Pharmacokinetic parameters of gefitinib predict efficacy and toxicity in patients with advanced non-small cell lung cancer harboring EGFR mutations

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• 作者：Kosuke Mizoguchi ; Yoichi Nakamura ; Kazumi Sano…
• 刊名：Cancer Chemotherapy and Pharmacology
• 出版年：2016
• 出版时间：August 2016
• 年：2016
• 卷：78
• 期：2
• 页码：377-382
• 全文大小：418 KB
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Biomedicine
  Cancer Research
  Pharmacology and Toxicology
  Oncology
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1432-0843
• 卷排序：78

文摘

PurposeThe relationship between plasma concentration and antitumor activity of gefitinib was assessed in patients with advanced non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR) mutations.