Gelsolin (GSN) induces cardiomyocyte hypertrophy and BNP expression via p38 signaling and GATA-4 transcriptional factor activation
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  • 作者:Wei-Syun Hu (1) (2)
    Tsung-Jung Ho (3) (4)
    Peiying Pai (5)
    Li-Chin Chung (6)
    Chia-Hua Kuo (7)
    Sheng-Huang Chang (8)
    Fuu-Jen Tsai (3)
    Chang-Hai Tsai (9)
    Yu-Chi Jie (10)
    Ying-Ming Liou (11)
    Chih-Yang Huang (10) (12) (3)
  • 关键词:Cardiac hypertrophy ; Gelsolin (GSN) ; Cytoskeleton
  • 刊名:Molecular and Cellular Biochemistry
  • 出版年:2014
  • 出版时间:May 2014
  • 年:2014
  • 卷:390
  • 期:1-2
  • 页码:263-270
  • 全文大小:2,650 KB
  • 参考文献:1. Cartwright EJ, Oceandy D, Austin C, Neyses L (2011) Ca2+ signalling in cardiovascular disease: the role of the plasma membrane calcium pumps. Sci China Life Sci 54(8):691鈥?98 CrossRef
    2. Heineke J, Molkentin JD (2006) Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat Rev Mol Cell Biol 7(8):589鈥?00 CrossRef
    3. Lorell BH, Carabello BA (2000) Left ventricular hypertrophy: pathogenesis, detection, and prognosis. Circulation 102(4):470鈥?79 CrossRef
    4. Yamamoto S, Kita S, Iyoda T, Yamada T, Iwamoto T (2011) New molecular mechanisms for cardiovascular disease: cardiac hypertrophy and cell-volume regulation. J Pharmacol Sci 116(4):343鈥?49 CrossRef
    5. Tezuka F, Takahashi T (1976) Pathology of cardiac hypertrophy in pressure overload. Jpn Circ J 40(10):1111鈥?118 CrossRef
    6. Johnson GL, Lapadat R (2002) Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 298(5600):1911鈥?912 CrossRef
    7. Sugden PH, Clerk A (1998) 鈥淪tress-responsive鈥?mitogen-activated protein kinases (c-Jun N-terminal kinases and p38 mitogen-activated protein kinases) in the myocardium. Circ Res 83(4):345鈥?52 CrossRef
    8. Liang F, Lu S, Gardner DG (2000) Endothelin-dependent and -independent components of strain-activated brain natriuretic peptide gene transcription require extracellular signal regulated kinase and p38 mitogen-activated protein kinase. Hypertension 35(1 Pt 2):188鈥?92 CrossRef
    9. Garrington TP, Johnson GL (1999) Organization and regulation of mitogen-activated protein kinase signaling pathways. Curr Opin Cell Biol 11(2):211鈥?18 CrossRef
    10. Tenhunen O, Sarman B, Kerkela R, Szokodi I, Papp L, Toth M, Ruskoaho H (2004) Mitogen-activated protein kinases p38 and ERK 1/2 mediate the wall stress-induced activation of GATA-4 binding in adult heart. J Biol Chem 279(23):24852鈥?4860 CrossRef
    11. Kerkela R, Pikkarainen S, Majalahti-Palviainen T, Tokola H, Ruskoaho H (2002) Distinct roles of mitogen-activated protein kinase pathways in GATA-4 transcription factor-mediated regulation of B-type natriuretic peptide gene. J Biol Chem 277(16):13752鈥?3760 CrossRef
    12. Silacci P, Mazzolai L, Gauci C, Stergiopulos N, Yin HL, Hayoz D (2004) Gelsolin superfamily proteins: key regulators of cellular functions. Cell Mol Life Sci 61(19鈥?0):2614鈥?623 CrossRef
    13. Sun HQ, Yamamoto M, Mejillano M, Yin HL (1999) Gelsolin, a multifunctional actin regulatory protein. J Biol Chem 274(47):33179鈥?3182 CrossRef
    14. Li GH, Shi Y, Chen Y, Sun M, Sader S, Maekawa Y, Arab S, Dawood F, Chen M, De Couto G et al (2009) Gelsolin regulates cardiac remodeling after myocardial infarction through DNase I-mediated apoptosis. Circ Res 104(7):896鈥?04 CrossRef
    15. Yin HL, Stossel TP (1979) Control of cytoplasmic actin gel鈥搒ol transformation by gelsolin, a calcium-dependent regulatory protein. Nature 281(5732):583鈥?86 CrossRef
    16. McGough AM, Staiger CJ, Min JK, Simonetti KD (2003) The gelsolin family of actin regulatory proteins: modular structures, versatile functions. FEBS Lett 552(2鈥?):75鈥?1 CrossRef
