Doppler flowmetry as a tool of predictive, preventive and personalised dentistry
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  • 作者:Liudmila Yu Orekhova (1) (2)
    Anna A Barmasheva (1)
  • 关键词:Predictive periodontology ; Preventive periodontology ; Personalised periodontology ; Microcirculation ; Laser Doppler flowmetry ; Ultrasonic Doppler flowmetry ; Gingival blood flow ; Pulpal blood flow
  • 刊名:The EPMA Journal
  • 出版年:2013
  • 出版时间:December 2013
  • 年:2013
  • 卷:4
  • 期:1
  • 全文大小:254KB
  • 参考文献:1. Michaud DS, Liu Y, Meyer M, Giovannucci E, Joshipura K: Periodontal disease, tooth loss, and cancer risk in male health professionals: a prospective cohort study. / Lancet Oncol 2008, 9:550鈥?58. CrossRef
    2. Petersen PE, Bourgeois D, Ogawa H, Estupinan-Day S, Ndiaye : The global burden of oral diseases and risks to oral health. / Bull World Health Organ 2005, 83:661鈥?69.
    3. Albandar JM, Brunelle JA, Kingman A: Destructive periodontal disease in adults 30 years of age and older in the United States, 1988鈥?994. / J Periodontol 1999, 70:13鈥?9. Erratum, 70:351 CrossRef
    4. Oliver RC, Brown LJ, Loe H: Periodontal diseases in the United States population. / J Periodontol 1998, 69:269鈥?78. CrossRef
    5. Uzel NG, Teles FR, Teles RP, Song XQ, Torresyap G, Socransky SS, Haffajee AD: Microbial shifts during dental biofilm re-development in the absence of oral hygiene in periodontal health and disease. / J Clin Periodontol 2011, 38:612鈥?20. CrossRef
    6. Berezow AB, Darveau RP: Microbial shift and periodontitis. / Periodontol 2000 2011, 55:36鈥?7. CrossRef
    7. Hajishengallis G, Liang S, Payne MA, Hashim A, Jotwani R, Eskan MA, McIntosh ML, Alsam A, Kirkwood KL, Lambris JD, Darveau RP, Curtis MA: Low-abundance biofilm species orchestrates inflammatory periodontal disease through the commensal microbiota and complement. / Cell Host Microbe 2011, 10:497鈥?06. CrossRef
    8. D鈥橝iuto F, Parkar M, Andreaou G, Brett PM, Ready D, Tonetti MS: Periodontitis and atherogenesis: causal association or simple coincidence? / J Clin Periodontol 2004, 31:402鈥?11. CrossRef
    9. De Backer D, Donadello K, Taccone FS, Ospina-Tascon G, Salgado D, Vincent JL: Microcirculatory alterations: potential mechanisms and implications for therapy. / Annals of Intensive Care 2011, 1:27. CrossRef
    10. Granger DN, Rodrigues SF, Yildirim A, Senchenkova EY: Microvascular responses to cardiovascular risk factors. / Microcirculation 2010, 17:192鈥?05. CrossRef
    11. Develioglu H, Kesim B, Tuncel A: Evaluation of the marginal gingival health using laser Doppler flowmetry. / Braz Dent Journal 2006, 17:219鈥?22.
    12. Develioglu H, Ozcan G, Taner L, Ozg枚ren O: A limited and useful approach to determine proximal periodontal health. / West Indian Med J 2010, 59:215鈥?18.
    13. Gleissner C, Kempski O, Peylo S, Glatxel JH, Willershausen B: Local gingival blood flow at healthy and inflamed sites measured by laser Doppler flowmetry. / J Periodontal 2006, 77:1762鈥?771. CrossRef
    14. Fagrell B: Advances in microcirculation network evaluation: an update. / Int J Microcirc Clin Exp 1995,15(Suppl 1):34鈥?0. CrossRef
    15. Antonios TF, Kaski JC, Hasan KM, Brown SJ, Singer DR: Rarefaction of skin capillaries in patients with anginal chest pain and normal coronary arteriograms. / Eur Heart J 200l, 22:1144鈥?148. CrossRef
    16. Balas P, Pangratis N: The diagnostic investigation using vital capillary microscopy and dynamic capillaroscopy. / Clin Hemorheol Microcirc 1997, 17:371鈥?83.
    17. Scardina GA, Pisano T, Carini F, Valenza V, Messina P: Burning mouth syndrome: an evaluation of in vivo microcirculation. / J Am Dent Assoc 2008, 139:940鈥?46.
