New lanostane-type triterpene acids from wolfiporia extensa
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- 作者：Gaimei She (1)
Nailiang Zhu (1)
Shuai Wang (1)
Yang Liu (1)
Yinying Ba (1)
Changqing Sun (1)
Renbing Shi (1) - 刊名：Chemistry Central Journal
- 出版年：2012
- 出版时间：December 2012
- 年：2012
- 卷：6
- 期：1
- 全文大小：175KB
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Nailiang Zhu (1)
Shuai Wang (1)
Yang Liu (1)
Yinying Ba (1)
Changqing Sun (1)
Renbing Shi (1)
1. School of Chinese Pharmacy, Beijing University of Chinese Medicine, No. 6, Zhonghuan South Road, Wangjing District, Beijing, 100102, People’s Republic of China - ISSN：1752-153X
文摘
Backgroud Dried sclerotia of Wolfiporia extensa (Polyporaceae) is used to invigorate the spleen and to tranquilize the mind in Chinese herbal medicine. Lanostane-type triterpene acids were regard as major secondary metabolites from dried sclerotia of W. extensa. Results Three new lanostane-type triterpene acids, 3-epi-benzoyloxyl-dehydrotumulosic acid (1), 3-epi-(3-O-methyl malonyloxy)-dehydrotumulosic acid (2) and 3-epi-(3-hydroxy-3-methylglutaryloxyl)-dehydrotumulosic acid (3), were isolated from the sclerotia of W. extensa, together with 3 known lanostane derivatives (4-strong class="a-plus-plus">6). Their structures were elucidated on the basis of spectroscopic analysis, including 1D and 2D-NMR techniques. Conclusion Six lanostane derivatives including three new triterpene acids and three known compounds were reported from the sclerotia of W. extensa in this paper.