Die extrapulmonalen Auswirkungen der Lungenüberblähung bei COPD

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• 作者：PD Dr. H. Watz
• 关键词：SchlüsselwörterLungenerkrankung ; Chronische obstruktive Lungenerkrankung ; Herzfunktionstest ; Belastungsintoleranz ; Skelettmuskulatur
• 刊名：Der Pneumologe
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：14
• 期：1
• 页码：20-23
• 全文大小：
• 刊物主题：Pneumology/Respiratory System; Medicine/Public Health, general; Allergology; Internal Medicine; Infectious Diseases; Oncology;
• 出版者：Springer Medizin
• ISSN：1613-6055
• 卷排序：14

文摘

Cardiac dysfunction and skeletal muscle dysfunction are extrapulmonary consequences of lung hyperinflation in chronic obstructive pulmonary disease (COPD). Several studies demonstrated that lung hyperinflation is related to an underfilling of the heart, which in turn leads to a reduced cardiac output and is associated with a further worsening of exercise intolerance in COPD. Interventional studies showed that cardiac function can be improved by interventional measures for reduction of lung hyperinflation. Skeletal muscle deconditioning due to exercise intolerance is an indirect consequence of lung hyperinflation in COPD.