Fabrication and Applications of Micro/Nanostructured Devices for Tissue Engineering
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- 作者：Tania Limongi ; Luca Tirinato ; Francesca Pagliari ; Andrea Giugni…
- 关键词：Nanomaterials ; Nanostructures ; Microfabrication ; Nanofabrication ; Device ; Tissue engineering
- 刊名：Nano-Micro Letters
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：9
- 期：1
- 全文大小：2,119 KB
- 刊物类别：Nanotechnology and Microengineering; Nanotechnology; Nanoscale Science and Technology;
- 刊物主题：Nanotechnology and Microengineering; Nanotechnology; Nanoscale Science and Technology;
- 出版者：Springer Berlin Heidelberg
- ISSN：2150-5551
- 卷排序：9
文摘
Nanotechnology allows the realization of new materials and devices with basic structural unit in the range of 1–100 nm and characterized by gaining control at the atomic, molecular, and supramolecular level. Reducing the dimensions of a material into the nanoscale range usually results in the change of its physiochemical properties such as reactivity, crystallinity, and solubility. This review treats the convergence of last research news at the interface of nanostructured biomaterials and tissue engineering for emerging biomedical technologies such as scaffolding and tissue regeneration. The present review is organized into three main sections. The introduction concerns an overview of the increasing utility of nanostructured materials in the field of tissue engineering. It elucidates how nanotechnology, by working in the submicron length scale, assures the realization of a biocompatible interface that is able to reproduce the physiological cell–matrix interaction. The second, more technical section, concerns the design and fabrication of biocompatible surface characterized by micro- and submicroscale features, using microfabrication, nanolithography, and miscellaneous nanolithographic techniques. In the last part, we review the ongoing tissue engineering application of nanostructured materials and scaffolds in different fields such as neurology, cardiology, orthopedics, and skin tissue regeneration.