Critical review of SPECT imaging in pulmonary embolism
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- 作者：Paul D. Stein (1) (3)
H. Dirk Sostman (2)
Fadi Matta (1) - 关键词：Pulmonary embolism ; Venous thromboembolism ; Single ; photon emission computed tomography
- 刊名：Clinical and Translational Imaging
- 出版年：2014
- 出版时间：October 2014
- 年：2014
- 卷：2
- 期：5
- 页码：379-390
- 全文大小：228 KB
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H. Dirk Sostman (2)
Fadi Matta (1)
1. Department of Osteopathic Medical Specialties, Michigan State University College of Osteopathic Medicine, East Lansing, MI, USA
3. Michigan State University College of Osteopathic Medicine, 4707 St Antoine, Box 402, Detroit, MI, 48201, USA
2. Department of Radiology, Weill Cornell Medical College, New York, NY, USA - ISSN：2281-7565
文摘
Outcome studies have shown that pulmonary embolism can be safely excluded in patients with negative ventilation/perfusion (V/Q) single-photon emission computed tomography (SPECT). The effective radiation dose of V/Q SPECT is much less than with computed tomographic (CT) pulmonary angiography, which would make it preferable to CT angiography in many young female patients. The accuracy of V/Q SPECT, however, is difficult to assess, because most published investigations are limited by incorporation bias or partial verification bias, as well as other limitations in study design and reporting. Consequently, the accuracy of V/Q SPECT relative to planar V/Q scintigraphy or CT angiography has not been definitively determined. There is need for a prospective investigation of the accuracy of V/Q SPECT with consecutive patients, blinded interpretations, and an independent reference standard, or independent composite reference standard.