A square pyramidal copper(II) complex of a Schiff base ligand: synthesis, crystal structure, antibacterial and DNA interaction studies

详细信息    查看全文

• 作者：Kalyanmoy Jana ; Tithi Maity ; Tufan Singha Mahapatra…
• 刊名：Transition Metal Chemistry
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：42
• 期：1
• 页码：69-78
• 全文大小：
• 刊物类别：Chemistry and Materials Science
• 刊物主题：Catalysis; Physical Chemistry; Inorganic Chemistry; Organometallic Chemistry;
• 出版者：Springer International Publishing
• ISSN：1572-901X
• 卷排序：42

文摘

A mononuclear Cu(II) complex [Cu(L)Cl<sub>2sub>] has been synthesized from a tridentate Schiff base ligand, piperidin-2-ylmethyl-pyridin-2-ylmethylene-amine (L). The single-crystal X-ray structure of the complex shows a square pyramidal geometry. The complex was tested against several bacteria and showed good antibacterial activities against almost all of the bacteria. The interactions of the title complex with calf thymus DNA (CT-DNA) have been investigated by electronic absorption and fluorescence spectroscopy, showing that the complex interacts with CT-DNA via partial intercalation.