Ultravioletttherapie des chronischen Handekzems

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• 作者：PD Dr. H. Stege (1) (2)
  
• 关键词：UV ; Therapie ; Creme ; PUVA ; Therapie ; PUVA ; Bad ; Therapie ; 311 ; nm ; UV ; B ; Therapie ; 8 ; Methoxypsoralen ; UV therapy ; Cream PUVA therapy ; Bath PUVA therapy ; Narrow ; band UVB therapy ; 8 ; methoxypsoralen
• 刊名：Der Hautarzt
• 出版年：2008
• 出版时间：September 2008
• 年：2008
• 卷：59
• 期：9
• 页码：696-702
• 全文大小：413KB
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• 作者单位：PD Dr. H. Stege (1) (2)
  
  1. Hautklinik, Klinikum Lippe-Lemgo, Rintelner Stra脽e 85, 32657, Lemgo, Deutschland
  2. Hautklinik, Universit盲tsklinikum D眉sseldorf, D眉sseldorf, Deutschland
  
• ISSN：1432-1173

文摘

Treatment of hand eczema is dominated by the administration of topical glucocorticosteriods. If topical treatment fails, the best second-line option is ultraviolet (UV) therapy alone or as combination therapy. UVB and PUVA (psoralen plus UVA) therapy is effective and has relatively few side effects. Due to the localized nature of the disease, topical PUVA therapy is preferable to systemic PUVA treatment. Among the topical methods, cream PUVA therapy is simple, safe and highly effective. Recent clinical studies have demonstrated the therapeutic efficacy of a new retinoid called alitretinoin, a 9-cis-retinoic acid. However, even this form of treatment does not lead to a complete cure in all patients. Under the primacy of multimodal treatment, UV therapy should be administered as combination therapy if oral retinoids are not sufficiently effective.