Treatment of High-Grade Dysplasia and Early Stage Esophageal Adenocarcinoma with an Endoscope: The Ultimate in Minimally Invasive, Curative Therapy
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- 作者：Wayne L. Hofstetter (1)
Marta L. Davila (2) - 关键词：Dysplasia ; Early stage esophageal adenocarcinoma ; Radiofrequency ablation ; Cryotherapy ; Endoscopic resection ; Esophagectomy ; Intramucosal cancer ; Endoscope ; Treatment
- 刊名：Current Surgery Reports
- 出版年：2014
- 出版时间：September 2014
- 年：2014
- 卷：2
- 期：9
- 全文大小：1,145 KB
- 参考文献：1. 鈥?Spechler SJ, Sharma P, Souza RF, et al. American Gastroenterological Association Medical Position Statement on the management of Barrett鈥檚 esophagus. Gastroenterol 2011;140:1084鈥?1
2. Sampliner RE. Practice guidelines on the diagnosis, surveillance and therapy of Barrett鈥檚 esophagus. Am J Gastroenterol. 1998;93:1028鈥?1. lass="external" href="http://dx.doi.org/10.1111/j.1572-0241.1998.00362.x" target="_blank" title="It opens in new window">CrossRef
3. Jung KW, Talley NJ, Romero Y, et al. Epidemiology and natural history of intestinal metaplasia of the gastroesophageal junction and Barrett鈥檚 esophagus: a population-based study. Am J Gastroenterol. 2011;106:1447鈥?5. lass="external" href="http://dx.doi.org/10.1038/ajg.2011.130" target="_blank" title="It opens in new window">CrossRef
4. Hvid-Jensen F, Pedersen L, Drewes AM, et al. Incidence of adenocarcinoma among patients with Barrett鈥檚 esophagus. N Engl J Med. 2011;365:1375鈥?3. lass="external" href="http://dx.doi.org/10.1056/NEJMoa1103042" target="_blank" title="It opens in new window">CrossRef
5. Hur C, Miller M, Kong CY, et al. Trends in esophageal adenocarcinoma incidence and mortality. Cancer. 2013;119:1149鈥?8. lass="external" href="http://dx.doi.org/10.1002/cncr.27834" target="_blank" title="It opens in new window">CrossRef
6. Yates M, Cheong E, Luben R, Igali L, Fitzgerald R, Khaw KT, Hart A. Body mass index, smoking, and alcohol and risks of Barrett鈥檚 esophagus and esophageal adenocarcinoma: a UK prospective cohort study. Dig Dis Sci. 2014.
7. Goldblum JR. Barrett鈥檚 esophagus and Barrett鈥檚-related dysplasia. Mod Pathol. 2003;16:316鈥?4. lass="external" href="http://dx.doi.org/10.1097/01.MP.0000062996.66432.12" target="_blank" title="It opens in new window">CrossRef
8. Malfertheiner P, Nocon M, Vieth M, Stolte M, Jaspersen D, Koelz HR, Labenz J, Leodolter A, Lind T, Richter K, Willich SN, Corley DA, Levin TR, Habel LA, et al. Evolution of gastro-oesophageal reflux disease over 5聽years under routine medical care鈥攖he ProGERD study. Aliment Pharmacol Ther. 2012;35(1):154鈥?4. lass="external" href="http://dx.doi.org/10.1111/j.1365-2036.2011.04901.x" target="_blank" title="It opens in new window">CrossRef
9. Corley DA, Levin HR, Habel LA, et al. Surveillance and survival in Barrett鈥檚 adenocarcinoma: a population based study. Gastroenterology. 2002;122:633鈥?0. lass="external" href="http://dx.doi.org/10.1053/gast.2002.31879" target="_blank" title="It opens in new window">CrossRef
10. Fountoulakis A, Zafirellis K, Donlan K, et al. Effect of surveillance of Barrett鈥檚 oesophagus on clinical outcome of oesophageal cancer. Br J Surg. 2004;91:997鈥?003. lass="external" href="http://dx.doi.org/10.1002/bjs.4591" target="_blank" title="It opens in new window">CrossRef
11. Evans JA, Early DS, Fukami N, et al. The role of endoscopy in Barrett鈥檚 esophagus and other premalignant conditions of the esophagus. Gastrointest Endosc. 2012;76:1087鈥?4. lass="external" href="http://dx.doi.org/10.1016/j.gie.2012.08.004" target="_blank" title="It opens in new window">CrossRef
12. Fernando HC, Murthy SC, Hofstetter W, et al. The Society of Thoracic Surgeons practice guideline series: guidelines for the management of Barrett鈥檚 esophagus with high-grade dysplasia. Ann Thorac Surg. 2009;87:1993鈥?002. lass="external" href="http://dx.doi.org/10.1016/j.athoracsur.2009.04.032" target="_blank" title="It opens in new window">CrossRef
13. 鈥?Phoa KN, van Vilsteren FG, Weusten BL, Bisschops R, Schoon EJ, Ragunath K, Fullarton G, Di Pietro M, Ravi N, Visser M, Offerhaus GJ, Seldenrijk CA, Meijer SL, ten Kate FJ, Tijssen JG, Bergman JJ. Radiofrequency ablation vs endoscopic surveillance for patients with Barrett esophagus and low-grade dysplasia: a randomized clinical trial. JAMA. 2014;311(12):1209鈥?7.
