Relationship between red blood cell transfusion requirements and severity of renal disease during the acute stage of hemolytic uremic syndrome

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• 作者：Carlos J. Cobe?as ; Paula S. Bresso ; Laura L. Lombardi…
• 关键词：Hemolytic uremic syndrome ; Microangiopathic hemolytic anemia ; Red blood cell transfusions ; Lactic dehydrogenase levels ; Renal disease
• 刊名：Pediatric Nephrology
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：30
• 期：12
• 页码：2115-2119
• 全文大小：248 KB
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• 作者单位：Carlos J. Cobe?as (1)
  Paula S. Bresso (1)
  Laura L. Lombardi (1)
  Oscar R. Amoreo (1)
  Javier D. Ruscasso (1)
  Ana P. Spizzirri (1)
  ?ngela del C. Suarez (1)
  Javier H. Zalba (1)
  Ricardo C. Rahman (1)
  Paula Risso (2)
  
  1. Hospital de Ni?os “Sup. Sor María Ludovica- La Plata, Buenos Aires, Argentina
  2. Cátedra de Bioestadística Bayesiana y Clásica, Carrera de Microbiología Clínica e Industrial, Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, La Plata, Buenos Aires, Argentina
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Pediatrics
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1432-198X

文摘

Background We performed a retrospective evaluation of patients with diarrhea-associated hemolytic uremic syndrome (D + HUS) with the aims of: (1) determining the rate of red blood cell (RBC) transfusions; (2) establishing the relationship between need for RBC transfusion and severity of renal involvement; (3) determining whether precise measurements of lactic dehydrogenase (LDH) levels can predict the rate of hemolysis and severity of renal disease.