Polyfunctional imidazoles: IX. Synthesis of 1-aryl-5-(2-aryl-3,4-dihydro-2H-pyrrol-4-yl)-4-chloro-1H-imidazoles

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• 作者：O. Ya. Mel鈥檔ik (1)
  V. A. Chornous (2)
  M. V. Vovk (3)
  
  1. Ivano-Frankovsk National Medical University ; Ivano-Frankovsk ; Ukraine
  2. Bukovina State Medical University ; Chernovtsy ; Ukraine
  3. Institute of Organic Chemistry ; National Academy of Sciences of Ukraine ; ul. Murmanskaya 5 ; Kiev ; 02094 ; Ukraine
  
• 刊名：Russian Journal of Organic Chemistry
• 出版年：2015
• 出版时间：February 2015
• 年：2015
• 卷：51
• 期：2
• 页码：240-244
• 全文大小：235 KB
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• 刊物主题：Organic Chemistry;
• 出版者：Springer US
• ISSN：1608-3393

文摘

1-Aryl-3-(1-aryl-4-chloro-1H-imidazol-5-yl)prop-2-en-1-ones prepared from 1-aryl-4-chloro-1H-imidazole-5-carbaldehydes and methyl aryl ketones reacted with nitromethane affording 1-aryl-3-(1-aryl-4-chloro-1H-imidazol-5-yl)-4-nitrobutan-1-ones which were reduced with zink in acetic acid to obtain 1-aryl-5-(2-aryl-3,4-dihydro-2H-pyrrol-4-yl)-4-chloro-1H-imidazoles.