14. 鈥?Bennett C, Vakil N, Bergman J, et al. Consensus statements for management of Barrett鈥檚 dysplasia and early stage esophageal adenocarcinoma, based on a Delphi process. Gastroenterology 2012;143:336鈥?6.
15. Rastogi A, Puli S, El-Serag HB, et al. Incidence of esophageal adenocarcinoma in patients with Barrett鈥檚 esophagus and high-grade dysplasia: a meta-analysis. Gastrointest Endosc. 2008;67:394鈥?. lass="external" href="http://dx.doi.org/10.1016/j.gie.2007.07.019" target="_blank" title="It opens in new window">CrossRef
16. 鈥⑩€?Shaheen NJ, Sharma P, Overholt BF, et al. Radiofrequency ablation in Barrett鈥檚 esophagus with dysplasia. N Engl J Med 2009;360:2277鈥?8.
17. Konda VJ, Ross AS, Ferguson MK, et al. Is the risk of concomitant invasive esophageal cancer in high-grade dysplasia in Barrett鈥檚 esophagus overestimated? Clin Gastroenterol Hepatol. 2008;6:159鈥?4. lass="external" href="http://dx.doi.org/10.1016/j.cgh.2007.09.013" target="_blank" title="It opens in new window">CrossRef
18. Gupta N, Gaddam S, Wani SB, et al. Longer inspection time is associated with increase detection of high-grade dysplasia and esophageal adenocarcinoma in Barrett鈥檚 esophagus. Gastrointest Endosc. 2012;76:531鈥?. lass="external" href="http://dx.doi.org/10.1016/j.gie.2012.04.470" target="_blank" title="It opens in new window">CrossRef
19. Panossian AM, Raimondo M, Wolfsen HC. State of the art in the endoscopic imaging and ablation of Barrett鈥檚 esophagus. Dig Liver Dis. 2011;43:365鈥?3. lass="external" href="http://dx.doi.org/10.1016/j.dld.2011.01.011" target="_blank" title="It opens in new window">CrossRef
20. Thosani N, Singh H, Kapadia A, Ochi N, Lee JH, Ajani J, Swisher SG, Hofstetter WL, Guha S, Bhutani MS. Diagnostic accuracy of EUS in differentiating mucosal versus submucosal invasion of superficial esophageal cancers: a systematic review and meta-analysis. Gastrointest Endosc. 2012;75(2):242鈥?3. lass="external" href="http://dx.doi.org/10.1016/j.gie.2011.09.016" target="_blank" title="It opens in new window">CrossRef
21. May A, G眉nter E, Roth F, et al. Accuracy of staging in early oesophageal cancer using high resolution endoscopy and high resolution endosonography: a comparative, prospective, and blinded trial. Gut. 2004;53:634鈥?0. lass="external" href="http://dx.doi.org/10.1136/gut.2003.029421" target="_blank" title="It opens in new window">CrossRef
22. 鈥?Young PE, Gentry AB, Acosta RD, et al. Endoscopic Ultrasound does not accurately stage early adenocarcinoma or high-grade dysplasia of the esophagus. Clin Gastroenterol Hepatol 2010;8:1037鈥?1.