    18. Pasqui AL, Pastorelli M, Puccetti L, Beerman U, Biagi F, Camarri A, Palazzuoli A, Servi M, Bischeri D, Saletti M, Bruni F, Auteri A: Microvascular assessment in Behcet disease: videocapillaroscopic study. / Int J Tissue React 2003, 25:105鈥?15.
    19. Scardina GA, Fuc脿 G, Messina P: Microvascular characteristics of the human interdental papilla. / Anat Histol Embryol 2007, 36:266鈥?68. CrossRef
    20. Scardina GA, Messina P: Morphologic changes in the microcirculation induced by chronic smoking habit: a videocapillaroscopic study on the human gingival mucosa. / Am J Dent 2005, 18:301鈥?04.
    21. Robertson D, Williams GH (Eds): / Clinical and Translational Science: Principles of Human Research. London: Academic Press; 2008:215.
    22. van Adrichem LNA: / Laser Doppler flowmetry in microvascular surgery. Erasmus Universiteit Rotterdam; 1992. [ / PhD thesis]
    23. Cheremisinoff NP, Cheremisinoff PN: / Flow Measurement for Engineers and Scientists. New York: Marcel Dekker, Inc; 1988.
    24. Svalestad J, Hellem S, Vaagbo G, Irgens A, Thorsen E: Reproducibility of transcutaneous oximetry and laser Doppler flowmetry in facial skin and gingival tissue. / Microvasc Res 2010, 79:29鈥?3. CrossRef
    25. Maiman TH: Stimulated optical radiation in ruby. / Nature 1960, 187:493鈥?94. CrossRef
    26. Cummins HZ, Knable N, Yeh Y: Observation of diffusion broadening of Rayleigh scattered light. / Phys Rev Lett 1964, 12:150鈥?53. CrossRef
    27. Riva C, Ross B, Benedek GB: Laser Doppler measurements of blood flow in capillary tubes and retinal arteries. / Invest Ophthalmol 1972, 11:936鈥?44.
    28. Stern MD: In vivo observation of microcirculation by coherent light scattering. / Nature 1975, 254:56鈥?8. CrossRef
    29. Rotering RH Jr, Dixon JA, Holloway GA Jr, McCloskey DW: A comparison of the He-Ne laser and ultrasound Doppler systems in the determination of viability of ischemic canine intestine. / Ann Surg 1982, 196:705鈥?08. CrossRef
    30. Shiogai Y, Stefanovska A, McClintock PVE: Nonlinear dynamics of cardiovascular ageing. / Phys Rep 2010, 488:51鈥?10. CrossRef
    31. Kvietys PR, Shepherd AP, Granger DN: Laser-Doppler, H2 clearance, and microsphere estimates of mucosal blood flow. / Am J Physiol 1985, 249:G221-G227.
    32. Bonner RF, Clem TR, Bowen PD: Laser-Doppler continuous real-time monitor of pulsatile and mean blood flow in tissue microcirculation. In / Scattering Techniques Applied to Supramolecular and Nonequilibrium Systems. New York: Plenum; 1992:685鈥?02.
    33. Bonner RF, Nossal R: Model for laser Doppler measurements of blood flow in tissue. / J Opt Soc Am 1981, 20:2097鈥?107.
    34. Matthews B, Vongsavan N: Advantages and limitations of laser Doppler flow meters. / Int Endod J 1993, 26:9鈥?0. CrossRef
    35. Vongsavan N, Matthews B: Experiments in pigs on the sources of laser Doppler blood-flow signals recorded from teeth. / Arch Oral Biol 1996, 41:97鈥?03. CrossRef
    36. Emshoff R, Emshoff I, Moschen I, Strobl H: Laser Doppler flow measurements of pulpal blood flow and severity of dental injury. / Int Endod J 2004, 37:463鈥?67. CrossRef
