文摘
We have revised a part of the diagnostic criteria for fulminant type 1 diabetes. The new criteria were set both to express the essence of this disease of rapid increase of patients-blood glucose and to be highly sensitive to reduce the misdiagnosis. After analyzing the data of 382 patients with newly-diagnosed fulminant type 1 diabetes, we adopted the HbA1c level of 8.7?% (NGSP value). The new criterion indicates 100?% of sensitivity and best value by ROC (receiver operation curve) analysis. In addition, we added a comment that “This value (HbA1c?<?8.7?% in NGSP) is not applicable for patients with previously diagnosed glucose intolerance-on the new criteria and also a comment that “Association with HLA DRB1*04:05-DQB1*04:01 is reported-as a related finding. We did not revise the screening criteria and the other part of the diagnostic criteria, because they are still reliable.