The effects of cognitive reappraisal following retrieval-procedures designed to destabilize alcohol memories in high-risk drinkers
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  • 作者:Tiffany Hon ; Ravi K. Das ; Sunjeev K. Kamboj
  • 关键词:Addiction ; Alcohol ; Reconsolidation ; Memory ; Reappraisal ; Cognitive therapy ; Behavioural therapy ; Craving ; Alcohol fluency
  • 刊名:Psychopharmacology
  • 出版年:2016
  • 出版时间:March 2016
  • 年:2016
  • 卷:233
  • 期:5
  • 页码:851-861
  • 全文大小:421 KB
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  • 作者单位:Tiffany Hon (1)
    Ravi K. Das (1)
    Sunjeev K. Kamboj (1)

    1. Clinical Psychopharmacology Unit, Research Department of Clinical, Educational and Health Psychology, University College London, London, WC1E 6BT, UK
  • 刊物类别:Biomedical and Life Sciences
  • 刊物主题:Biomedicine
    Pharmacology and Toxicology
    Psychiatry
  • 出版者:Springer Berlin / Heidelberg
  • ISSN:1432-2072
文摘
Rationale Addiction is a disorder of motivational learning and memory. Maladaptive motivational memories linking drug-associated stimuli to drug seeking are formed over hundreds of reinforcement trials and accompanied by aberrant neuroadaptation in the mesocorticolimbic reward system. Such memories are resistant to extinction. However, the discovery of retrieval-dependent memory plasticity has opened up the possibility of permanent modification of established (long-term) memories during ‘reconsolidation’.

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