    37. Chen E, Abbott PV: Dental pulp testing: a review. / Int J Dent 2009, 2009:365785.
    38. Gazelius B, Olgart L, Edwall B, Edwall L: Non-invasive recording of blood flow in human dental pulp. / Endod Dent Traumatol 1986, 2:219鈥?21. CrossRef
    39. Lobo EC, Nguyen SMT, Pogrel MA: The effect of exercise on pulpal and gingival blood flow in physically active and inactive subjects as assessed by laser Doppler. / Open Dent J 2012, 6:56鈥?0. CrossRef
    40. Sasano T, Kuriwada S, Sanjo D, Izumi H, Tabata T, Karita K: Acute response of periodontal ligament blood flow to external force application. / J Periodontal Res 1992, 27:301鈥?04. CrossRef
    41. Baab DA, Oberg A, Lundstrom A: Gingival blood flow and temperature changes in young humans with a history of periodontitis. / Arch Oral Biol 1990, 35:95鈥?01. CrossRef
    42. Baab DA, Oberg PA, Holloway GA: Gingival blood flow measured with a laser Doppler flowmeter. / J Periodontal Res 1986, 21:73鈥?5. CrossRef
    43. Baab DA, Oberg PA: Laser Doppler measurement of gingival blood flow in dogs with increasing and decreasing inflammation. / Arch Oral Biol 1987, 32:551鈥?55. CrossRef
    44. Hinrichs JE, LaBelle LL, Aeppli D: An evaluation of laser Doppler readings obtained from human gingival sulci. / J Periodontol 1995, 66:171鈥?76. CrossRef
    45. Sailus J, Trowbridge H, Greco M, Emling R: Sensitivity of teeth subjected to orthodontic forces [abstract]. / J Dent Res 1987, 66:No556.
    46. Boutault F, Cadenat H, Hibert PJ: Evaluation of gingival microcirculation by a laser-Doppler flowmeter. / J Craniomaxillofac Surg 1989, 17:105鈥?09. CrossRef
    47. Ketabi M, Hirsch RS: The effects of local anesthetic containing adrenaline on gingival blood flow in smokers and non-smokers. / J Clin Periodontol 1997, 24:888鈥?92. CrossRef
    48. Verdonck HW, Meijer GJ, Kessler P, Nieman FH, de Baat C, Stoelinga PJ: Assessment of bone vascularity in the anterior mandible using laser Doppler flowmetry. / Clin Oral Implants Res 2009, 20:140鈥?44. CrossRef
    49. Keremi B, Csempesz F, Vag J, Gyorfi A, Fazekas A: Blood flow in marginal gingiva as measured with laser Doppler. / Fogorv Sz 2000, 10:163鈥?68.
    50. Hoke JA, Burkes EJ, White JT, Duffy MB, Klitzman B: Blood-flow mapping of oral tissues by laser Doppler flowmetry. / Int J Oral Maxillofac Surg 1994, 23:312鈥?15. CrossRef
    51. Kerdvongbundit V, Vongsavan N, Soo-Ampon S, Phankosol P, Hasegawa A: Microcirculation of the healthy human gingiva. / Odontology 2002, 90:48鈥?1. CrossRef
    52. Donos N, D鈥橝iuto F, Retzepi M, Tonetti M: Evaluation of gingival blood flow by the use of laser Doppler flowmetry following periodontal surgery: a pilot study. / J Periodontal Res 2005, 40:129鈥?37. CrossRef
    53. Matheny JL, Jhonson DT, Vroth GI: Aging and microcirculatory dynamics in human gingiva. / J Clin Periodontol 1993, 20:471鈥?75. CrossRef
    54. Perry DA, Macdowell J, Goodis HI: Gingival Microcirculation response to tooth brushing measured by laser Doppler flowmetry. / J Periodontol 1997, 68:990鈥?95. CrossRef
    55. 脰berg PA, Hollaway G: Gingival blood flow measured with a laser Doppler flowmetry. / J Periodontol 1986, 21:73鈥?5. CrossRef
    56. Vag J, Fazekas A: Influence of restorative manipulations on the blood perfusion of human marginal gingiva as measured by laser Doppler flowmetry. / J Oral Rehabil 2002, 29:52鈥?7. CrossRef
    57. al-Wahadni A, Linden GJ, Hussey DL: Periodontal response to cantilevered and fixed-fixed resin bonded bridges. / Eur J Prosthodont Restor Dent 1999, 7:57鈥?0.
    58. Reeves WG: Restorative margin placement and periodontal health. / J Prosthet Dent 1991, 66:733鈥?36. CrossRef
    59. Kaplan ML, Jeffcoat MK, Goldhaber P: Blood flow in gingiva and alveolar bone in beagles with periodontal disease. / J Periodontal Res 1982, 17:384鈥?89. CrossRef
    60. Hock JM, Kim S: Blood flow in healed and inflamed tissue of dogs. / J Periodontal Res 1987, 22:1鈥?. CrossRef
    61. Wilder-Smith P, Frosch P: Laser Doppler flowmetry: a method for the determination of periodontal blood flow. / Dtsch Zahnarztl Z 1988, 43:994鈥?97.
