    92.Kitasako Y, Ikeda M, Tagami J. Pulpal responses to bacterial contamination following dentin bridging beneath hard-setting calcium hydroxide and self-etching adhesive resin system. Dent Traumatol. 2008;24:201鈥?.PubMed CrossRef
    93.Koliniotou-Koumpia E, Tziafas D. Pulpal responses following direct pulp capping of healthy dog teeth with dentine adhesive systems. J Dent. 2005;33:639鈥?7.PubMed CrossRef
    94.Silva GAB, Lanza LD, Lopes-J煤nior N, Moreira A, Alves JB. Direct pulp capping with a dentin bonding system in human teeth: a clinical and histological evaluation. Oper Dent. 2006;31:297鈥?07.PubMed CrossRef
  • 作者单位:Sai Ma (1)
    Lina Niu (1)
    Fang Li (1)
    Ming Fang (1)
    Ling Zhang (1)
    Franklin R. Tay (2)
    Satoshi Imazato (3)
    Jihua Chen (1)

    1. State Key Laboratory of Military Stomatology, Department of Prosthodontics, School of Stomatology, The Fourth Military Medical University, Xi鈥檃n, China
    2. Department of Endodontics, Georgia Regents University, Augusta, GA, USA
    3. Department of Biomaterials Science, Osaka University Graduate School of Dentistry, Osaka, Japan
  • 刊物类别:Oral and Maxillofacial Surgery;
  • 刊物主题:Oral and Maxillofacial Surgery;
  • 出版者:Springer International Publishing
  • ISSN:2196-3002
文摘
Esthetic restoration using resinous materials has achieved great success in the past decade.A large part of this success is attributed to the significant advances in adhesive materials. Although refinement of existing adhesive materials is still required to improve bonding reliability and reproducibility, the development of innovative adhesives with bioprotective/biopromoting functions has been recognized as an important direction for future research. Until now, significant achievements have been made in the development of adhesives that can protect the bonded interface from extrinsic bacteria- or intrinsic enzyme-induced destruction, as well as those that can promote the natural remineralization or regeneration process of the tooth tissue. In this review, the author will summarize the latest developments in these innovative bioactive adhesive materials. Keywords Dental adhesives Bioprotective Biopromoting Antibacterial MMPs Collagen cross-linking Remineralization Pulp regeneration

© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号

地址:北京市海淀区学院路29号 邮编:100083

电话:办公室:(+86 10)66554848;文献借阅、咨询服务、科技查新:66554700