Bisphenol a exposure in Mexico City and risk of prematurity: a pilot nested case control study

详细信息    查看全文

• 作者：David Cantonwine (1)
  John D Meeker (1)
  Howard Hu (1) (2) (3)
  Brisa N Sánchez (4)
  Héctor Lamadrid-Figueroa (5)
  Adriana Mercado-García (6)
  Gamola Z Fortenberry (1)
  Antonia M Calafat (7)
  Martha Maria Téllez-Rojo (5)
  
• 刊名：Environmental Health
• 出版年：2010
• 出版时间：December 2010
• 年：2010
• 卷：9
• 期：1
• 全文大小：312KB
• 参考文献：1. Kang JH, Kito K, Kondo F: Factors influencing the migration of bisphenol A from cans. / J Food Prot 2003, 66:1444-447.
  2. Factor A: Mechanisms of thermal and photodegredations of bisphenol A polycarbonate. In / Polymer Durability, Degradation, Stabilization, and Lifetime Prediction. Edited by: Clough R, Billingham N, Gillen K. New York: Oxford University Press; 1998:59-6.
  3. Brede C, Fjeldal P, Skjevrak I, Herikstad H: Increased migration levels of bisphenol A from polycarbonate baby bottles after dishwashing, boiling and brushing. / Food Addit Contam 2003, 20:684-89. dx.doi.org/10.1080/0265203031000119061">CrossRef
  4. Vandenberg LN, Hauser R, Marcus M, Olea N, Welshons WV: Human exposure to bisphenol A (BPA). / Reprod Toxicol 2007, 24:139-77. dx.doi.org/10.1016/j.reprotox.2007.07.010">CrossRef
  5. Kang JH, Kondo F, Katayama Y: Human exposure to bisphenol A. / Toxicology 2006, 226:79-9. dx.doi.org/10.1016/j.tox.2006.06.009">CrossRef
  6. Calafat AM, Ye X, Wong LY, Reidy JA, Needham LL: Exposure of the U.S. population to bisphenol A and 4-tertiary-octylphenol: 2003-004. / Environ Health Perspect 2008, 116:39-4. dx.doi.org/10.1289/ehp.10753">CrossRef
  7. Ye X, Pierik FH, Hauser R, Duty S, Angerer J, Park MM, Burdorf A, Hofman A, Jaddoe VW, Mackenbach JP, / et al.: Urinary metabolite concentrations of organophosphorous pesticides, bisphenol A, and phthalates among pregnant women in Rotterdam, the Netherlands: the Generation R study. / Environ Res 2008, 108:260-67. dx.doi.org/10.1016/j.envres.2008.07.014">CrossRef
  8. Becker K, Goen T, Seiwert M, Conrad A, Pick-Fuss H, Muller J, Wittassek M, Schulz C, Kolossa-Gehring M: GerES IV: phthalate metabolites and bisphenol A in urine of German children. / Int J Hyg Environ Health 2009, 212:685-92. dx.doi.org/10.1016/j.ijheh.2009.08.002">CrossRef
  9. He Y, Miao M, Herrinton LJ, Wu C, Yuan W, Zhou Z, Li DK: Bisphenol A levels in blood and urine in a Chinese population and the personal factors affecting the levels. / Environ Res 2009, 109:629-33. dx.doi.org/10.1016/j.envres.2009.04.003">CrossRef
  10. Yamano Y, Miyakawa S, Iizumi K, Itoh H, Iwasaki M, Tsugane S, Kagawa J, Nakadate T: Long-term study of urinary bisphenol A in elementary school children. / Environ Health Prev Med 2008, 13:332-37. dx.doi.org/10.1007/s12199-008-0049-6">CrossRef
  11. Ye X, Pierik FH, Angerer J, Meltzer HM, Jaddoe VW, Tiemeier H, Hoppin JA, Longnecker MP: Levels of metabolites of organophosphate pesticides, phthalates, and bisphenol A in pooled urine specimens from pregnant women participating in the Norwegian Mother and Child Cohort Study (MoBa). / Int J Hyg Environ Health 2009, 212:481-91. dx.doi.org/10.1016/j.ijheh.2009.03.004">CrossRef
  12. Ikezuki Y, Tsutsumi O, Takai Y, Kamei Y, Taketani Y: Determination of bisphenol A concentrations in human biological fluids reveals significant early prenatal exposure. / Hum Reprod 2002, 17:2839-841. dx.doi.org/10.1093/humrep/17.11.2839">CrossRef
  13. Schonfelder G, Wittfoht W, Hopp H, Talsness CE, Paul M, Chahoud I: Parent bisphenol A accumulation in the human maternal-fetal-placental unit. / Environ Health Perspect 2002, 110:A703-07. dx.doi.org/10.1289/ehp.021100703">CrossRef
  14. Sun Y, Irie M, Kishikawa N, Wada M, Kuroda N, Nakashima K: Determination of bisphenol A in human breast milk by HPLC with column-switching and fluorescence detection. / Biomed Chromatogr 2004, 18:501-07. dx.doi.org/10.1002/bmc.345">CrossRef
