Femoral Arterial Thrombosis After Cardiac Catheterization In Infancy: Impact of Doppler Ultrasound for Diagnosis

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• 作者：Walter Knirsch (1)
  Christian Kellenberger (2)
  Sven Dittrich (3)
  Peter Ewert (4)
  Martin Lewin (5)
  Reinald Motz (6)
  Jan Nürnberg (7)
  Oliver Kretschmar (1)
  
• 关键词：Pediatric catheter intervention ; Complication ; Arterial thrombosis
• 刊名：Pediatric Cardiology
• 出版年：2013
• 出版时间：March 2013
• 年：2013
• 卷：34
• 期：3
• 页码：530-535
• 全文大小：172KB
• 参考文献：1. Alioglu B, Avci Z, Tokel K, Atac FB, Ozbek N (2008) Thrombosis in children with cardiac pathology: analysis of acquired and inherited risk factors. Blood Coagul Fibrinolysis 19:294-04 CrossRef
  2. Andrew M, David M, Adams M, Ali K, Anderson R, Barnard D et al (1994) Venous thromboembolic complications (VTE) in children: first analyses of the Canadian Registry of VTE. Blood 83:1251-257
  3. Balaguru D, Dilawar M, Ruff P, Radtke WA (2003) Early and late results of thrombolytic therapy using tissue-type plasminogen activator to restore arterial pulse after cardiac catheterization in infants and small children. Am J Cardiol 91:908-10 CrossRef
  4. Bontadelli J, Moeller A, Schmugge M, Schraner T, Kretschmar O, Bauersfeld U et al (2007) Enoxaparin therapy for arterial thrombosis in infants with congenital heart disease. Intensive Care Med 33:1978-984 CrossRef
  5. Brotschi B, Hug MI, Latal B, Neuhaus D, Buerki C, Kroiss S et al (2011) Incidence and predictors of indwelling arterial catheter-related thrombosis in children. J Thromb Haemost 9:1157-162 CrossRef
  6. Bulbul ZR, Galal MO, Mahmoud E, Narden B, Solymar L, Chaudhary MA et al (2002) Arterial complications following cardiac catheterization in children less than 10?kg. Asian Cardiovasc Thorac Ann 10:129-32
  7. Cohn HE, Freed MD, Hellenbrand WF, Fyler DC (1985) Complications and mortality associated with cardiac catheterization in infants under one year: a prospective study. Pediatr Cardiol 6:123-31 CrossRef
  8. Fellows KE Jr (1984) Therapeutic catheter procedures in congenital heart disease: current status and future prospects. Cardiovasc Intervent Radiol 7:170-77 CrossRef
  9. King MA, Garrison MM, Vavilala MS, Zimmerman JJ, Rivara FP (2008) Complications associated with arterial catheterization in children. Pediatr Crit Care Med 9:367-71 CrossRef
  10. Monagle P, Newall F, Barnes C, Savoia H, Campbell J, Wallace T et al (2008) Arterial thromboembolic disease: a single-centre case series study. J Paediatr Child Health 44:28-2
  11. Mori Y, Nakazawa M, Yagihara T (2010) Complications of pediatric cardiac catheterization and system of catheterization laboratories minimizing complications—a Japanese multicenter survey. J Cardiol 56:183-88 CrossRef
  12. Mullins CE (ed) (2006) Complications of diagnostic and therapeutic cardiac catheterizations. Cardiac catheterization in congenital heart disease: pediatric and adult, 1st edn. Blackwell Publishing, MA
  13. Ozbek N, Alioglu B, Avci Z, Malbora B, Onay O, Ozyurek E et al (2009) Incidence of and risk factors for childhood thrombosis: a single-center experience in Ankara, Turkey. Pediatr Hematol Oncol 26:11-9 CrossRef
  14. Price VE, Chan AK (2008) Arterial thrombosis in children. Expert Rev Cardiovasc Ther 6:419-28 CrossRef
  15. Saxena A, Gupta R, Kumar RK, Kothari SS, Wasir HS (1997) Predictors of arterial thrombosis after diagnostic cardiac catheterization in infants and children randomized to two heparin dosages. Catheter Cardiovasc Diagn 41:400-03 CrossRef
  16. Sutton N, Lock JE, Geggel RL (2006) Cardiac catheterization in infants weighing less than 1,500 grams. Catheter Cardiovasc Interv 68:948-56 CrossRef
  17. Tuckuviene R, Kristensen SR, Helgestad J, Christensen AL, Johnsen SP (2010) Predictive value of pediatric thrombosis diagnoses in the Danish National Patient Registry. Clin Epidemiol 2:107-22
  18. van Ommen CH, Ottenkamp J, Lam J, Brennickmeier M, Heijmans HS, Buller HR et al (2002) The risk of postthrombotic syndrome in children with congenital heart disease. J Pediatr 141:582-86 CrossRef
  19. Vitiello R, McCrindle BW, Nykanen D, Freedom RM, Benson LN (1998) Complications associated with pediatric cardiac catheterization. J Am Coll Cardiol 32:1433-440 CrossRef
  20. Zeevi B, Berant M, Fogelman R, Galit BM, Blieden LC (1999) Acute complications in the current era of therapeutic cardiac catheterization for congenital heart disease. Cardiol Young 9:266-72
  
