The genus Casearia: a phytochemical and pharmacological overview

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• 作者：Li Xia (1) (2)
  Qiang Guo (1)
  Pengfei Tu (1)
  Xingyun Chai (1)
  
  1. Modern Research Center for Traditional Chinese Medicine ; Beijing University of Chinese Medicine ; Beijing ; 100029 ; China
  2. School of Traditional Chinese Medicine ; Guangdong Food and Drug Vocational College ; Guangzhou ; 510520 ; China
  
• 关键词：Casearia ; Salicaceae sensu lato ; Flacourtiaceae ; Clerodane diterpenoid ; Cytotoxicity ; Hypoglycemic ; Anti ; snake venom ; Chemotaxonomy
• 刊名：Phytochemistry Reviews
• 出版年：2015
• 出版时间：February 2015
• 年：2015
• 卷：14
• 期：1
• 页码：99-135
• 全文大小：1,573 KB
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• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Life Sciences
  Plant Sciences
  Biochemistry
  Organic Chemistry
  Chemistry
  
• 出版者：Springer Netherlands
• ISSN：1572-980X

文摘

Casearia (Salicaceae sensu lato) species have been used as folk medicines in South American and Asian countries since ancient times. Previous phytochemical screenings demonstrated that the Casearia plants mainly contain clerodane diterpenoids, sesquiterpenoids, phenylpropanoids and other constituents from different chemical classes. The pharmacological studies confirmed that the crude extracts or individual compounds from the genus showed cytotoxic, hypoglycemic, antiulcer, and anti-inflammatory activities, as well as anti-snake venom property. In this review we presented a summary of the secondary metabolites isolated from Casearia species based on the published literatures through May 2013. In addition to the traditional medicinal use of Casearia plants and their taxonomic characteristics, we focused on the known biological activities of the plants and discussed them in detail here.