  15. Richter CA, Birnbaum LS, Farabollini F, Newbold RR, Rubin BS, Talsness CE, Vandenbergh JG, Walser-Kuntz DR, vom Saal FS: In vivo effects of bisphenol A in laboratory rodent studies. / Reprod Toxicol 2007, 24:199-24. dx.doi.org/10.1016/j.reprotox.2007.06.004">CrossRef
  16. Wetherill YB, Akingbemi BT, Kanno J, McLachlan JA, Nadal A, Sonnenschein C, Watson CS, Zoeller RT, Belcher SM: In vitro molecular mechanisms of bisphenol A action. / Reprod Toxicol 2007, 24:178-98. dx.doi.org/10.1016/j.reprotox.2007.05.010">CrossRef
  17. Morck TJ, Sorda G, Bechi N, Rasmussen BS, Nielsen JB, Ietta F, Rytting E, Mathiesen L, Paulesu L, Knudsen LE: Placental transport and in vitro effects of Bisphenol A. / Reprod Toxicol 2010, 30:131-37. dx.doi.org/10.1016/j.reprotox.2010.02.007">CrossRef
  18. Benachour N, Aris A: Toxic effects of low doses of Bisphenol-A on human placental cells. / Toxicol Appl Pharmacol 2009, 241:322-28. dx.doi.org/10.1016/j.taap.2009.09.005">CrossRef
  19. Savabieasfahani M, Kannan K, Astapova O, Evans NP, Padmanabhan V: Developmental programming: differential effects of prenatal exposure to bisphenol-A or methoxychlor on reproductive function. / Endocrinology 2006, 147:5956-966. dx.doi.org/10.1210/en.2006-0805">CrossRef
  20. Padmanabhan V, Siefert K, Ransom S, Johnson T, Pinkerton J, Anderson L, Tao L, Kannan K: Maternal bisphenol-A levels at delivery: a looming problem? / J Perinatol 2008, 28:258-63. dx.doi.org/10.1038/sj.jp.7211913">CrossRef
  21. Wolff MS, Engel SM, Berkowitz GS, Ye X, Silva MJ, Zhu C, Wetmur J, Calafat AM: Prenatal phenol and phthalate exposures and birth outcomes. / Environ Health Perspect 2008, 116:1092-097. dx.doi.org/10.1289/ehp.11007">CrossRef
  22. Ettinger AS, Lamadrid-Figueroa H, Tellez-Rojo MM, Mercado-Garcia A, Peterson KE, Schwartz J, Hu H, Hernandez-Avila M: Effect of calcium supplementation on blood lead levels in pregnancy: a randomized placebo-controlled trial. / Environ Health Perspect 2009, 117:26-1. dx.doi.org/10.1289/ehp0800533">CrossRef
  23. Rosner B: Percentage Points for a Generalized ESD Many-Outlier Procedure. / Technometrics 1983, 25:165-72. dx.doi.org/10.2307/1268549">CrossRef
  24. Meeker JD, Hu H, Cantonwine DE, Lamadrid-Figueroa H, Calafat AM, Ettinger AS, Hernandez-Avila M, Loch-Caruso R, Tellez-Rojo MM: Urinary phthalate metabolites in relation to preterm birth in Mexico city. / Environ Health Perspect 2009, 117:1587-592.
  25. Braun JM, Yolton K, Dietrich KN, Hornung R, Ye X, Calafat AM, Lanphear BP: Prenatal bisphenol A exposure and early childhood behavior. / Environ Health Perspect 2009, 117:1945-952.
  26. Sugiura-Ogasawara M, Ozaki Y, Sonta S, Makino T, Suzumori K: Exposure to bisphenol A is associated with recurrent miscarriage. / Hum Reprod 2005, 20:2325-329. dx.doi.org/10.1093/humrep/deh888">CrossRef
  27. Yang M, Kim SY, Chang SS, Lee IS, Kawamoto T: Urinary concentrations of bisphenol A in relation to biomarkers of sensitivity and effect and endocrine-related health effects. / Environ Mol Mutagen 2006, 47:571-78. dx.doi.org/10.1002/em.20230">CrossRef
  28. Yamada H, Furuta I, Kato EH, Kataoka S, Usuki Y, Kobashi G, Sata F, Kishi R, Fujimoto S: Maternal serum and amniotic fluid bisphenol A concentrations in the early second trimester. / Reprod Toxicol 2002, 16:735-39. dx.doi.org/10.1016/S0890-6238(02)00051-5">CrossRef
  29. Goldenberg RL, Culhane JF, Iams JD, Romero R: Epidemiology and causes of preterm birth. / Lancet 2008, 371:75-4. dx.doi.org/10.1016/S0140-6736(08)60074-4">CrossRef
  30. Nakamura D, Yanagiba Y, Duan Z, Ito Y, Okamura A, Asaeda N, Tagawa Y, Li C, Taya K, Zhang SY, / et al.: Bisphenol A may cause testosterone reduction by adversely affecting both testis and pituitary systems similar to estradiol. / Toxicol Lett 194:16-5.
