Comparative analysis between endometrial proteomes of pregnant and non-pregnant ewes during the peri-implantation period
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- 作者：Haichao Zhao ; Linlin Sui ; Kai Miao ; Lei An…
- 关键词：Early pregnancy loss ; Endometrium ; Ewe ; LC ; MS/MS ; Proteome
- 刊名：Journal of Animal Science and Biotechnology
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：6
- 期：1
- 全文大小：1,937 KB
- 刊物主题：Agriculture; Biotechnology; Food Science; Animal Genetics and Genomics; Animal Physiology;
- 出版者：BioMed Central
- ISSN：2049-1891
文摘
Background Early pregnancy failure has a profound impact on both human reproductive health and animal production. 2/3 pregnancy failures occur during the peri-implantation period; however, the underlying mechanism(s) remains unclear. Well-organized modification of the endometrium to a receptive state is critical to establish pregnancy. Aberrant endometrial modification during implantation is thought to be largely responsible for early pregnancy loss.