Low B and T lymphocyte attenuator expression on CD4+ T cells in the early stage of sepsis is associated with the severity and mortality of septic patients: a prospective cohort study

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• 作者：Rui Shao ; Chun-Sheng Li ; Yingying Fang ; Lianxing Zhao ; Chenchen Hang
• 刊名：Critical Care
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：19
• 期：1
• 全文大小：1,304 KB
• 刊物主题：Intensive / Critical Care Medicine; Emergency Medicine;
• 出版者：BioMed Central
• ISSN：1364-8535

文摘

Introduction B and T lymphocyte attenuator (BTLA) is an inhibitory receptor, whose primary role in CD4+ T cell is thought to inhibit cytokine production. We explore BTLA expression on CD4+ T cells in healthy controls and septic patients, and assess the correlation of BTLA expression on CD4+ T cells in the early stage of sepsis with the severity and mortality of septic patients in the emergency department (ED).