Haemodynamic and functional consequences of the iatrogenic atrial septal defect following Mitraclip therapy
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- 作者：E. A. Hart ; K. Zwart ; A. J. Teske ; M. Voskuil ; P. R. Stella…
- 关键词：MitraClip ; Iatrogenic atrial septal defect ; Mitral regurgitation
- 刊名：Netherlands Heart Journal
- 出版年：2017
- 出版时间：February 2017
- 年：2017
- 卷：25
- 期：2
- 页码：137-142
- 全文大小：382KB
- 刊物主题：Cardiology; Medical Education;
- 出版者：Bohn Stafleu van Loghum
- ISSN：1876-6250
- 卷排序：25
文摘
Percutaneous MitraClip placement for treatment of severe mitral regurgitation in high surgical risk patients is a commonly performed procedure and requires a transseptal puncture to reach the left atrium. The resulting iatrogenic atrial septal defect (iASD) is not routinely closed, yet the haemodynamic and functional consequences of a persisting defect are not fully understood. Despite positive effects such as acute left atrial pressure relief, persisting iASDs are associated with negative consequences, namely significant bidirectional shunting and subsequent worse clinical outcome. Percutaneous closure of the iASD may therefore be desirable in selected cases. In this review we discuss the available literature on this matter.