23. Shami VM, Villaverde A, Stearns L, et al. Clinical impact of conventional endosonography and endoscopic ultrasound-guided fine needle aspiration in the assessment of patients with Barrett鈥檚 esophagus and high-grade dysplasia or intramucosal carcinoma who have been referred for endoscopic ablation therapy. Endoscopy. 2006;38:157鈥?1. lass="external" href="http://dx.doi.org/10.1055/s-2005-921075" target="_blank" title="It opens in new window">CrossRef
24. Moss A, Bourke MJ, Hourigan LF, et al. Endoscopic resection for Barrett鈥檚 high-grade dysplasia and early esophageal adenocarcinoma: an essential staging procedure with long-term therapeutic benefit. Am J Gastroenterol. 2010;105:1276鈥?3. lass="external" href="http://dx.doi.org/10.1038/ajg.2010.1" target="_blank" title="It opens in new window">CrossRef
25. Peters FP, Brakenhoff KP, Curvers WL, et al. Histologic evaluation of resection specimens obtained at 293 endoscopic resections in Barrett鈥檚 esophagus. Gastrointest Endosc. 2008;67:604鈥?. lass="external" href="http://dx.doi.org/10.1016/j.gie.2007.08.039" target="_blank" title="It opens in new window">CrossRef
26. Shaheen NJ, Overholt BF, Sampliner RE, et al. Durability of radiofrequency ablation in Barrett鈥檚 esophagus with dysplasia. Gastroenterol. 2011;141:460鈥?. lass="external" href="http://dx.doi.org/10.1053/j.gastro.2011.04.061" target="_blank" title="It opens in new window">CrossRef
27. Ganz RA, Overholt BF, Sharma VK, et al. Circumferential ablation of Barrett鈥檚 esophagus that contains high-grade dysplasia: a U.S. multicenter registry. Gastrointest Endosc. 2008;68:35鈥?0. lass="external" href="http://dx.doi.org/10.1016/j.gie.2007.12.015" target="_blank" title="It opens in new window">CrossRef
28. Fleischer DE, Overholt BF, Sharma VK, et al. Endoscopic radiofrequency ablation for Barrett鈥檚 esophagus: 5-year outcomes from a prospective multicenter trial. Endoscopy. 2010;42:781鈥?. lass="external" href="http://dx.doi.org/10.1055/s-0030-1255779" target="_blank" title="It opens in new window">CrossRef
29. Bulsiewicz WJ, Kim HP, Dellon ES, et al. Safety and efficacy of endoscopic mucosal therapy with radiofrequency ablation for patients with neoplastic Barrett鈥檚 esophagus. Clin Gastroenterol Hepatol. 2013;11:636鈥?2. lass="external" href="http://dx.doi.org/10.1016/j.cgh.2012.10.028" target="_blank" title="It opens in new window">CrossRef
30. Vaccaro BJ, Gonzalez S, Poneros JM, et al. Detection of intestinal metaplasia after successful eradication of Barrett鈥檚 esophagus with radiofrequency ablation. Dig Dis Sci. 2011;56:1996鈥?000. lass="external" href="http://dx.doi.org/10.1007/s10620-011-1680-4" target="_blank" title="It opens in new window">CrossRef
31. Orman ES, Kim HP, Bulsiewicz WJ, et al. Intestinal metaplasia recurs infrequently in patients successfully treated for Barrett鈥檚 esophagus with radiofrequency ablation. Am J Gastroenterol. 2012;108:187鈥?5. lass="external" href="http://dx.doi.org/10.1038/ajg.2012.413" target="_blank" title="It opens in new window">CrossRef
32. Titi M, Overhiser A, Ulusarac O, et al. Development of subsquamous high-grade dysplasia and adenocarcinoma after successful radiofrequency ablation of Barrett鈥檚 esophagus. Gastroenterology. 2012;143:564鈥?. lass="external" href="http://dx.doi.org/10.1053/j.gastro.2012.04.051" target="_blank" title="It opens in new window">CrossRef
33. Greenwald BD, Dumot JA. Cryotherapy for Barrett鈥檚 esophagus and esophageal cancer. Curr Opin Gastroenterol. 2011;27:363鈥?. lass="external" href="http://dx.doi.org/10.1097/MOG.0b013e328347bae8" target="_blank" title="It opens in new window">CrossRef
34. Shaheen NJ, Greenwald BD, Peery AF, et al. Safety and efficacy of endoscopic spray cryotherapy for Barrett鈥檚 esophagus with high-grade dysplasia. Gastrointest Endosc. 2010;71:680鈥?. lass="external" href="http://dx.doi.org/10.1016/j.gie.2010.01.018" target="_blank" title="It opens in new window">CrossRef
35. Greenwald BD, Dumot JA, Abrams JA, et al. Endoscopic spray cryotherapy for esophageal cancer: safety and efficacy. Gastrointest Endosc. 2010;71:686鈥?3. lass="external" href="http://dx.doi.org/10.1016/j.gie.2010.01.042" target="_blank" title="It opens in new window">CrossRef
36. 鈥?Pech O, Bollschweiler E, Manner H, Leers J, Ell C, Holscher AH. Comparison between endoscopic and surgical resection of mucosal esophageal adenocarcinoma in Barrett鈥檚 esophagus at two high-volume centers. Ann Surg. 2011;254(1):67鈥?2
37. Pech O, Behrens A, May A, et al. Long-term results and risk factor analysis for recurrence after curative endoscopic therapy in 349 patients with high-grade intraepithelial neoplasia and mucosal adenocarcinoma in Barrett鈥檚 oesophagus. Gut. 2008;57(9):1200鈥?. lass="external" href="http://dx.doi.org/10.1136/gut.2007.142539" target="_blank" title="It opens in new window">CrossRef
38. Manner H, Pech O, Heldmann Y, et al. Efficacy, safety, and long-term results of endoscopic treatment for early-stage adenocarcinoma of the esophagus with low-risk sm1 invasion. Clinical Gastroenterol Hepatol. 2013;11:630鈥?. lass="external" href="http://dx.doi.org/10.1016/j.cgh.2012.12.040" target="_blank" title="It opens in new window">CrossRef
39. 鈥?Lee L, Ronellenfitsch U, Hofstetter WL, Darling G, Gaiser T, Lippert C, Gilbert S, Seely AJ, Mulder DS, Ferri LE. Predicting lymph node metastases in early esophageal adenocarcinoma using a simple scoring system. J Am Coll Surg. 2013;217:191鈥?.