• 作者单位：Walter Knirsch (1)
  Christian Kellenberger (2)
  Sven Dittrich (3)
  Peter Ewert (4)
  Martin Lewin (5)
  Reinald Motz (6)
  Jan Nürnberg (7)
  Oliver Kretschmar (1)
  
  1. Division of Pediatric Cardiology, University Children’s Hospital, Steinwiesstrasse 75, 8032, Zurich, Switzerland
  2. Division of Diagnostic Imaging, University Children’s Hospital, 8032, Zurich, Switzerland
  3. Department of Pediatric Cardiology, University Hospital, 91052, Erlangen, Germany
  4. Department of Congenital Heart Disease and Pediatric Cardiology, German Heart Institute Berlin, 13353, Berlin, Germany
  5. Department of Pediatric Cardiology and Intensive Care Medicine, Klinikum Stuttgart Olgahospital, 70176, Stuttgart, Germany
  6. Pediatric Cardiology, Klinikum Oldenburg, 26133, Oldenburg, Germany
  7. Department of Congenital Heart Disease/Pediatric Cardiology, Klinikum Links der Weser, 28277, Bremen, Germany
  
• ISSN：1432-1971

文摘

Femoral arterial thrombosis (FAT) is a nonnegligible complication after cardiac catheterization (CC) in infancy. The aim of this study was to evaluate the impact of Doppler ultrasound (US) for diagnostic work-up after catheterization. We compared standard follow-up (FU) without Doppler US by relying on clinical signs of FAT with advanced FU using Doppler US of the femoral vessels. Between January and December 2009, we evaluated the rate of FAT in infants <12?months of age using a multicenter, prospective observational survey. We analysed 171 patients [mean age 4.1?±?3.3 (SD) months; mean body weight 5.3?±?1.8?kg] from 6 participating centres. The mean duration of catheter studies was 57.7?±?38.0?min. The overall rate of FAT based on clinical diagnosis was 4.7?% and was comparable in both groups [3.4?% undergoing standard FU vs. 7.4?% undergoing advanced FU (p?=?0.15)]. However, the overall rate of thrombosis as screened by Doppler US was greater at 7.1?%, especially in patients after advanced FU [18.5?% advanced vs. standard FU 1.7?% (p?<?0.01)]. In conclusion, FAT remains a relevant and underestimated complication after catheterization in young infants when relying only on clinical signs of FAT. Therefore, to start effective treatment as soon as possible, we recommend Doppler US to be performed the day after CC.