An analysis of unused and expired medications in Mexican households
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- 作者：Sandra Leticia Gracia-Vásquez…
- 关键词：Expired medications ; Medicine waste ; Mexico ; Therapeutic groups ; Unused medications
- 刊名：Pharmacy World Science
- 出版年：2015
- 出版时间：February 2015
- 年：2015
- 卷：37
- 期：1
- 页码：121-126
- 全文大小：467 KB
- 参考文献：1. Ruhoy IS, Daughton CG. Beyond the medicine cabinet: an analysis of where and why medications accumulate. Environ Int. 2008;34:1157-9. CrossRef
2. Corcoran J, Winter MJ, Tyler CR. Pharmaceuticals in the aquatic environment: a critical review of the evidence for health effects in fish. Crit Rev Toxicol. 2010;40(4):287-04. CrossRef
3. Consejo Nacional de Población. Datos de proyecciones (2013). http://www.conapo.gob.mx/es/CONAPO/Proyecciones_Datos. Accessed May 2014.
4. Instituto Nacional de Estadística Geografía e Informática. México en cifras (2012). http://www3.inegi.org.mx/sistemas/mexicocifras/. Accessed May 2014
5. Kusturica MP, Sabo A, Tomic Z, Horvat O, Solak Z. Storage and disposal of unused medications: knowledge, behavior, and attitudes among Serbian people. Int J Clin Pharm. 2012;34:604-0. CrossRef
6. Annear B, Sinclair K. Response to ‘returned medicines: waste or a wasted opportunity?- J Public Health. 2008;30(2):209-0. CrossRef
7. Guirguis K. Medications collected for disposal by outreach pharmacists in Australia. Pharm World Sci. 2010;32:52-. CrossRef
8. Runnalls TJ, Margiotta-Casaluci L, Kugathas S, Sumpter P. Pharmaceuticals in the aquatic environment: steroids and anti-steroids as high priorities for research. Hum Ecol Risk Assess. 2010;16:1318-8. CrossRef
9. Bound JP, Voulvoulis N. Household disposal of pharmaceuticals as a pathway for aquatic contamination in the United Kingdom. Environ Health Perspect. 2005;113:1705-1. CrossRef
10. Braund R, Peake BM, Shieffelbien L. Disposal practices for unused medications in New Zealand. Environ Int. 2009;35:952-. CrossRef
11. Prescott JD, Estler K. Waste not want not: drug disposal and the role of the pharmacist. Pharm Times. 2010;76:107-13.
12. Ríos L. Medicamentos caducos, riesgo para la salud [Internet]. México DF: Luis Quiroga; 03 Sep 2013 [Updated 15 Dec 2013; cited 27 Jan 2014]. http://www.vertigopolitico.com/articulo/21946/Medicamentos-caducos-riesgo-para-la-salud.
13. Tong AYC, Peake BM, Braund R. Disposal practices for unused medications around the world. Environ Int. 2011;37:292-. CrossRef
14. Butler CC, Rollnick S, Pill R, Maggs-Rapport F, Stott N. Understanding the culture of prescribing: qualitative study of general practitioners-and patients-perceptions of antibiotics for sore throats. BMJ. 1998;317:637-2. CrossRef
15. Sorensen L, Stokes JA, Purdie DM, Woodward M, Roberts MS. Medication management at home: medication-related risk factors associated with poor health outcomes. Age Ageing. 2005;34:626-2.
16. Jassim AM. In-home drug storage and self-medication with antimicrobial drugs in Basrah, Iraq. Oman Med J. 2010;25(2):79-7.
17. Daughton CG, Ruhoy IS. Green pharmacy and pharmEcovigilance: prescribing and the planet. Expert Rev Clin Pharmacol. 2011;4(2):211-2. CrossRef
18. Garey KW, Johle ML, Behrman K, Neuhauser MM. Economic consequences of unused medications in Houston, Texas. Ann Pharmacother. 2004;38:1165-168.
19. Ley General de Salud, México, Editorial SISTA, S.A. de C.V., 2008.
20. Wieczorkiewicz SM, Kassamali Z, Danziger LH. Behind closed doors: medication storage and disposal in the home. Ann Pharmacother. 2013;47:82-89.
文摘
Background Unsafe storage of unused medications at home leads to an increased risk of toxicity, accidental childhood poisoning or risk for suicide, whereas an improper disposal of unwanted/expired medications from household raises concern about environmental pollution. Objective The aim of the study was to characterize expired medications collected according to the types of therapeutic groups, pharmaceutical dosage forms, expiration dates and were prescribed or over the counter drugs, and whether they came from Mexican health system or purchased by patients themselves. Setting The study was conducted in the metropolitan area of Monterrey during a 12-month period from March 2012 to February 2013. Method Unused/expired drugs were collected according to the collection and disposal of expired medication program instituted by the Department of Health of the State of Nuevo León. Pharmacists and students from The Autonomous University of Nuevo León recorded types of therapeutic groups, total of medicines in each group, among other classification criteria. Main outcome measure The proportion of every collected therapeutic group, type of dosage forms, and expiration date. Results The amount of medications classified was 22,140 items corresponding to a 30?% of the total collected medications in that period of time; most of them belonged to the non-steroidal anti-inflammatory drugs (16.11?%). According to the pharmaceutical dosage forms, results showed that a high percentage were solid dosage forms (73.39?%), of the total unused/expired medications, most of them were prescription drugs (91?%) which were purchased at private pharmacies. Expiration date of medications ranges from 1995 to 2016, being 2011 the outstanding year (36.66?%). Conclusion Addressing the aspect of unused drug disposition constitutes a challenge for Mexican government, due to health implications related to inadequate disposition. No matter how efficient the programs of collection and disposal of expired drugs are, none of them can collect all unused or expired drugs, that is the reason why the best approach might be to prevent this need.