Neurogenin 3 is important but not essential for pancreatic islet development in humans
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- 作者：Oscar Rubio-Cabezas ; Ethel Codner ; Sarah E. Flanagan ; José L. Gómez…
- 关键词：Diabetes ; Enteric anendocrinosis ; Islet development ; Neonatal diabetes ; Neurogenin 3
- 刊名：Diabetologia
- 出版年：2014
- 出版时间：November 2014
- 年：2014
- 卷：57
- 期：11
- 页码：2421-2424
- 全文大小：99 KB
- 参考文献：1. Gradwohl G, Dierich A, LeMeur M, Guillemot F (2000) / neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc Natl Acad Sci U S A 97:1607-611 3/pnas.97.4.1607" target="_blank" title="It opens in new window">CrossRef
2. Jenny M, Uhl C, Roche C et al (2002) Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium. EMBO J 21:6338-347 3/emboj/cdf649" target="_blank" title="It opens in new window">CrossRef
3. Rukstalis JM, Habener JF (2009) Neurogenin3: a master regulator of pancreatic islet differentiation and regeneration. Islets 1:177-84 3.9877" target="_blank" title="It opens in new window">CrossRef
4. Lyttle BM, Li J, Krishnamurthy M et al (2008) Transcription factor expression in the developing human fetal endocrine pancreas. Diabetologia 51:1169-180 CrossRef
5. Jennings RE, Berry AA, Kirkwood-Wilson R et al (2013) Development of the human pancreas from foregut to endocrine commitment. Diabetes 62:3514-522 337/db12-1479" target="_blank" title="It opens in new window">CrossRef
6. Wang J, Cortina G, Wu SV et al (2006) Mutant neurogenin-3 in congenital malabsorptive diarrhea. N Engl J Med 355:270-80 CrossRef
7. Jensen JN, Rosenberg LC, Hecksher-S?rensen J, Serup P (2007) Mutant neurogenin-3 in congenital malabsorptive diarrhea. N Engl J Med 356:1781-782 3247" target="_blank" title="It opens in new window">CrossRef
8. Rubio-Cabezas O, Jensen JN, Hodgson MI et al (2011) Permanent neonatal diabetes and enteric anendocrinosis associated with biallelic mutations in NEUROG3. Diabetes 60:1349-353 337/db10-1008" target="_blank" title="It opens in new window">CrossRef
9. Pinney SE, Oliver-Krasinski J, Ernst L et al (2011) Neonatal diabetes and congenital malabsorptive diarrhea attributable to a novel mutation in the human neurogenin-3 gene coding sequence. J Clin Endocrinol Metab 96:1960-965 CrossRef
10. Sayar E, Islek A, Yilmaz A, Akcam M, Flanagan SE, Artan R (2013) Extremely rare cause of congenital diarrhea: enteric anendocrinosis. Pediatr Int 55:661-63 CrossRef
11. Ohsie S, Gerney G, Gui D, Kahana D, Martín MG, Cortina G (2009) A paucity of colonic enteroendocrine and/or enterochromaffin cells characterizes a subset of patients with chronic unexplained diarrhea/malabsorption. Hum Pathol 40:1006-014 CrossRef
12. Flasse LC, Pirson JL, Stern DG et al (2013) Ascl1b and Neurod1, instead of Neurog3, control pancreatic endocrine cell fate in zebrafish. BMC Biol 11:78 CrossRef - 作者单位：Oscar Rubio-Cabezas (1)
Ethel Codner (2)
Sarah E. Flanagan (3)
José L. Gómez (4)
Sian Ellard (3)
Andrew T. Hattersley (3)
1. Department of Pediatric Endocrinology, Hospital Infantil Universitario Ni?o Jesús, Instituto de Investigación Sanitaria La Princesa, Avda. Menéndez Pelayo 65, 28007 Madrid, Spain
2. Institute of Maternal and Child Research, University of Chile, Santiago, Chile
3. Institute for Biomedical and Clinical Science, University of Exeter Medical School, Exeter, UK
4. Department of Pediatrics, Complejo Hospitalario Torrecárdenas, Almería, Spain - ISSN：1432-0428
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