40. 鈥?Pouw RE, van Vilsteren FG, Peters FP, Herrero LA, Ten Kate FJ, Visser M, Schenk BE, Schoon EJ, Peters FT, Houben M, Bisschops R, Weusten BL, Bergman JJ. Randomized trial on endoscopic resection-cap versus multiband mucosectomy for piecemeal endoscopic resection of early Barrett鈥檚 neoplasia. Gastrointest Endosc. 2011;74(1):35鈥?3
41. Alvarez Herrero L, Pouw RE, van Vilsteren FG, ten Kate FJ, Visser M, van Berge Henegouwen MI, Weusten BL, Bergman JJ JJ. Risk of lymph node metastasis associated with deeper invasion by early adenocarcinoma of the esophagus and cardia: study based on endoscopic resection specimens. Endoscopy. 2010;42(12):1030鈥?. lass="external" href="http://dx.doi.org/10.1055/s-0030-1255858" target="_blank" title="It opens in new window">CrossRef
42. May A, Gossner L, Pech O. Local endoscopic therapy for intraepithelial high-grade neoplasia and early adenocarcinoma in Barrett鈥檚 esophagus: acute-phase and intermediate results of a new treatment approach. Eur J Gastroenterol Hepatol. 2002;14:1085鈥?1. lass="external" href="http://dx.doi.org/10.1097/00042737-200210000-00009" target="_blank" title="It opens in new window">CrossRef
43. Pouw RE, Wirths K, Eisendrath P, et al. Efficacy of Radiofrequency ablation combined with endoscopic resection for Barrett鈥檚 esophagus with early neoplasia. Clin Gastroenterol Hepatol. 2010;8:23鈥?. lass="external" href="http://dx.doi.org/10.1016/j.cgh.2009.07.003" target="_blank" title="It opens in new window">CrossRef
44. Kim HP, Bulsiewicz WJ, Cotton CC, et al. Focal endoscopic mucosal resection before radiofrequency ablation is equally effective and safe compared with radiofrequency ablation alone for the eradication of Barrett鈥檚 esophagus with advanced neoplasia. Gastrointest Endosc. 2012;76:733鈥?. lass="external" href="http://dx.doi.org/10.1016/j.gie.2012.04.459" target="_blank" title="It opens in new window">CrossRef
45. Van Vilsteren FG, Pouw RE, Seewald S, et al. Stepwise radical endoscopic resection versus radiofrequency ablation for Barrett鈥檚 oesophagus with high-grade dysplasia or early cancer: a multicenter randomized trial. Gut. 2011;60:765鈥?3. lass="external" href="http://dx.doi.org/10.1136/gut.2010.229310" target="_blank" title="It opens in new window">CrossRef
46. Zehetner J, DeMeester SR, Hagen JA, et al. Endoscopic resection and ablation versus esophagectomy for high-grade dysplasia and intramucosal adenocarcinoma. J Thor Cardiovasc Surg. 2011;141:39鈥?7. lass="external" href="http://dx.doi.org/10.1016/j.jtcvs.2010.08.058" target="_blank" title="It opens in new window">CrossRef - 作者单位：Wayne L. Hofstetter (1)
Marta L. Davila (2)
1. Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, 1400 Pressler Ave Unit 1489, Houston, TX, 77030, USA
2. Department of Gastroenterology, Hepatology and Nutrition, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 146, Houston, TX, 77030, USA - ISSN：2167-4817
文摘
There has been a radical paradigm shift away from esophagectomy as the standard of therapy for high-grade dysplasia and early esophageal cancer. A number of organ-sparing endoscopic procedures including endoscopic resection, radiofrequency ablation and cryoablation are emerging as viable and preferable options for the treatment of early esophageal neoplasia. This review article will discuss ideal candidates for endoscopic therapies, current treatment modalities, clinical and safety outcomes, and specific management recommendations.