Patient-specific finite element analysis of popliteal stenting
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- 作者：Michele Conti ; Michele Marconi ; Giulia Campanile ; Alessandro Reali…
- 关键词：Finite element analysis (FEA) ; Biomechanics ; Popliteal stenting ; Patient ; specific ; Nitinol
- 刊名：Meccanica
- 出版年：2017
- 出版时间：February 2017
- 年：2017
- 卷：52
- 期：3
- 页码：633-644
- 全文大小：
- 刊物类别：Physics and Astronomy
- 刊物主题：Classical Mechanics; Civil Engineering; Automotive Engineering; Mechanical Engineering;
- 出版者：Springer Netherlands
- ISSN：1572-9648
- 卷排序：52
文摘
Nitinol self-expanding stents are used for the endovascular management of peripheral artery diseases of the popliteal artery, which is located behind the knee joint. Unfortunately, the complex kinematics of the artery during the leg flexion leads to severe loading conditions, favouring the mechanical failure of the stent, calling for a specific biomechanical analysis. For this reason, in the present study we reconstruct by medical image analysis the patient-specific popliteal kinematics during leg flexion, which is subsequently exploited to compute the mechanical response of a stent model, virtually implanted in the artery by structural finite element analysis (FEA). The medical image analysis indicates a non-uniform configuration change of the artery during the leg flexion, leading to an increase of the vessel curvature above the knee. The computed mechanical response of the stent reflects the non-uniform configuration change of the artery as after the flexion the average stress is higher in the part of the stent located above the knee. Although the proposed analysis is limited to a case-study, it shows the capability of patient-specific FEA simulations to compute the mechanical response of a stent model subjected to the complex and severe loading conditions of the popliteal artery during leg flexion.