Reconstruction of the treatment area by use of sinogram in helical tomotherapy
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  • 作者:Akihiro Haga (1)
    Keiichi Nakagawa (1)
    Calvin Maurer (2)
    Ken Ruchala (2)
    Edward Chao (2)
    Dylan Casey (2)
    Satoshi Kida (1)
    Dousatsu Sakata (1)
    Masahiro Nakano (1)
    Taiki Magome (1)
    Yoshitaka Masutani (1)

    1. Department of Radiology
    ; University of Tokyo Hospital ; 7-3-1 Hongo ; Bunkyo ; Tokyo ; Japan
    2. Accuray Incorporated
    ; Sunnyvale ; CA ; USA
  • 关键词:Megavoltage CT ; In ; treatment CT ; Image reconstruction during treatment ; TomoTherapy庐
  • 刊名:Radiation Oncology
  • 出版年:2014
  • 出版时间:December 2014
  • 年:2014
  • 卷:9
  • 期:1
  • 全文大小:543 KB
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  • 刊物主题:Oncology; Radiotherapy;
  • 出版者:BioMed Central
  • ISSN:1748-717X
文摘
Background TomoTherapy (Accuray, USA) has an image-guided radiotherapy system with a megavoltage (MV) X-ray source and an on-board imaging device. This system allows one to acquire the delivery sinogram during the actual treatment, which partly includes information from the irradiated object. In this study, we try to develop image reconstruction during treatment with helical tomotherapy. Findings Sinogram data were acquired during helical tomotherapy delivery using an arc-shaped detector array that consists of 576 xenon-gas filled detector cells. In preprocessing, these were normalized with full air-scan data. A software program was developed that reconstructs 3D images during treatment with corrections as; (1) the regions outside the field were masked not to be added in the backprojection (a masking correction), and (2) each voxel of the reconstructed image was divided by the number of the beamlets passing through its voxel (a ray-passing correction). The masking correction produced a reconstructed image, however, it contained streak artifacts. The ray-passing correction reduced this artifact. Although the SNR (the ratio of mean to standard deviation in a homogeneous region) and the contrast of the reconstructed image were slightly improved with the ray-passing correction, use of only the masking correction was sufficient for the visualization purpose. Conclusions The visualization of the treatment area was feasible by using the sinogram in helical tomotherapy. This proposed method would be useful in the treatment verification.

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