  31. Padmanabhan V, Sarma HN, Savabieasfahani M, Steckler TL, Veiga-Lopez A: Developmental reprogramming of reproductive and metabolic dysfunction in sheep: native steroids vs. environmental steroid receptor modulators. / Int J Androl 2010, 33:394-04. dx.doi.org/10.1111/j.1365-2605.2009.01024.x">CrossRef
  32. Rashid H, Ahmad F, Rahman S, Ansari RA, Bhatia K, Kaur M, Islam F, Raisuddin S: Iron deficiency augments bisphenol A-induced oxidative stress in rats. / Toxicology 2009, 256:7-2. dx.doi.org/10.1016/j.tox.2008.10.022">CrossRef
  33. Tayama S, Nakagawa Y, Tayama K: Genotoxic effects of environmental estrogen-like compounds in CHO-K1 cells. / Mutat Res 2008, 649:114-25.
  34. Tsutsui T, Tamura Y, Yagi E, Hasegawa K, Takahashi M, Maizumi N, Yamaguchi F, Barrett JC: Bisphenol-A induces cellular transformation, aneuploidy and DNA adduct formation in cultured Syrian hamster embryo cells. / Int J Cancer 1998, 75:290-94. dx.doi.org/10.1002/(SICI)1097-0215(19980119)75:2<290::AID-IJC19>3.0.CO;2-H">CrossRef
  35. Atkinson A, Roy D: In vivo DNA adduct formation by bisphenol A. / Environ Mol Mutagen 1995, 26:60-6. dx.doi.org/10.1002/em.2850260109">CrossRef
  36. Kabuto H, Hasuike S, Minagawa N, Shishibori T: Effects of bisphenol A on the metabolisms of active oxygen species in mouse tissues. / Environ Res 2003, 93:31-5. dx.doi.org/10.1016/S0013-9351(03)00062-8">CrossRef
  37. Cho SH, Choi MH, Kwon OS, Lee WY, Chung BC: Metabolic significance of bisphenol A-induced oxidative stress in rat urine measured by liquid chromatography-mass spectrometry. / J Appl Toxicol 2009, 29:110-17. dx.doi.org/10.1002/jat.1387">CrossRef
  38. Kabuto H, Amakawa M, Shishibori T: Exposure to bisphenol A during embryonic/fetal life and infancy increases oxidative injury and causes underdevelopment of the brain and testis in mice. / Life Sci 2004, 74:2931-940. dx.doi.org/10.1016/j.lfs.2003.07.060">CrossRef
  39. Chitra KC, Latchoumycandane C, Mathur PP: Induction of oxidative stress by bisphenol A in the epididymal sperm of rats. / Toxicology 2003, 185:119-27. dx.doi.org/10.1016/S0300-483X(02)00597-8">CrossRef
  40. Bindhumol V, Chitra KC, Mathur PP: Bisphenol A induces reactive oxygen species generation in the liver of male rats. / Toxicology 2003, 188:117-24.
  41. Dominguez MA, Petre MA, Neal MS, Foster WG: Bisphenol A concentration-dependently increases human granulosa-lutein cell matrix metalloproteinase-9 (MMP-9) enzyme output. / Reprod Toxicol 2008, 25:420-25. dx.doi.org/10.1016/j.reprotox.2008.05.059">CrossRef
  42. Xu J, Osuga Y, Yano T, Morita Y, Tang X, Fujiwara T, Takai Y, Matsumi H, Koga K, Taketani Y, / et al.: Bisphenol A induces apoptosis and G2-to-M arrest of ovarian granulosa cells. / Biochem Biophys Res Commun 2002, 292:456-62. dx.doi.org/10.1006/bbrc.2002.6644">CrossRef
  43. Kato I, Toniolo P, Koenig KL, Shore RE, Zeleniuch-Jacquotte A, Akhmedkhanov A, Riboli E: Epidemiologic correlates with menstrual cycle length in middle aged women. / Eur J Epidemiol 1999, 15:809-14. dx.doi.org/10.1023/A:1007669430686">CrossRef
  44. Munster K, Schmidt L, Helm P: Length and variation in the menstrual cycle--a cross-sectional study from a Danish county. / Br J Obstet Gynaecol 1992, 99:422-29. dx.doi.org/10.1111/j.1471-0528.1992.tb13762.x">CrossRef
  45. Rowland AS, Baird DD, Long S, Wegienka G, Harlow SD, Alavanja M, Sandler DP: Influence of medical conditions and lifestyle factors on the menstrual cycle. / Epidemiology 2002, 13:668-74. dx.doi.org/10.1097/00001648-200211000-00011">CrossRef
  46. Liu Y, Gold EB, Lasley BL, Johnson WO: Factors affecting menstrual cycle characteristics. / Am J Epidemiol 2004, 160:131-40. dx.doi.org/10.1093/aje/kwh188">CrossRef
  47. Mahalingaiah S, Meeker JD, Pearson KR, Calafat AM, Ye X, Petrozza J, Hauser R: Temporal variability and predictors of urinary bisphenol A concentrations in men and women. / Environ Health Perspect 2008, 116:173-78. dx.doi.org/10.1289/ehp.10605">CrossRef
  
