Targeted analysis of omega-6-derived oxylipins and parent polyunsaturated fatty acids in serum of hepatitis B virus-related hepatocellular carcinoma patients
详细信息 查看全文
- 作者：Yonghai Lu ; Jinling Fang ; Choon Nam Ong ; Shengsen Chen ; Ning Li ; Liang Cui…
- 关键词：Omega ; 6 ; derived oxylipins ; Hepatitis B virus ; Hepatocellular carcinoma ; LC ; MS/MS
- 刊名：Metabolomics
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：13
- 期：1
- 全文大小：
- 刊物主题：Biochemistry, general; Molecular Medicine; Cell Biology; Developmental Biology; Biomedicine, general;
- 出版者：Springer US
- ISSN：1573-3890
- 卷排序：13
文摘
IntroductionArachidonic acid (AA)-derived prostaglandins recently have been implicated in pathogenesis of hepatocellular carcinoma (HCC). However, current understanding of omega-6-derived oxylipins that promote this disease remains limited, particularly on oxylipins derived from linoleic acid (LA).