Comparison of genomic and amino acid sequences of eight Japanese encephalitis virus isolates from bats

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• 作者：Shan Liu (1)
  Xing Li (1)
  Zhiyong Chen (1)
  Yixiong Chen (1)
  Qionghua Zhang (1)
  Yuxue Liao (1)
  Jie Zhou (1)
  Xuemei Ke (1)
  Lizhen Ma (1)
  Jianpeng Xiao (1)
  Yi Wu (2)
  Zhong Chen (3)
  Junhua Zhou (1)
  Xueyan Zheng (1)
  Jiandong Li (1)
  Qing Chen (1)
  
• 刊名：Archives of Virology
• 出版年：2013
• 出版时间：December 2013
• 年：2013
• 卷：158
• 期：12
• 页码：2543-2552
• 全文大小：
• 作者单位：Shan Liu (1)
  Xing Li (1)
  Zhiyong Chen (1)
  Yixiong Chen (1)
  Qionghua Zhang (1)
  Yuxue Liao (1)
  Jie Zhou (1)
  Xuemei Ke (1)
  Lizhen Ma (1)
  Jianpeng Xiao (1)
  Yi Wu (2)
  Zhong Chen (3)
  Junhua Zhou (1)
  Xueyan Zheng (1)
  Jiandong Li (1)
  Qing Chen (1)
  
  1. Department of Epidemiology, School of Public Health and Tropical Medicine, Southern Medical University, 1838 Guangzhou North Road, Guangzhou, 510515, Guangdong, China
  2. College of Life Science, Guangzhou University, Guangzhou, 510006, Guangdong, China
  3. College of Life Science, Hainan Normal University, Haikou, 571158, Hainan, China
  
• ISSN：1432-8798

文摘

We compared nucleotide and deduced amino acid sequences of eight Japanese encephalitis virus (JEV) isolates derived from bats in China. We also compared the bat JEV isolates with other JEV isolates available from GenBank to determine their genetic similarity. We found a high genetic homogeneity among the bat JEVs isolated in different geographical areas from various bat species at different time periods. All eight bat JEV isolates belonged to genotype III. The mean evolutionary rate of bat JEV isolates was lower than those of isolates of other origin, but this difference was not statistically significant. Based on these results, we presume that the bat JEV isolates might be evolutionarily conserved. The eight bat JEV isolates were phylogenetically similar to mosquito BN19 and human Liyujie isolates of JEV. These results indicate that bats might be involved in natural cycle of JEV.