Comparison of Clinical Laboratory Standards Institute and European Committee on Antimicrobial Susceptibility Testing guidelines for the interpretation of antibiotic susceptibility at a University teaching hospital in Nairobi, Kenya: a cross-sectional stu
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- 作者：Ali Kassim ; Geoffrey Omuse ; Zul Premji…
- 关键词：European Committee on Antimicrobial Susceptibility Testing (EUCAST) ; Clinical Laboratory Standards Institute (CLSI) ; Antimicrobial susceptibility testing (AST) ; Minimum inhibitory concentrations (MIC)
- 刊名：Annals of Clinical Microbiology and Antimicrobials
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：15
- 期：1
- 全文大小：996 KB
- 刊物主题：Medical Microbiology; Infectious Diseases;
- 出版者：BioMed Central
- ISSN：1476-0711
文摘
Background The Clinical Laboratory Standards Institute (CLSI) and the European Committee on Antimicrobial Susceptibility Testing (EUCAST) guidelines are the most popular breakpoint guidelines used in antimicrobial susceptibility testing worldwide. The EUCAST guidelines are freely available to users while CLSI is available for non-members as a package of three documents for US $500 annually. This is prohibitive for clinical microbiology laboratories in resource poor settings. We set out to compare antibiotic susceptibility determined by the two guidelines to determine whether adoption of EUCAST guidelines would significantly affect our susceptibility patterns.