• 作者单位：David Cantonwine (1)
  John D Meeker (1)
  Howard Hu (1) (2) (3)
  Brisa N Sánchez (4)
  Héctor Lamadrid-Figueroa (5)
  Adriana Mercado-García (6)
  Gamola Z Fortenberry (1)
  Antonia M Calafat (7)
  Martha Maria Téllez-Rojo (5)
  
  1. Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, Michigan, USA
  2. Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA
  3. Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA
  4. Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA
  5. Division of Statistics, Center for Evaluation Research and Surveys, National Institute of Public Health, Mexico, Cuernavaca, Morelos, México
  6. Division of Environmental Health, Center for Population Health Research, National Institute of Public Health, Cuernavaca, Morelos, México
  7. Centers for Disease and Control and Prevention, Atlanta, GA, USA
  

文摘

Background Presence of Bisphenol A (BPA) has been documented worldwide in a variety of human biological samples. There is growing evidence that low level BPA exposure may impact placental tissue development and thyroid function in humans. The aim of this present pilot study was to determine urinary concentrations of BPA during the last trimester of pregnancy among a small subset of women in Mexico City, Mexico and relate these concentrations to risk of delivering prematurely. Methods A nested case-control subset of 60 participants in the Early Life Exposure in Mexico to ENvironmental Toxicants (ELEMENT) study in Mexico City, Mexico were selected based on delivering less than or equal to 37 weeks of gestation and greater than 37 weeks of gestation. Third trimester archived spot urine samples were analyzed by online solid phase extraction coupled with high performance liquid chromatography isotope dilution tandem mass spectrometry. Results BPA was detected in 80.0% (N = 48) of the urine samples; total concentrations ranged from < 0.4 μg/L to 6.7 μg/L; uncorrected geometric mean was 1.52 μg/L. The adjusted odds ratio of delivering less than or equal to 37 weeks in relation to specific gravity adjusted third trimester BPA concentration was 1.91 (95%CI 0.93, 3.91, p-value = 0.08). When cases were further restricted to births occurring prior to the 37th week (n = 12), the odds ratio for specific-gravity adjusted BPA was larger and statistically significant (p < 0.05). Conclusions This is the first study to document measurable levels of BPA in the urine of a population of Mexican women. This study also provides preliminary evidence, based on a single spot urine sample collected during the third trimester, that pregnant women who delivered less than or equal to 37 weeks of gestation and prematurely (< 37 weeks) had higher urinary concentrations of BPA compared to women delivering after 37 weeks.