Long noncoding RNA lncTCF7, induced by IL-6/STAT3 transactivation, promotes hepatocellular carcinoma aggressiveness through epithelial-mesenchymal transition
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- 作者：Jun Wu ; Jun Zhang ; Bin Shen ; Kai Yin…
- 关键词：Hepatocellular carcinoma ; Interleukin ; 6 ; Long noncoding RNA ; Epithelial ; mesenchymal ; transition
- 刊名：Journal of Experimental & Clinical Cancer Research
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：34
- 期：1
- 全文大小：1,799 KB
- 刊物主题：Oncology; Cancer Research;
- 出版者：BioMed Central
- ISSN：1756-9966
文摘
Background Accumulating evidence suggests the pro-inflammatory cytokine interleukin-6 (IL-6) in tumor microenvironment may promote the development of hepatocellular carcinoma (HCC). However, the underlying mechanism remains largely unknown.