Uniform design ray in the assessment of combined toxicities of multi-component mixtures

详细信息    查看全文

• 作者：Shu-Shen Liu ; Qian-Fen Xiao ; Jin Zhang ; Mo Yu
• 关键词：Chemical mixture ; Uniform design ; Ray design ; Mixture ratio ; Concentration–response relationship ; Toxicity interaction
• 刊名：Chinese Science Bulletin
• 出版年：2016
• 出版时间：January 2016
• 年：2016
• 卷：61
• 期：1
• 页码：52-58
• 全文大小：677 KB
• 参考文献：1.Zhuang W, Chen JW, Huang LP et al (2009) Integrated fuzzy concentration addition-independent action (IFCA-IA) model outperforms two-stage prediction (TSP) for predicting mixture toxicity. Chemosphere 74:735–740CrossRef
  2.Nuerla ALJ, Qiao XL, Li J et al (2013) Effects of substituent position on the interactions between PBDEs/PCBs and DOM. Chin Sci Bull 58:884–889CrossRef
  3.Dou RN, Liu SS, Mo LY et al (2011) A novel direct equipartition ray design (EquRay) procedure for toxicity interaction between ionic liquid and dichlorvos. Environ Sci Pollut Res 18:734–742CrossRef
  4.Silva ARR, Cardoso DN, Cruz A et al (2015) Ecotoxicity and genotoxicity of a binary combination of triclosan and carbendazim to Daphnia magna. Ecotoxicol Environ Saf 115:279–290CrossRef
  5.Palkar RR, Shilapuram V (2015) Development of a model for the prediction of hydrodynamics of a liquid-solid circulating fluidized beds: a full factorial design approach. Powder Technol 280:103–112CrossRef
  6.Shahabadi SMS, Reyhani A (2014) Optimization of operating conditions in ultrafiltration process for produced water treatment via the full factorial design methodology. Sep Purif Technol 132:50–61CrossRef
  7.Fang KT, Lin DKJ, Winker P et al (2000) Uniform design: theory and application. Technometrics 42:237–248CrossRef
  8.Parvez S, Venkataraman C, Mukherji S (2008) Toxicity assessment of organic contaminants: evaluation of mixture effects in model industrial mixtures using 2 n full factorial design. Chemosphere 73:1049–1055CrossRef
  9.Moser VC, MacPhail RC, Gennings C (2003) Neurobehavioral evaluations of mixtures of trichloroethylene, heptachlor, and di(2-ethylhexyl)phthlate in a full-factorial design. Toxicology 188:125–137CrossRef
  10.Wu YG, Lin CX, Yuan L (2008) Phototaxis index of Daphnia carinata as an indicator of joint toxicity of copper, cadmium, zinc, nitrogen and phosphorus in aqueous solutions. Ecol Indic 8:69–74CrossRef
  11.Hu JY, Li J, Wang JS et al (2014) Synergistic effects of perfluoroalkyl acids mixtures with J-shaped concentration-responses on viability of a human liver cell line. Chemosphere 96:81–88CrossRef
  12.Chen C, Wang Y, Qian Y et al (2015) The synergistic toxicity of the multiple chemical mixtures: implications for risk assessment in the terrestrial environment. Environ Int 77:95–105CrossRef
  13.Norgaard KB, Cedergreen N (2010) Pesticide cocktails can interact synergistically on aquatic crustaceans. Environ Sci Pollut Res 17:957–967CrossRef
  14.Moser VC, Simmons JE, Gennings C (2006) Neurotoxicological interactions of a five-pesticide mixture in preweanling rats. Toxicol Sci 92:235–245CrossRef
  15.Jonker MJ, Svendsen C, Bedaux JJM et al (2005) Significance testing of synergistic/antagonistic, dose level-dependent, or dose ratio-dependent effects in mixture dose–response analysis. Environ Toxicol Chem 24:2701–2713CrossRef
  16.Fang KT (1980) The uniform design: application of number-theoretic methods in experimental design. Acta Math Appl Sin 3:363–372 (in Chinese)
  17.Wang Y, Fang KT (1981) A note on uniform distribution and experimental design. Chin Sci Bull 26:485–489
  18.Fang KT, Jk Li (1995) Some new results on the uniform design. Chin Sci Bull 40:268–272
  19.Liu SS, Song XQ, Liu HL et al (2009) Combined photobacterium toxicity of herbicide mixtures containing one insecticide. Chemosphere 75:381–388CrossRef
  20.Zhang YH, Liu SS, Song XQ et al (2008) Prediction for the mixture toxicity of six organophosphorus pesticides to the luminescent bacterium Q67. Ecotox Environ Safe 71:880–888CrossRef
  21.Liu SS, Zhang J, Zhang YH et al (2012) APTox: assessment and prediction on toxicity of chemical mixtures. Acta Chim Sin 70:1511–1517 (in Chinese)CrossRef
  22.Liu SS, Wang CL, Zhang J et al (2013) Combined toxicity of pesticide mixtures on green algae and photobacteria. Ecotox Environ Safe 95:98–103CrossRef
  23.Zhang J, Liu SS, Zhu XW (2014) Benefits from hazards: mixture hormesis induced by emim Cl despite its individual inhibitions. Chemosphere 112:420–426CrossRef
  24.Wang MC, Liu SS, Chen F (2014) Predicting the time-dependent toxicities of three triazine herbicide mixtures to V. qinghaiensis sp Q67 using the extended concentration addition model. Acta Chim Sin 72:56–60 (in Chinese)CrossRef
  25.Zhang J, Liu SS, Xiao QF et al (2014) Identifying the component responsible for antagonism within ionic liquid mixtures using the up-to-down procedure integrated with a uniform design ray method. Ecotox Environ Safe 107:16–21CrossRef
  26.Zhang J, Liu SS, Liu HL et al (2011) A novel method dependent only on the mixture information (MIM) for evaluating the toxicity of mixture. Environ Pollut 159:1941–1947CrossRef
  27.Scholze M, Boedeker W, Faust M et al (2001) A general best-fit method for concentration-response curves and the estimation of low-effect concentrations. Environ Toxicol Chem 20:448–457CrossRef
  28.Zhu XW, Liu SS, Ge HL et al (2009) Comparison between two confidence intervals of dose–response relationships. China Environ Sci 29:113–117 (in Chinese)
  29.Zhu XW, Liu SS, Qin LT et al (2013) Modeling non-monotonic dose–response relationships: model evaluation and hormetic quantities exploration. Ecotox Environ Safe 89:130–136CrossRef
  30.Wang N, Wang XC, Ma X (2015) Characteristics of concentration-inhibition curves of individual chemicals and applicability of the concentration addition model for mixture toxicity prediction. Ecotox Environ Safe 113:176–182CrossRef
  31.Chen F, Liu SS, Duan XT et al (2014) Predicting the mixture effects of three pesticides by integrating molecular simulation with concentration addition modeling. RSC Adv 4:32256–32262CrossRef
  32.Liu SS, Liu L, Chen F (2013) Application of the concentration addition model in the assessment of chemical mixture toxicity. Acta Chim Sin 71:1335–1340 (in Chinese)CrossRef
  33.Ge HL, Liu SS, Zhu XW et al (2011) Predicting hormetic effects of ionic liquid mixtures on luciferase activity using the concentration addition model. Environ Sci Technol 45:1623–1629CrossRef
  34.Backhaus T, Arrhenius A, Blanck H (2004) Toxicity of a mixture of dissimilarly acting substances to natural algal communities: predictive power and limitations of independent action and concentration addition. Environ Sci Technol 38:6363–6370CrossRef
  35.Faust M, Altenburger R, Backhaus T et al (2003) Joint algal toxicity of 16 dissimilarly acting chemicals is predictable by the concept of independent action. Aquat Toxicol 63:43–63CrossRef
  36.Zhang J, Liu SS, Yu ZY et al (2012) Significant contributions of ionic liquids containing tetrafluoroborate and trifluoromethanesulfonate to antagonisms and synergisms in multi-component mixtures. J Hazard Mater 209:158–163CrossRef
  37.Zhang J, Liu SS, Yu ZY et al (2013) The time-dependent hormetic effects of 1-alkyl-3-methylimidazolium chloride and their mixtures on Vibrio qinghaiensis sp. -Q67. J Hazard Mater 258:70–76CrossRef
  38.Zhang YH, Liu SS, Liu HL et al (2010) Evaluation of the combined toxicity of 15 pesticides by uniform design. Pest Manag Sci 66:879–887
  
