Comparison in the incidence of anorectal malformations between a first- and third-world referral center

详细信息    查看全文

• 作者：Andre P. Theron ; Giulia Brisighelli ; Anne E. Theron…
• 关键词：Anorectal malformation ; Incidence ; South Africa ; Italy
• 刊名：Pediatric Surgery International
• 出版年：2015
• 出版时间：August 2015
• 年：2015
• 卷：31
• 期：8
• 页码：759-764
• 全文大小：378 KB
• 参考文献：1.Moore SW, Alexander A, Sidler D, Alves J, Hadley GP, Numanoglu A, Banieghbal B, Chitnis M, Birabwa-Male D, Mbuwayesango B, Hesse A, Lakhoo K (2008) The spectrum of anorectal malformations in Africa. Pediatr Surg Int 24(6):677鈥?83. doi:10.鈥?007/鈥媠00383-008-2131-y PubMed View Article
  2.Moore SW, Sidler D, Hadley GP (2008) Anorectal malformations in Africa. SAJS 43(4):174鈥?75
  3.International Clearing House for Birth Defects Surveillance and Research (2015) Annual Report 2011: with data for 2009. http://鈥媤ww.鈥媔cbdsr.鈥媜rg/鈥媐ilebank/鈥媎ocuments/鈥媋r2005/鈥婻eport2011.鈥媝df . Accessed 20 May 2015
  4.International Clearinghouse Birth Defects Surveillance and Research (2007) Annual Report 2007: with data for 2005. The International Centre on Birth Defects鈥擨CBDSR Centre, Via Carlo Mirabello 19, 00195 Roma, Italy
  5.Cuschieri A, Group EW (2001) Descriptive epidemiology of isolated anal anomalies: a survey of 4.6 million births in Europe. Am J Med Genet 103(3):207鈥?15View Article
  6.Lowry RB, Sibbald B, Bedard T (2007) Stability of prevalence rates of anorectal malformations in the Alberta Congenital Anomalies Surveillance System 1990鈥?004. J Pediatr Surg 42(8):1417鈥?421. doi:10.鈥?016/鈥媕.鈥媕pedsurg.鈥?007.鈥?3.鈥?45 PubMed View Article
  7.Theron A, Loveland J (2014) Birth Prevalence of Anorectal Malformation in the Referral Area for the University of the Witwatersrand Tertiary Hospitals, South Africa. Epn J Pediatr Surg Off J Austrian Assoc Pediatr Surg Zeitschrift fur Kinderchirurgie
  8.Marcelis C, de Blaauw I, Brunner H (2011) Chromosomal anomalies in the etiology of anorectal malformations: a review. Am J Med Genet A 155A(11):2692鈥?704. doi:10.鈥?002/鈥媋jmg.鈥媋.鈥?4253 PubMed View Article
  9.Holschneider A, Hutson J, Pena A, Beket E, Chatterjee S, Coran A, Davies M, Georgeson K, Grosfeld J, Gupta D, Iwai N, Kluth D, Martucciello G, Moore S, Rintala R, Smith ED, Sripathi DV, Stephens D, Sen S, Ure B, Grasshoff S, Boemers T, Murphy F, Soylet Y, Dubbers M, Kunst M (2005) Preliminary report on the International Conference for the Development of Standards for the Treatment of Anorectal Malformations. J Pediatr Surg 40(10):1521鈥?526. doi:10.鈥?016/鈥媕.鈥媕pedsurg.鈥?005.鈥?8.鈥?02 PubMed View Article
  10.Nah SA, Ong CC, Lakshmi NK, Yap TL, Jacobsen AS, Low Y (2012) Anomalies associated with anorectal malformations according to the Krickenbeck anatomic classification. J Pediatr Surg 47(12):2273鈥?278. doi:10.鈥?016/鈥媕.鈥媕pedsurg.鈥?012.鈥?9.鈥?17 PubMed View Article
  11.Levitt MA, Pena A (2007) Anorectal malformations. Orphanet J Rare Dis 2:33. doi:10.鈥?186/鈥?750-1172-2-33 PubMed Central PubMed View Article
  12.Abrams AL, Opiyo N, Cotton M, Crowley S, Okebe J, Wiysonge CS (2011) Supporting registration of child-focused clinical trials in Africa: the Child Strategy Project. SAMJ 101:804PubMed
  13.Connor M, Bryerb A (2013) Stroke in South Africa. South African Medical Research Council. http://鈥媤ww.鈥媘rc.鈥媋c.鈥媧a/鈥媍hronic/鈥媍dl1995-2005.鈥媓tm . Accessed 25 May 2015
  14.Taylor AL, Wright JT (2005) Importance of race/ethnicity in clinical trials: lessons From the African-American heart failure trial (A-HeFT), the African-American study of kidney disease and hypertension (AASK), and the antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT). Circulation 112(23):3654鈥?666. doi:10.鈥?161/鈥媍irculationaha.鈥?05.鈥?40443 PubMed View Article
  15.Moore SW, Sidler D, Hadley GP (2005) Anorectal malformations in Africa 43(4):174鈥?75
  16.Ekenze SO, Ajuzieogu OV, Nwomeh BC (2015) Neonatal surgery in Africa: a systematic review and meta-analysis of challenges of management and outcome. Lancet 385:S35. doi:10.鈥?016/鈥婼0140-6736(15)60830-3 View Article
  17.Liang Y, Shen D, Cai W (2008) Two coding single nucleotide polymorphisms in the SALL1 gene in Townes鈥揃rocks syndrome: a case report and review of the literature. J Pediatr Surg 43(2):391鈥?93. doi:10.鈥?016/鈥媕.鈥媕pedsurg.鈥?007.鈥?9.鈥?79 PubMed View Article
  18.Hagan DM, Ross AJ, Strachan T, Lynch SA, Ruiz-Perez V, Wang YM, Scambler P, Custard E, Reardon W, Hassan S, Nixon P, Papapetrou C, Winter RM, Edwards Y, Morrison K, Barrow M, Cordier-Alex MP, Correia P, Galvin-Parton PA, Gaskill S, Gaskin KJ, Garcia-Minaur S, Gereige R, Hayward R, Homfray T (2000) Mutation analysis and embryonic expression of the HLXB9 Currarino syndrome gene. Am J Hum Genet 66(5):1504鈥?515PubMed Central PubMed View Article