    62. Kerdvongbundit V, Sirirat M, Sirikulsathean A, Kasetsuwan J, Hasegawa A: Blood flow and human periodontal status. / Odontology 2002, 90:52鈥?6. CrossRef
    63. Kerdvongbundit V, Vongsavan N, Soo-Ampon S, Hasegawa A: Microcirculation and micromorphology of healthy and inflamed gingivae. / Odontology 2003, 91:19鈥?5. CrossRef
    64. Matheny JL, Abrams H, Johnson DT, Roth GI: Microcirculatory dynamics in experimental human gingivitis. / J Clin Periodontol 1993, 20:578鈥?83. CrossRef
    65. Hinrichs JE, Jarzembinski C, Hardie N, Aeppli D: Intrasulcular laser Doppler readings before and after root planing. / J Clin Periodontol 1995, 22:817鈥?23. CrossRef
    66. Retzepi M, Tonetti M, Donos N: Gingival blood flow changes following periodontal access flap surgery using laser Doppler flowmetry. / J Clin Periodontol 2007, 34:437鈥?43. CrossRef
    67. Retzepi M, Tonetti M, Donos N: Comparison of gingival blood flow during healing of simplified papilla preservation and modified Widman flap surgery: a clinical trial using laser Doppler flowmetry. / J Clin Periodontol 2007, 34:903鈥?11. CrossRef
    68. Baab DA, Oberg PA: The effect of cigarette smoking on gingival blood flow in humans. / J Clin Periodontol 1987, 14:418鈥?24. CrossRef
    69. Mavropoulos A, Aars H, Brodin P: Hyperaemic response to cigarette smoking in healthy gingiva. / J Clin Periodontol 2003, 30:214鈥?21. CrossRef
    70. Palmer RM, Scott DA, Meekin TN, Poston RN, Odell EW, Wilson RF: Potential mechanisms of susceptibility to periodontitis in tobacco smokers. / J Periodontal Res 1999, 34:363鈥?69. CrossRef
    71. Mullally BH: The influence of tobacco smoking on the onset of periodontitis in young persons. / Tob Induc Dis 2004, 2:6. CrossRef
    72. Meekin TN, Wilson RF, Scott DA, Ide M, Palmer RM: Laser Doppler flowmeter measurement of relative gingival and forehead skin blood flow in light and heavy smokers during and after smoking. / J Clin Periodontol 2000, 27:236鈥?42. CrossRef
    73. Yamaguchi K, Nanda RS, Kawata T: Effect of orthodontic forces on blood flow in human gingiva. / Angle Orthod 1991, 61:193鈥?04.
    74. Yamaguchi K, Nanda RS: Blood flow changes in gingival tissues due to the displacement of teeth. / Angle Orthod 1992, 62:257鈥?64.
    75. Barta A, Nagy G, Csiki Z, M谩rton S, Madl茅na M: Changes in gingival blood flow during orthodontic treatment. / Central European Journal of Medicine 2010, 5:758鈥?65. CrossRef
    76. Jafarzadeh H: Laser Doppler flowmetry in endodontics: a review. / Int Endod J 2009, 42:476鈥?90. CrossRef
    77. Miron M-I, Dodenciu D, Calniceanu M, Filip LM, Todea DC: Optimization of the laser Doppler signal acquisition timing for pulp vitality evaluation. / Timisoara Medical Journal 2010, 60:44鈥?9.
    78. Gazelius B, Olgart L, Edwall B: Restored vitality in luxated teeth assessed by laser Doppler flowmeter. / Endod Dent Traumatol 1988, 4:265鈥?68. CrossRef
    79. Mesaros S, Trope M, Maixner W, Burkes EJ: Comparison of two laser Doppler systems on the measurement of blood flow of premolar teeth under different pulpal conditions. / Int Endod J 1997, 30:167鈥?74. CrossRef
    80. Gazelius B, Lindh-Str枚mberg U, Pettersson H, 脰berg PA: Laser Doppler technique鈥攁 future diagnostic tool for tooth pulp vitality. / Int Endod J 1993, 26:8鈥?. CrossRef
    81. Karayilmaz H, Kirzioglu Z: Comparison of the reliability of laser Doppler flowmetry, pulse oximetry and electric pulp tester in assessing the pulp vitality of human teeth. / J Oral Rehabil 2011, 38:340鈥?47. CrossRef
    82. Evans D, Reid J, Strang R, Stirrups D: A comparison of laser Doppler flowmetry with other methods of assessing the vitality of traumatised anterior teeth. / Endod Dent Traumatol 1999, 15:284鈥?90. CrossRef
    83. Samraj RV, Indira R, Srinivasan MR, Kumar A: Recent advances in pulp vitality testing. / Endodontology 2003, 15:14鈥?9.
