Changes in colorectal cancer incidence rates in young and older adults in the United States: what does it tell us about screening

详细信息    查看全文

• 作者：Harland Austin (1) (3)
  S. Jane Henley (2)
  Jessica King (2)
  Lisa C. Richardson (2)
  Christie Eheman (2)
  
• 关键词：Colorectal ; Cancer ; Colonoscopy ; Incidence ; Trends
• 刊名：Cancer Causes and Control
• 出版年：2014
• 出版时间：February 2014
• 年：2014
• 卷：25
• 期：2
• 页码：191-201
• 全文大小：643 KB
• 作者单位：Harland Austin (1) (3)
  S. Jane Henley (2)
  Jessica King (2)
  Lisa C. Richardson (2)
  Christie Eheman (2)
  
  1. Rollins School of Public Health, Emory University, Atlanta, GA, USA
  3. 4770 Buford Highway NE, Mail Stop F-69, Atlanta, GA, 30341, USA
  2. Cancer Surveillance Branch, Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
  
• ISSN：1573-7225

文摘

Purpose Colorectal cancer (CRC) incidence rates have increased among young adults and have decreased among older adults. We re-evaluated these trends using more recent data covering about 96?% of the United States population. Methods Colorectal cancer incidence rates were abstracted from the National Program of Cancer Registries and the Surveillance Epidemiology and End Results analytic files for diagnosis years 1998-009. We report rates for young adults (age <50?years) and for older adults (age 50?years or older) by four race/ethnicity groupings. We examined CRC incidence rates by stage at diagnosis, tumor subsite, and state. We calculated the correlation between state-specific CRC incidence and prevalence of colonoscopy reported in the Behavioral Risk Factor Surveillance System. Results Rectal cancer incidence rates increased from 1998 through 2009 among young non-Hispanic white adults and young blacks. Among older adults, CRC incidence rates decreased among all four race/ethnicity groupings and in all states. The decline was apparent for all stages and for all subsites. States with greater decreases in CRC incidence rates had higher colonoscopy screening rates. Conclusion Rectal cancer is increasing among younger adults, for reasons largely unknown. Among older adults, CRC incidence continues to decrease, probably because of increasing uptake of colonoscopy screening. Decreases in CRC incidence are correlated with increased use of colonoscopy, indicating that CRC may be largely preventable through colonoscopy screening. Efforts to increase screening rates in underserved populations would help reduce health disparities associated with this type of cancer.