    17. Kwiatkowski DJ (1999) Functions of gelsolin: motility, signaling, apoptosis, cancer. Curr Opin Cell Biol 11(1):103鈥?08 CrossRef
    18. Li GH, Arora PD, Chen Y, McCulloch CA, Liu P (2012) Multifunctional roles of gelsolin in health and diseases. Med Res Rev 32(5):999鈥?025 CrossRef
    19. Yang J, Moravec CS, Sussman MA, DiPaola NR, Fu D, Hawthorn L, Mitchell CA, Young JB, Francis GS, McCarthy PM et al (2000) Decreased SLIM1 expression and increased gelsolin expression in failing human hearts measured by high-density oligonucleotide arrays. Circulation 102(25):3046鈥?052 CrossRef
    20. Mani SK, Shiraishi H, Balasubramanian S, Yamane K, Chellaiah M, Cooper G, Banik N, Zile, Kuppuswamy D (2008) In vivo administration of calpeptin attenuates calpain activation and cardiomyocyte loss in pressure-overloaded feline myocardium. Am J Physiol Heart Circ Physiol 295(1):H314鈥揌326 CrossRef
    21. Suhler E, Lin W, Yin HL, Lee WM (1997) Decreased plasma gelsolin concentrations in acute liver failure, myocardial infarction, septic shock, and myonecrosis. Crit Care Med 25(4):594鈥?98 CrossRef
    22. Towbin JA, Bowles NE (2002) The failing heart. Nature 415(6868):227鈥?33 CrossRef
    23. Hunter JJ, Chien KR (1999) Signaling pathways for cardiac hypertrophy and failure. N Engl J Med 341(17):1276鈥?283 CrossRef
    24. Nishio R, Matsumori A (2009) Gelsolin and cardiac myocyte apoptosis: a new target in the treatment of postinfarction remodeling. Circ Res 104(7):829鈥?31 CrossRef
    25. Molkentin JD, Lu JR, Antos CL, Markham B, Richardson J, Robbins J, Grant SR, Olson EN (1998) A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell 93(2):215鈥?28 CrossRef
    26. Huang CY, Lee SD (2012) Possible pathophysiology of heart failure in obesity: cardiac apoptosis. BioMedicine 2(1):36鈥?0
    27. Roux PP, Blenis J (2004) ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions. Microbiol Mol Biol Rev 68(2):320鈥?44
    28. Wright CD, Chen Q, Baye NL, Huang Y, Healy CL, Kasinathan S, O鈥機onnell TD (2008) Nuclear alpha1-adrenergic receptors signal activated ERK localization to caveolae in adult cardiac myocytes. Circ Res 103(9):992鈥?000
  • 作者单位:Wei-Syun Hu (1) (2)
    Tsung-Jung Ho (3) (4)
    Peiying Pai (5)
    Li-Chin Chung (6)
    Chia-Hua Kuo (7)
    Sheng-Huang Chang (8)
    Fuu-Jen Tsai (3)
    Chang-Hai Tsai (9)
    Yu-Chi Jie (10)
    Ying-Ming Liou (11)
    Chih-Yang Huang (10) (12) (3)

    1. PhD Program for Aging, China Medical University, Taichung, Taiwan, ROC
    2. Division of Cardiology, Department of Internal Medicine, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan, ROC
    3. School of Chinese Medicine, China Medical University, Taichung, Taiwan, ROC
    4. Chinese Medicine Department, China Medical University, Beigang Hospital, Beigang, Taiwan, ROC
    5. Division of Cardiology, China Medical University Hospital, Taichung, Taiwan, ROC
    6. Department of Hospital and Health Care Administration, Chia Nan University of Pharmacy & Science, Tainan County, Taiwan, ROC
    7. Laboratory of Exercise Biochemistry, Taipei Physical Education College, Taipei, Taiwan, ROC
    8. Department of Health, Tsao-Tun Psychiatric Center, Executive Yuan, Taiwan, ROC
    9. Department of Healthcare Administration, Asia University, Taichung, Taiwan, ROC
    10. Graduate Institute of Basic Medical Science, China Medical University, Taichung, Taiwan, ROC
    11. Department of Life Sciences, National Chung-Hsing University, Taichung, Taiwan, ROC
    12. Department of Health and Nutrition Biotechnology, Asia University, Taichung, Taiwan, ROC
  • ISSN:1573-4919
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