• 作者单位：Shu-Shen Liu (1)
  Qian-Fen Xiao (1)
  Jin Zhang (2)
  Mo Yu (1)
  
  1. Key Laboratory of Yangtze River Water Environment, Ministry of Education, College of Environmental Science and Engineering, Tongji University, Shanghai, 200092, China
  2. College of Environment and Energy Engineering, Anhui Jianzhu University, Hefei, 230601, China
  
• 刊物主题：Science, general; Life Sciences, general; Physics, general; Chemistry/Food Science, general; Earth Sciences, general; Engineering, general;
• 出版者：Springer Berlin Heidelberg
• ISSN：1861-9541

文摘

Multi-component mixture (MCM) is a complicated chemical system that contains a great deal of mixture rays with various mixture ratios, and each ray includes many mixtures with different concentration levels . Currently, in combined toxicity field, almost all studies on MCM focus on the mixtures designed by the equivalent-effect concentration ratio (EECR) procedure. However, the EECR mixtures cannot represent the whole mixture system because the EECR mixtures are located on one mixture ray in concentration space formed by multiple components. In our view, some optimal experimental design such as the uniform design (UD) should be used to effectively select many representative mixture rays from the MCM system, instead of single EECR ray. The uniform design ray (UD-ray) integrating UD idea with fixed-ratio ray design can systematically and comprehensively measure the combined toxicity changes in the MCM system. This review introduces the operation method, construction of uniform table and corresponding usable table, and some cases of application of the UD-ray to help readers easily use UD-ray in their MCM toxicity assessment.