Changes in Swallowing Physiology and Patient Perception of Swallowing Function Following Chemoradiation for Head and Neck Cancer
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- 作者：Nicole M. Rogus-Pulia (1) (2)
Margaret C. Pierce (3)
Bharat B. Mittal (4)
Steven G. Zecker (5)
Jeri A. Logemann (5) - 关键词：Deglutition ; Deglutition disorders ; Dysphagia ; Chemoradiation ; Head and neck cancer ; Perception ; Swallow efficiency
- 刊名：Dysphagia
- 出版年：2014
- 出版时间：April 2014
- 年：2014
- 卷：29
- 期：2
- 页码：223-233
- 全文大小：507 KB
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Margaret C. Pierce (3)
Bharat B. Mittal (4)
Steven G. Zecker (5)
Jeri A. Logemann (5)
1. William S. Middleton Memorial Veterans Hospital, 2500 Overlook Terrace, Madison GRECC (11G), Room D5216, Madison, WI, 53705, USA
2. Department of Medicine, School of Medicine and Public Health, Speech, Swallowing, and Dining Enhancement Program, University of Wisconsin-Madison, Madison, WI, USA
3. Radiation Oncology, Northwestern Memorial Hospital, Chicago, IL, USA
4. Department of Radiation Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
5. Department of Communication Sciences and Disorders, Northwestern University, Frances Searle Building, Evanston, IL, 60208, USA - ISSN：1432-0460
文摘
Patients treated with chemoradiation for head and neck cancer often report difficulty with swallowing and are frequently diagnosed with dysphagia. The extent to which patient awareness of dysphagia corresponds to observed physiologic changes in swallowing is unclear. The purpose of this study was to determine how both patient awareness of swallowing function and swallowing physiology individually change following chemoradiation and then to clarify the relationship between them. Twenty-one patients with head and neck cancer treated with chemoradiation were assessed before and after treatment and matched with twenty-one control subjects. The modified barium swallow test was utilized to examine swallowing physiology. Each subject was also given a series of items regarding awareness of specific dysphagia symptoms. Results showed decreased swallow efficiencies, higher percentages of residue, and more occurrences of penetration and aspiration following chemoradiation. Patients also had significantly higher ratings for 4 of the 12 items (“dry mouth,-“food sticking in my mouth,-“need water to help food go down,-and “change in sense of taste-. Only one strong and significant correlation was found between ratings for “I have difficulty swallowing-and swallow efficiency values. Based on these findings, it appears that patients sense a general difficulty with swallowing but have less awareness of specific symptoms of dysphagia.