Simultaneous and sequential hemorrhage of multiple cerebral cavernous malformations: a case report

详细信息    查看全文

• 作者：Nundia Louis ; Robert Marsh
• 关键词：Angioma ; Cavernoma ; Cavernous malformation ; Hemorrhage ; Hypertension
• 刊名：Journal of Medical Case Reports
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：10
• 期：1
• 全文大小：1,280 KB
• 参考文献：1.Cunningham K, Uchida Y, O’Donnell E, Claudio E, Li W, Soneji K, et al. Conditional deletion of Ccm2 causes hemorrhage in the adult brain: a mouse model of human cerebral cavernous malformations. Hum Mol Genet. 2011;20:3198–206.PubMedCentral CrossRef PubMed
  2.Little J, Awad I, Jones S, Ebrahim Z. Vascular pressure and cortical blood flow in cavernous angioma of the brain. J Neurosurg. 1990;73:555–9.CrossRef PubMed
  3.Riant F, Bergametti F, Ayrignac X, Boulday G, Tournier-Lasserve E. Recent insights into cerebral cavernous malformations: the molecular genetics of CCM. FEBS J. 2010;277:1070–5.CrossRef PubMed
  4.Robinson JR, Awad IA, Little JR. Natural history of the cavernous angioma. J Neurosurg. 1991;75:709–14.CrossRef PubMed
  5.Leblanc GG, Golanov E, Awad IA, Young WL. Biology of vascular malformations of the brain. Stroke. 2009;40:e694–702.PubMedCentral CrossRef PubMed
  6.Kivelev J, Niemela M, Hernesniemi J. Characteristics of cavernomas of the brain and spine. J Clin Neurosci. 2012;19:643–8.CrossRef PubMed
  7.Panciani PP, Agnoletti A, Fornaro R, Fontanella M, Ducati A. Multiple cavernomas of the brain: simultaneous hemorrhage of two lesions in a non-familial form. Turk Neurosurg. 2012;22:671–4.PubMed
  8.Riant F, Bergametti F, Fournier HD, Chapon F, Michalak-Provost S, Cecillon M. CCM3 mutations are associated with early-onset cerebral hemorrhage and multiple meningiomas. Mol Syndromol. 2013;4:165–72.PubMedCentral PubMed
  9.Chanda A, Nanda A. Multiple cavernomas of brain presenting with simultaneous hemorrhage in two lesions: a case report. Surg Neurol. 2002;57(5):340–4.CrossRef PubMed
  10.El Asri AC, Derraz S, Gazzaz M, El Mostarchid B. Simultaneous bleeding of supratentorial and infratentorial cavernomas. Headache. 2015;55(5):680–1. doi:10.​1111/​head.​12391 .CrossRef PubMed
  11.Steinberg GK, Chang SD, Gewirtz RJ, Lopez JR. Microsurgical resection of brainstem, thalamic, and basal ganglia angiographically occult vascular malformations. Neurosurgery. 2000;46:260–70.CrossRef PubMed
  12.Del Curling JO, Kelly Jr DL, Elster AD, Craven TE. An analysis of the natural history of cavernous angiomas. J Neurosurg. 1991;75:702–8.CrossRef PubMed
  13.Kondziolka D, Lunsford L, Kestle J. The natural history of cerebral cavernous malformations. J Neurosurg. 1995;83:820–4.CrossRef PubMed
  14.Shi C, Shenkar R, Batjer HH, Check IJ, Awad IA. Oligoclonal immune response in cerebral cavernous malformations. J Neurosurg. 2007;107:1023–6.CrossRef PubMed
  15.Choquet H, Nelson J, Pawlikowska L, McCulloch C, Akers A, Baca B, et al. Association of cardiovascular risk factors with disease severity in cerebral cavernous malformation type 1 subjects with common Hispanic mutation. Cerebrovasc Dis. 2014;37:57–63.PubMedCentral CrossRef PubMed
  16.Kontos HA, Wei EP, Navari RM, Levasseur JE, Rosenblum WI, Patterson Jr JL. Responses of cerebral arteries and arterioles to acute hypotension and hypertension. Am J Physiol. 1978;234:H371–83.PubMed
  17.Mackenzie ET, Strandgaard S, Graham DI, Jones JV, Harper AM, Farrar JK. Effects of acutely induced hypertension in cats on pial arteriolar caliber, local cerebral flow, and the blood-barrier. Circ Res. 1976;39:33–41.CrossRef PubMed
  18.Landau J, Davis E. Capillary thinning and high capillary blood-pressure in hypertension. Lancet. 1957;269:1327–30.CrossRef
  19.Williams SA, Boolell M, MacGregor GA, Smaje LH, Wasserman SM, Tooke JE. Capillary hypertension and abnormal pressure dynamics in patients with essential hypertension. Clin Sci (Lond). 1990;79:5–8.CrossRef
  20.Noon JP, Walker BR, Webb DJ, Shore AC, Holton DW, Edwards HV, et al. Impaired microvascular dilatation and capillary rarefaction in young adults with a predisposition to high blood pressure. J Clin Invest. 1997;99:1873–9.PubMedCentral CrossRef PubMed
  21.Jamous MA, Nagahiro S, Kitazato KT, Tamura T, Aziz HA, Shono M, et al. Endothelial injury and inflammatory response induced by hemodynamic changes preceding intracranial aneurysm formation: experimental study in rats. J Neurosurg. 2007;107(2):405–11.CrossRef PubMed
  22.UCAS Japan Investigators, Morita A, Kirino T, Hashi K, Aoki N, Fukuhara S, et al. The natural course of unruptured cerebral aneurysms in a Japanese cohort. N Engl J Med. 2012;366:2474–82.CrossRef
  23.Ortiz R, Stefanski M, Rosenwasser R, Veznedaroglu E. Cigarette smoking is a risk factor for recurrence of aneurysms treated by endosaccular occlusion. J Neurosurg. 2008;108:672–5.CrossRef PubMed
  24.Rinkel GJ. Natural history, epidemiology and screening of unruptured intracranial aneurysms. J Neuroradiol. 2008;35:99–103.CrossRef PubMed
  25.Taylor CL, Yuan Z, Selman WR, Ratcheson RA, Rimm AA. Cerebral arterial aneurysm formation and rupture in 20,767 elderly patients: hypertension and other risk factors. J Neurosurg. 1995;83:812–9.CrossRef PubMed
  26.Hosaka K, Hoh BL. Inflammation and cerebral aneurysms. Transl Stroke Res. 2014;2:190–8.CrossRef
  
• 作者单位：Nundia Louis (1)
  Robert Marsh (1)
  
  1. Department of Neurosurgery, Cabell Huntington Hospital, Marshall University, 1600 Medical Center Drive, Huntington, WV, 25701, USA
  
• 刊物主题：Medicine/Public Health, general; General Practice / Family Medicine; Public Health; Primary Care Medicine;
• 出版者：BioMed Central
• ISSN：1752-1947

文摘

Background The etiology of cerebral cavernous malformation hemorrhage is not well understood. Causative physiologic parameters preceding hemorrhagic cavernous malformation events are often not reported. We present a case of an individual with sequential simultaneous hemorrhages in multiple cerebral cavernous malformations with a new onset diagnosis of hypertension.