Human flicker electroretinography using different temporal modulations at mesopic and photopic luminance levels

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• 作者：Balázs Vince Nagy ; Mirella Telles Salgueiro Barboni…
• 关键词：Electroretinography ; Mesopic vision ; Photopic vision ; Luminance
• 刊名：Documenta Ophthalmologica
• 出版年：2014
• 出版时间：October 2014
• 年：2014
• 卷：129
• 期：2
• 页码：129-138
• 全文大小：800 KB
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• 作者单位：Balázs Vince Nagy (1) (2) (3)
  Mirella Telles Salgueiro Barboni (1) (2)
  Cristiane Maria Gomes Martins (1) (2)
  Marcelo Fernandes da Costa (1) (2)
  Jan Kremers (4)
  Dora Fix Ventura (1) (2)
  
  1. Neuroscience and Behavior, University of S?o Paulo, S?o Paulo, SP, Brazil
  2. Department of Experimental Psychology, Institute of Psychology, University of S?o Paulo, Av. Prof. Mello Moraes, 1721, 05508-030, S?o Paulo, SP, Brazil
  3. Department of Mechatronics, Optics and Engineering Informatics, Budapest University of Technology and Economics, Budapest, Hungary
  4. Department of Ophthalmology, University Hospital Erlangen, Erlangen, Germany
  
• ISSN：1573-2622

文摘

Background Electroretinographic measurement instruments allow the variation of several stimulation parameters enabling to study a wide range of retinal processes. The purpose of the present study was to measure human flicker electroretinograms (ERGs) varying temporal modulation, temporal frequency and mean luminance in the photopic and higher mesopic ranges where the change from cone to rod dominance occurs. Methods Fourteen healthy subjects (mean age?=?31?±?6) participated in this study. ERG recordings were performed with the RetiPort system (Roland Consult, Germany). The stimuli were ON and OFF sawtooth waves, square wave and sine wave. The temporal frequencies were 4 and 8?Hz. The mean luminance varied from 1 to 60?cd/m2. Results The results confirmed the possibility to distinguish between rod- and cone-dominated retinal responses when using the flicker ERG at different temporal frequencies and luminances. We have also evaluated the responses at luminance levels at which the transition between rod- and cone-dominated responses occurs. This transition between rod- and cone-dominated flicker ERG responses is indicated by a significant change in the response characteristics between 4 and 8?cd/m2 (between 200 and 400 phot Td). Conclusions The findings on the transition between rod- and cone-dominated ERGs along with the demonstration of ERG responses to different temporal flicker modulations might be informative for the electrophysiologists when setting up the stimulus at mesopic and photopic luminance levels.