Cytokine and neuropeptide levels are associated with pain relief in patients with chronically painful total knee arthroplasty: a pilot study
详细信息 查看全文
- 作者：Jasvinder A. Singh ; Siamak Noorbaloochi ; Keith L. Knutson
- 关键词：Cytokine ; Substance P ; Pain ; Primary total knee arthroplasty ; TKA
- 刊名：BMC Musculoskeletal Disorders
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：18
- 期：1
- 全文大小：321KB
- 刊物主题：Orthopedics; Rehabilitation; Rheumatology; Sports Medicine; Internal Medicine; Epidemiology;
- 出版者：BioMed Central
- ISSN：1471-2474
- 卷排序：18
文摘
BackgroundThere are few studies with an assessment of the levels of cytokines or neuropeptides as correlates of pain and pain relief in patients with painful joint diseases. Our objective was to assess whether improvements from baseline to 2-months in serum cytokine, chemokine and substance P levels were associated with clinically meaningful pain relief at 2-months post-injection in patients with painful total knee arthroplasty (TKA).