Seasonal variation of diseases in children: a 6-year prospective cohort study in a general hospital
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  • 作者:Tessa V. Schrijver ; Paul L. P. Brand ; Jolita Bekhof
  • 关键词:Seasonality ; Seasonal variation ; Variability ; Functional complaints
  • 刊名:European Journal of Pediatrics
  • 出版年:2016
  • 出版时间:April 2016
  • 年:2016
  • 卷:175
  • 期:4
  • 页码:457-464
  • 全文大小:544 KB
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  • 作者单位:Tessa V. Schrijver (1)
    Paul L. P. Brand (1) (2)
    Jolita Bekhof (1)

    1. Princess Amalia Children’s Center, Isala, Dokter van Heesweg 2, 8025 AB, Zwolle, PO Box 10400, 8000 GK, The Netherlands
    2. UMCG Postgraduate School of Medicine, University Medical Center and University of Groningen, Hanzeplein 1,9713 GZ, Postbus 30.001, 9700 RB, Groningen, The Netherlands
  • 刊物主题:Pediatrics;
  • 出版者:Springer Berlin Heidelberg
  • ISSN:1432-1076
文摘
Seasonal variation in pediatrics has been well described in some infectious diseases, asthma, and diabetes, but data on seasonality for other diseases in children are sparse. To explore the extent of seasonal variation of the entire pediatric field, we analyzed diagnostic codes of all newly referred patients (n = 51,054) to our pediatric department of a large teaching hospital in the Netherlands over a 6-year period (2008–2013). Seasonality was analyzed using simple moving averages, the standard error of the mean (SEM) and the percentage monthly variation. We defined seasonal variation as a visually recognizable periodic pattern in every year in combination with a standard error of the mean > 0.20. Four diseases fulfilled our definition of seasonality: respiratory tract infections (peak in January, +107.0 %), gastroenteritis (peak in February–March, +95.8 % and +112.9 %, respectively), functional complaints (peak in March, +34.0 %, and November, +13.4 %), and asthma (peak in March, +27.8 %, and October, +17.5 %). Together, these four categories comprised 21.2 % of all newly referred patients.

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