  19.Wijers CHW, van Rooij IALM, Marcelis CLM, Brunner HG, de Blaauw I, Roeleveld N (2014) Genetic and nongenetic etiology of nonsyndromic anorectal malformations: a systematic review. Birth Defects Res C Embryo Today 102(4):382鈥?00. doi:10.鈥?002/鈥媌drc.鈥?1068 PubMed View Article
  20.Zwink N, Jenetzky E, Brenner H (2011) Parental risk factors and anorectal malformations: systematic review and meta-analysis. Orphanet J rare Dis 6:25. doi:10.鈥?186/鈥?750-1172-6-25 PubMed Central PubMed View Article
  21.van Rooij IA, Wijers CH, Rieu PN, Hendriks HS, Brouwers MM, Knoers NV, de Blaauw I, Roeleveld N (2010) Maternal and paternal risk factors for anorectal malformations: a Dutch case鈥揷ontrol study. Birth Defects Res A 88(3):152鈥?58. doi:10.鈥?002/鈥媌dra.鈥?0649
  22.Wijers CH, de Blaauw I, Marcelis CL, Wijnen RM, Brunner H, Midrio P, Gamba P, Clementi M, Jenetzky E, Zwink N, Reutter H, Bartels E, Grasshoff-Derr S, Holland-Cunz S, Hosie S, Marzheuser S, Schmiedeke E, Cretolle C, Sarnacki S, Levitt MA, Knoers NV, Roeleveld N, van Rooij IA (2010) Research perspectives in the etiology of congenital anorectal malformations using data of the International Consortium on Anorectal Malformations: evidence for risk factors across different populations. Pediatr Surg Int 26(11):1093鈥?099. doi:10.鈥?007/鈥媠00383-010-2688-0 PubMed Central PubMed View Article
  23.Wijers CHW, Rooij I, Bakker MK, Marcelis CLM, Addor MC, Barisic I, B茅res J, Bianca S, Bianchi F, Calzolari E, Greenlees R, Lelong N, Latos-Bielenska A, Dias CM, McDonnell R, Mullaney C, Nelen V, O鈥橫ahony M, Queisser-Luft A, Rankin J, de Zymak-Zakutnia N, Blaauw I, de Roeleveld N, Walle HEK (2013) Anorectal malformations and pregnancy-related disorders: a registry-based case鈥揷ontrol study in 17 European regions. BJOG 120(9):1066鈥?074. doi:10.鈥?111/鈥?471-0528.鈥?2235 PubMed View Article
  24.de Blaauw I, Wijers CHW, Schmiedeke E, Holland-Cunz S, Gamba P, Marcelis CLM, Reutter H, Aminoff D, Schipper M, Schwarzer N, Grasshoff-Derr S, Midrio P, Jenetzky E, van Rooij IALM (2013) First results of a European multi-center registry of patients with anorectal malformations. J Pediatr Surg 48(12):2530鈥?535. doi:10.鈥?016/鈥媕.鈥媕pedsurg.鈥?013.鈥?7.鈥?22 PubMed View Article
  25.Beudeker N, Broadis E, Borgstein E, Heij HA (2013) The hidden mortality of imperforate anus. Afr J Paediatr Surg 10(4):302鈥?06. doi:10.鈥?103/鈥?189-6725.鈥?25417 PubMed View Article
  26.Sinha SK, Kanojia RP, Wakhlu A, Rawat JD, Kureel SN, Tandon RK (2008) Delayed presentation of anorectal malformations. J Indian Assoc Pediatr Surg 13(2):64鈥?8. doi:10.鈥?103/鈥?971-9261.鈥?3023 PubMed Central PubMed View Article
  27.Statovci S, Graj莽evci S, Berisha M, 脟eku G, Ademaj I, Ukeperaj K (2015) Late diagnosis of anorectal malformations in children. Surg Sci 6:143鈥?48. doi:10.鈥?236/鈥媠s.鈥?015.鈥?3023 View Article
  28.Benzies KM (2008) Advanced maternal age: are decisions about the timing of child-bearing a failure to understand the risks? CMAJ 178(2):183鈥?84. doi:10.鈥?503/鈥媍maj.鈥?71577 PubMed Central PubMed View Article
  29.Harris B, Goudge J, Ataguba JE, McIntyre D, Nxumalo N, Jikwana S, Chersich M (2011) Inequities in access to health care in South Africa. J Public Health Pol 32(S1):S102鈥揝123View Article
  30.Nevhatalu N (2014) Improving patient referral processes through electronic health record system: a case study of rural hospitals in Limpopo province. UNISA, South Africa
  31.Wilson BE, Etheridge CE, Soundappan SVS, Holland AJA (2010) Delayed diagnosis of anorectal malformations: are current guidelines sufficient? J Paediatr Child Health 46(5):268鈥?72. doi:10.鈥?111/鈥媕.鈥?440-1754.鈥?009.鈥?1683.鈥媥 PubMed View Article
  32.Tareen F, Coyle D, Aworanti OM, Gillick J (2013) Delayed diagnosis of anorectal malformation鈥揳 persistent problem. Ir Med J 106(8):238鈥?40PubMed
  33.Goudge J, Gilson L, Russell S, Gumede T, Mills A (2009) Affordability, availability and acceptability barriers to health care for the chronically ill: longitudinal case studies from South Africa. BMC Health Serv Res 9:75. doi:10.鈥?186/鈥?472-6963-9-75 PubMed Central PubMed View Article
  34.Mojaki ME, Basu D, Letskokgohka ME, Govender M (2011) Referral steps in district health system are side-stepped. SAMJ 101:109PubMed
  35.Richards DB, Jacquet GA (2012) Analysis of referral appropriateness in the Western Cape, South Africa, and implications for resource allocation. Afr J Emerg Med 2(2):53鈥?8. doi:10.鈥?016/鈥媕.鈥媋fjem.鈥?012.鈥?3.鈥?06 View Article
  36.Hughes GD, Aboyade OM, Clark BL, Puoane TR (2013) The prevalence of traditional herbal medicine use among hypertensives living in South African communities. BMC Complement Altern Med 13:38. doi:10.鈥?186/鈥?472-6882-13-38 PubMed Central PubMed View Article
  37.Sorsdahl K, Stein DJ, Grimsrud A, Seedat S, Flisher AJ, Williams DR, Myer L (2009) Traditional healers in the treatment of common mental disorders in South Africa. J Nerv Ment Dis 197(6):434鈥?41. doi:10.鈥?097/鈥婲MD.鈥?b013e3181a61dbc鈥?/span> PubMed Central PubMed View Article
  