    84. Fratkin RD, Kenny DJ, Johnston DH: Evaluation of a laser Doppler flowmeter to assess blood flow in human primary incisor teeth. / Pediatr Dent 1999, 21:53鈥?6.
    85. Mesaros SV, Trope M: Revascularization of traumatized teeth assessed by laser Doppler flowmetry: a case report. / Endod Dent Traumatol 1997, 13:24鈥?0. CrossRef
    86. Yanpiset K, Vongsavan N, Sigurdsson A, Trope M: Efficacy of laser Doppler flowmetry for the diagnosis of revascularization of reimplanted immature dog teeth. / Dental Traumatol 2001, 17:63鈥?0. CrossRef
    87. Emshoff R, Moschen I, Strobl H: Use of laser Doppler flowmetry to predict vitality of luxated or avulsed permanent teeth. / Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004, 98:750鈥?55. CrossRef
    88. Emshoff R, Emshoff I, Moschen I, Strobl H: Laser Doppler flowmetry of luxated permanent incisors: a receiver operator characteristic analysis. / J Oral Rehabil 2004, 31:866鈥?72. CrossRef
    89. Strobl H, Moschen I, Emshoff I, Emshoff R: Effect of luxation type on pulpal blood flow measurements: a long-term follow-up of luxated permanent maxillary incisors. / J Oral Rehabil 2005, 32:260鈥?65. CrossRef
    90. McDonald F, Pitt Ford TR: Blood flow changes in permanent maxillary canines during retraction. / Eur J Orthod 1994, 16:1鈥?. CrossRef
    91. Barwick PJ, Ramsay DS: Effect of brief intrusive force blood flow on human pulpal blood flow. / Am J Orthod Dentofacial Orthop 1996, 110:273鈥?79. CrossRef
    92. Ikawa M, Fujiwara M, Horiuchi H, Shimauchi H: The effect of short-term tooth intrusion on human pulpal blood flow measured by laser Doppler flowmetry. / Arch Oral Biol 2001, 46:781鈥?87. CrossRef
    93. Sano Y, Ikawa M, Sugawara J, Horiuchi H, Mitani H: The effect of continuous intrusive force on human pulpal blood flow. / Eur J Orthod 2002, 24:159鈥?66. CrossRef
    94. Konno Y, Daimaruya T, Iikubo M, Kanzaki R, Takahashi I, Sugawara J, Sasano T: Morphologic and hemodynamic analysis of dental pulp in dogs after molar intrusion with the skeletal anchorage system. / Am J Orthod Dentofacial Orthop 2007, 132:199鈥?07. CrossRef
    95. Babacan H, Doruk C, Bicakci AA: Pulpal blood flow changes due to rapid maxillary expansion. / Angle Orthod 2010, 80:1136鈥?140. CrossRef
    96. Stenvik A, Mjor IA: Pulp and dentine reactions to experimental tooth intrusion: a histological study of the initial changes. / Am J Orthod 1970, 57:370鈥?85. CrossRef
    97. Stenvik A, Mjor IA: The effect of experimental tooth intrusion on pulp and dentine. / Oral Surg Oral Med Oral Pathol 1971, 32:639鈥?48. CrossRef
    98. Raiden G, Missana L, Santamaria de Torres E, Kozuszko S, Pedroso R: Pulpal response to intrusive orthodontic forces. / Acta Odontol Latinoam 1998, 11:49鈥?4.
    99. Guevara MJ, McClugage SG: Effects of intrusive forces upon the microvasculature of the dental pulp. / Angle Orthod 1980, 50:129鈥?34.
