The effect of vitamin C on the ratio of collagen types I and III in the periprosthesis area in mice
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- 作者：S. V. Ivanov ; I. S. Ivanov ; A. V. Tsukanov ; G. N. Gafarov…
- 关键词：vitamin C ; polarized light microscopy ; Parietene ; collagen ; endoprosthesis ; ventral hernia
- 刊名：Cell and Tissue Biology
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：10
- 期：6
- 页码：453-457
- 全文大小：
- 刊物主题：Cell Biology;
- 出版者：Pleiades Publishing
- ISSN：1990-5203
- 卷排序：10
文摘
The aim of this study was to examine the collagen-stimulating effect of ascorbic acid on the growth of the Parieten ProGrip implanted synthetic hernia prosthesis. The characteristics of collagenogenesis in the anterior abdominal wall were assayed with polarized microscopy. We suggest a new way to stimulate a reparation process with ascorbic acid that will help to optimize forming functionally matured structures of connective tissue of the anterior abdominal wall surrounding endoprosthesis. The results of our investigation show that vitamin C has a positive effect on the collagen synthesis in the periprosthetic capsule for any type of endoprosthesis. This was proven by the statistically significant increase in the ratio of collagen I and III types with vitamin C to the animal diet.