• 作者单位：Andre P. Theron (1)
  Giulia Brisighelli (2)
  Anne E. Theron (3)
  Ernesto Leva (2)
  Alp Numanoglu (1)
  
  1. Department of Pediatric Surgery, Red Cross War Memorial Children鈥檚 Hospital, University of Cape Town, 6th Floor ICH Building, Klipfontein Road, Rondebosch, 7700, Cape Town, Republic of South Africa
  2. Department of Pediatric Surgery, Fondazione IRCCS Ca鈥?Granda Ospedale Maggiore Policlinico, Milan, Italy
  3. Department of Physiology, University of Pretoria, Pretoria, Republic of South Africa
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Pediatrics
  Surgery
  Pediatric Surgery
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1437-9813

文摘

Purpose Aim of study was to evaluate the differences in incidence and presentation of anorectal malformations (ARMs) between selected Pediatric Surgery Divisions in the Republic of South Africa (ZAR) and Italy. Methods A retrospective cohort study involved analysis of clinical records of patients with ARM born between 2005 and 2012. Type of ARM, maternal age, birth weight, gestational age, presence of associated anomalies and delayed diagnosis were analyzed. Results 335 patients were included in this study. Of note, statistically significant differences between the African and European patient groups were observed in a male predominance in the ZAR patient population. In addition, female recto-perineal fistulas were diagnosed in significantly more Italian patients than in ZAR. Furthermore, a more advanced maternal age and a lower gestational age was noted in the European cohort with a minimal delay in initial diagnosis as opposed to the African counterpart. Both centers reported recto-perineal fistula as the most common malformation in male patients. Conclusion With the exception of perineal fistulas in females, the incidence of specific subtypes of ARMs was similar in the two groups. This may be of importance when extrapolating European study conclusion to the South African setting.