    100. Fekrazad R, Katayoun KAM, Ahrari F, Tadayon N: Laser in orthodontics. In / Principles in Contemporary Orthodontics. Edited by: Silvano N. Rijeka: InTech; 2011:129鈥?80. doi:10.5772/20204
    101. Roy E, Alliot-Licht B, Dajean-Trutaud S, Fraysse C, Jean A, Armengol V: Evaluation of the ability of laser Doppler flowmetry for the assessment of pulp vitality in general dental practice. / Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008, 106:615鈥?20. CrossRef
    102. Ikawa M, Komatsu H, Ikawa K, Mayanagi H, Shimauchi H: Age-related changes in the human pulpal blood flow measured by laser Doppler flowmetry. / Dent Traumatol 2003, 19:36鈥?0. CrossRef
    103. Firestone AR, Wheatley AM, Thuer UW: Measurement of blood perfusion in the dental pulp with laser Doppler flowmetry. / Int J Microcirc Clin Exp 1997, 17:298鈥?04. CrossRef
    104. Kaplan EN, Vistnes LM: The Doppler flow meter. / Calif Med 1972, 116:57鈥?8.
    105. Atkinson P, Wells PN: Pulse-Doppler ultrasound and its clinical application. / Yale J Biol Med 1977, 50:367鈥?73.
    106. Postema M, Gilja OH: Contrast-enhanced and targeted ultrasound. / World J Gastroenterol 2011, 17:28鈥?1. CrossRef
    107. Nimura Y, Matsuo H, Hayashi T, Kitabatake A, Mochizuki S: Studies on arterial flow patterns - instantaneous velocity spectrums and their phasic changes - with directional ultrasonic Doppler technique. / Br Heart J 1974, 36:899鈥?07. CrossRef
    108. Al Turk M, Metcalf WK: A study of superficial palmar arteries using the Doppler ultrasonic flowmeter. / J Anat 1984, 138:27鈥?2.
    109. Krechina EK, Belorukov VV: Artemisia absinthium L. in complex treatment of inflammatory periodontal disease. / Stomatologiia (Mosk) 2012, 91:22鈥?4. (Russian)
    110. Dzgoeva MG: Parodontal microhemodynamics status in patients with vascular dystonias. / Stomatologiia (Mosk) 2007, 86:6鈥?0. (Russian)
    111. Krechina EK, Rakhimova EN: Gingival tissue blood circulation in health and parodontal diseases as assessed by ultrasonic dopplerography. / Stomatologiia (Mosk) 2005, 84:24鈥?7. (Russian)
    112. Barmasheva AA, Orekhova LY, Shlyakhto EV, Goodkova AI: Microcirculation changes in the oral mucosa in patients with chronic heart failure [abstract]. / Eur J Heart Fail 2010,9(suppl. 1):S57.
    113. Musaeva R, Barmasheva A, Orekchova L: Periodontal condition and microcirculation in patients with different number of metabolic syndrome components [abstract]. / J Clinical Periodontology 2012,39(Suppl. 13s):115.
    114. Kozlov VA, Artyushenko NK, Shalack OV, Vasiliev AV, Girina MB, Girin II, Morozova EA, Monastirenko AA: / Dopplerografiya v ocenke sostoyaniya gemodynamici v tkanyax shei, lica I polosti rta v norme i pri nekotori褏 patologicheskix sostoyaniyax . St. Petersburg: Medicinskaya Akademiya poslediplomnogo obrazovaniya; 2000:31.
  • 作者单位:Liudmila Yu Orekhova (1) (2)
    Anna A Barmasheva (1)

    1. Therapeutic Dentistry Department, I.P. Pavlov Saint-Petersburg State Medical University, 6/8 Lev Tolstoy Street, Saint Petersburg, 197022, Russia
    2. City Periodontal Center 鈥楶AKS鈥? 27 Dobrolubova Prospect, Saint-Petersburg, 197198, Russia
文摘
Periodontal lesions are considered a major problem in the global burden of oral diseases due to their high frequency and negative impact on quality of life. Periodontal inflammation is accomplished by a breakdown of microcirculatory function. Early detection of gingival microvessel dysfunction helps diagnose and prevent the progression of initial periodontal pathology. Doppler flowmetry is a useful tool in the diagnosis, monitoring, prognosis and management of periodontal patients which allows access not only of gingival blood flow but also of pulpal microcirculation. Doppler flowmeters might help to realise the ultimate target of predictive, preventive and personalised periodontology tailored with respect to the particular patient. This article highlights the main working principles of laser Doppler flowmeters and the ultrasonic Doppler flowmeters. The advances in blood flow measurement by ultrasonic flowmetry are discussed.

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