Correlation of PUV and SUV in the extremities while using PEM as a high-resolution positron emission scanner
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- 作者：Sania Rahim (1) (4)
Osama Mawlawi (1)
Patricia Fox (2)
Shree Taylor (1)
Richelle Millican (1)
Nancy M. Swanston (1)
J. Elliott Brown (3)
Eric M. Rohren (1) - 关键词：Positron emission mammography ; PEM ; High ; resolution positron emission scanner ; PUV ; Limb salvage imaging
- 刊名：Skeletal Radiology
- 出版年：2014
- 出版时间：April 2014
- 年：2014
- 卷：43
- 期：4
- 页码：453-458
- 全文大小：325 KB
- 作者单位：Sania Rahim (1) (4)
Osama Mawlawi (1)
Patricia Fox (2)
Shree Taylor (1)
Richelle Millican (1)
Nancy M. Swanston (1)
J. Elliott Brown (3)
Eric M. Rohren (1)
1. Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
4. MD Anderson Cancer Center, 1400 Pressler FCT 16.6007, Houston, TX, 77030, USA
2. Division of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
3. Department of Radiology, Yale University Hospital, New Haven, CT, USA - ISSN：1432-2161
文摘
Objective Owing to its unique configuration of two adjustable plate detectors positron emission mammography, or PEM, could theoretically also function as a high-resolution positron emission scanner for the extremities or neck. PEM quantitates its activity via a “PEM uptake value,-or PUV, and although its relationship to the standardized uptake value, or SUV, has been demonstrated in the breasts, to our knowledge there are no studies validating PUV in other sites such as the extremities. Materials and methods This was a retrospective chart review of two separate protocols of a total of 15 patients. The patients all had hypermetabolic lesions in the extremities or neck on imaging with PET/CT and were sent after their PET/CT to PEM for further imaging. Owing to the sequential nature of these examinations no additional radiotracer was administered. Results Spearman’s rank order correlation was calculated between the PUVmax obtained from PEM images, and the SUVmax for all. Spearman’s rank order correlation for all sites was 0.42, which is not significantly different from 0 (p--.13). When neck lesions were excluded from the group, there was a strong and statistically significant correlation between PUVmax and SUVmax, with Spearman’s rank correlation of 0.73, and significantly different from 0 (p--.0068). Discussion The correlation of PUV and SUV in the extremities indicates the potential use of PEM as a semiquantitative, high-resolution positron emission scanner and warrants further investigation, especially in the realms of disease processes that often present in the extremities, such as melanoma, osteomyelitis, and arthritis, as well as playing a role in the imaging of patients with metallic hardware post-limb salvage surgery.