刊物主题:Biomedicine Cancer Research Pharmacology and Toxicology Oncology
出版者:Springer Berlin / Heidelberg
ISSN:1432-0843
卷排序:78
文摘
PurposeNEO-102 is a novel chimeric IgG1 monoclonal antibody which recognizes a variant form of MUC5AC expressed specifically by human pancreatic and colorectal tumors. Preclinical models have demonstrated encouraging signs of anti-tumor activity through antibody-dependent cell-mediated cytotoxicity.