"In sickness and in health": the peculiar occurrence of polymyalgia rheumatica in married cohabiting couples—a case series and review of the literature
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  • 作者:Maria Chiara Gerardi ; Iolanda Maria Rutigliano ; Rossana Scrivo…
  • 关键词:Environmental factors ; Etiopathogenesis ; Giant ; cell arteritis ; Married couples ; Polymyalgia rheumatica
  • 刊名:Clinical Rheumatology
  • 出版年:2016
  • 出版时间:April 2016
  • 年:2016
  • 卷:35
  • 期:4
  • 页码:1111-1115
  • 全文大小:125 KB
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  • 作者单位:Maria Chiara Gerardi (1)
    Iolanda Maria Rutigliano (1)
    Rossana Scrivo (1)
    Roberta Priori (1)
    Valeria Riccieri (1)
    Guido Valesini (1)

    1. Dipartimento di Medicina Interna e Specialità Mediche, Reumatologia, Sapienza Università di Roma, Viale del Policlinico 155, 00161, Rome, Italy
  • 刊物类别:Medicine
  • 刊物主题:Medicine & Public Health
    Rheumatology
  • 出版者:Springer London
  • ISSN:1434-9949
文摘
Polymyalgia rheumatica (PMR) is an inflammatory rheumatic disorder in elderly people. It is frequently associated with giant-cell arteritis (GCA), although it is still debated if they are the same disease or two distinct pathologies. The etiology of PMR remains challenging, although current knowledge supports the role of both genetic and environmental factors. Among these, there is evidence that infectious agents could trigger the disease’s onset in some cases. We describe the peculiar case where PMR occurred in two Italian married and cohabiting couples and provide a review of the literature for similar cases. This is the first reported occurrence of PMR in two conjugal pairs in Italy. Moreover, in the second case, the wife presented PMR associated with GCA. To date, seven cases of PMR and two of GCA in married couples are described in the literature. The occurrence of PMR in both a husband and a wife supports the pathogenetic role of an environmental factor.

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