A practical experience of dose modeling for proton pencil beam scanning in KNCC

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• 作者：Kwanghyun Jo ; Mi Young Kim ; Jong Hwi Jeong…
• 关键词：Proton ; Pencil beam scanning ; Dose modelling
• 刊名：Journal of the Korean Physical Society
• 出版年：2015
• 出版时间：July 2015
• 年：2015
• 卷：67
• 期：1
• 页码：108-115
• 全文大小：948 KB
• 参考文献：[1]M. Lodge, M. Pijls-Johannesma, L. Stirk, A. J. Munro, D. De Ruysscher and T. Jefferson, Radiotherapy and Oncology 83, 110 (2007).View Article
  [2]E. Pedroni et al, Medi. Phys. 22, 37 (1995).View Article
  [3]D. C. Weber, H. P. Rutz, E. S. Pedroni, A. Bolsi, B. Timmermann, J. Verwey, A. Lomax and G. Goitein, Int. J. Radiat. Oncol. Biol. Phys. 63, 401 (2005); B. Rombi et al., Int. J. Radiat. Oncol. Biol. Phys. 86, 578 (2013); A. Staab et al., Int. J. Radiat. Oncol. Biol. Phys. 81, e489 (2011).View Article
  [4]B. Schaffner, Phys. Med. Biol. 53, 1545 (2008).View Article
  [5]L. Lin, C. G. Ainsley, T. Mertens, O. De Wilde, P. T. Talla and J. E. McDonough, Phys. Med. Biol. 58, N171 (2013).View Article
  [6]International Commission on Radiation Units and Measurements. (1993); W. Ulmer, Radiat. Phys. Chem. 6, 1089 (2007).
  [7]G. O. Sawakuchi et al., Phys. Med. Biol. 55, 3467 (2010); P. N. Mobit, G. A. Sandison and C. Bloch, Medi. Phys. 27, 2780 (2000); X. Zhang et al., Phys. Medi. Biol. 56, 7725 (2011).View Article
  [8]B. Clasie, N. Depauw, M. Fransen, C. Gom, H. R. Panahandeh, J. Seco, J. Flanz and H. M. Kooy, Phys. Medi. Biol. 57, 1147. (2012).
  [9]G. Molire, Z. Naturforsch 3a, 78 (1948); V. L. Highland, NIM 129, 497 (1975); G. R. Lynch and O. I. Dahl, NIM B58, 6 (1991).
  [10]Y. Li, R. X. Zhu, N. Sahoo, A. Anand and X. Zhang, Phys. Medi. Biol. 57, 983 (2012).View Article
  [11]X. R. Zhu et al., Medi. phys. 40, 041723 (2013); M. T. Gillin et al., Medi. phys. 37, 154 (2010).View Article
  [12]L. Lin, C. G. Ainsley and J. E. McDonough, Phys. Medi. Biol. 58, 6193 (2013); L. Lin, C. G. Ainsley, T. D. Solberg and J. E. Mc-Donough, Phys. Medi. Biol. 59, 493. (2014); G. O. Sawakuchi et al., Phys. Medi. Biol. 55, 3467 (2010).View Article
  [13]J. Schwaab, S. Brons, J. Fieres and K. Parodi, Phys. Medi. Biol. 56, 7813 (2011); G. Ciangaru, N. Sahoo, X. R. Zhu, G. O. Sawakuchi and M. T. Gillin, Phys. Medi. Biol. 54, 7285 (2009); E. Pedroni, S. Scheib, A. Coray, M. Grossmann, S. Lin and A. Lomax, Phys. Medi. Biol. 50, 541 (2005).View Article
  [14]G. O. Sawakuchi, U. Titt, D. Mirkovic, G. Ciangaru, X. R. Zhu, N. Sahoo, M. Gillin and R. Mohan, Phys. Medi. Biol. 55, 711. (2010).View Article
  
• 作者单位：Kwanghyun Jo (1)
  Mi Young Kim (1)
  Jong Hwi Jeong (1)
  EunHee Jeang (1)
  Haksoo Kim (1)
  Seyjoon Park (1)
  Jeong-Hoon Park (1)
  Young Kyung Lim (1)
  Dongho Shin (1)
  Se Byeong Lee (1)
  Kwanghyun Jo (2)
  Chiyoung Jeong (3)
  
  1. Proton Therapy Center, National Cancer Center, Goyang, 410-769, Korea
  2. Department of Radiation Oncology, Samsung Medical Center, Seoul, 135-710, Korea
  3. Department of Radiation Oncology, Asan Medical Center, Seoul, 138-736, Korea
  
• 刊物主题：Physics, general; Theoretical, Mathematical and Computational Physics; Particle and Nuclear Physics;
• 出版者：Springer Netherlands
• ISSN：1976-8524

文摘

Dose modeling of proton pencil beam scanning (PBS) in Eclipse V10 (Varian Medical Systems, Palo Alto) requires absolute integral depth dose (IDD) curves and spot profiles for all energies. IDDs are measured by using a Bragg peak chamber (BPC, PTW; radius: 4.08 cm) and a threedimensional (3D) water phantom (RFA300, IBA, Louvain-la-Neuve, Belgium). The energy range is 99.3 MeV - 226.9 MeV, and the number of measured beam energies is 133, which corresponds to the number of available energy degrader steps. Relative IDDs are converted to absolute IDDs by measuring the outputs at a shallow depth (i.e., 2 cm) with the calibrated NDWkq of the BPC. In the present study, in-air spot profiles were collected by using a homemade device at 8 different positions, 0 cm,-10 cm,-20 cm,-30 cm and 40 cm, from the isocenter with and without a range shifter (RS). Additional high monitor unit (MU) measurements were performed to acquire a high signal-to-noise ratio (SNR) in the low-dose region. Without the RS, the smallest in-air spot size at the isocenter was approximately 4.5 mm for 226.9 MeV, and the largest size was 11 mm for 99.3 MeV. The water-equivalent thickness of the RS is 74.4 mm. At National Cancer Center, Korea, we measured 133 IDDs and 2128 x, y spot profiles from Feb. 2014 to July 2014, which sufficed for dose modeling. This is the first proton pencil beam dose modeling data in Korea. Indeed, our experience should prove useful to other institutions, especially where the IBA proton machine is used with Eclipse.