Lack of Evidence to Guide Deprescribing of Antihyperglycemics: A Systematic Review

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• 作者：Cody D. Black ; Wade Thompson ; Vivian Welch ; Lisa McCarthy&#8230
• 关键词：Antihyperglycemics ; Deprescribing ; Elderly ; Type 2 Diabetes
• 刊名：Diabetes Therapy
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：8
• 期：1
• 页码：23-31
• 全文大小：494KB
• 刊物主题：Internal Medicine; Diabetes; Cardiology; Endocrinology;
• 出版者：Springer Healthcare
• ISSN：1869-6961
• 卷排序：8

文摘

IntroductionIndividualizing glycemic targets to goals of care and time to benefit in persons with type 2 diabetes is good practice, particularly in populations at risk of hypoglycemia and adverse outcomes relating to the use of antihyperglycemics. Guidelines acknowledge the need for relaxed targets in frail older adults, but there is little guidance on how to safely deprescribe (i.e. stop, reduce or substitute) antihyperglycemics.